Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 481 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06478030Recruiting
Combined screening for stomach and bowel cancer
This study is testing a combined screening method for finding cancer in the stomach and intestines at an early stage. It is for people in Zhejiang Province who are willing to be screened and followed over time.
Jinhua, ZhejiangAges 40–74 - NCT06479811RecruitingPhase 1
Radioactive drug for advanced neuroendocrine and other cancers
This trial tests a new radioactive drug, [212Pb]VMT-Alpha-NET, that targets a protein on certain cancer cells. It is for people with specific types of advanced cancers that have gotten worse and are not responding to standard treatments.
Bethesda, MarylandAges 18–120 - NCT06488274Recruiting
Study of a new infant formula for digestive issues in babies
This trial is testing a new infant formula to see if it helps with common digestive problems like spitting up, colic, or constipation in babies up to 4 months old. It aims to improve symptoms and comfort for infants who are formula-fed.
NiceAges Up to 4 months - NCT06510348Recruiting
Feeding support for ventilated patients with gut issues
This trial tests a special approach to nutrition for patients on breathing machines who have trouble digesting food. It aims to see if the new method helps meet nutritional needs better.
BucharestAges 18 years+ - NCT06514170Recruiting
Stomach and bowel function after aortic surgery
This study looks at how stomach and bowel function changes after major aortic surgery. It may help doctors understand and prevent digestive problems in patients who need extended time on a ventilator after surgery.
Mexico City, TlalpanAges 18 years+ - NCT06515353Recruiting
Gastrointestinal bleeding and atmospheric pressure study
This study looks at how changes in atmospheric pressure might affect gastrointestinal bleeding. If you have had bleeding from your stomach or intestines and live in central Ankara, this trial could help doctors understand if weather plays a role.
Ankara, YenimahalleAges 18 years+ - NCT06523582Recruiting
Genetic study of neuroendocrine tumors in Mexican patients
This study aims to find genetic causes of neuroendocrine tumors in Mexican patients. By understanding your DNA, researchers hope to improve diagnosis and treatment for people with these rare conditions.
Mexico City, Mexico CityAges 18 years+ - NCT06532877Recruiting
Telephone support for advanced GI cancer and caregivers
This study offers telephone-based support for people with advanced gastrointestinal cancer who are experiencing fatigue, and for their family caregivers. It aims to help both you and your caregiver manage the challenges of cancer care together.
Chicago, IllinoisAges 18 years+ - NCT06543316Recruiting
Treating gastric bypass ulcers with low-thermal argon plasma
This study tests a new way to treat painful sores (marginal ulcers) that can happen after gastric bypass surgery. Doctors use a special tool (argon plasma) during an endoscopy to help the sores heal faster, and you will get standard ulcer medicine too.
Boston, MassachusettsAges 18 years+ - NCT06596694RecruitingPhase 1/Phase 2
Patritumab deruxtecan for advanced gastrointestinal cancers
This trial tests a new drug (patritumab deruxtecan) for people with advanced or spreading cancers of the digestive system (including colorectal, bile duct, liver, and stomach/esophageal cancers). The goal is to see if it can shrink tumors or stop them from growing.
Santa Monica, CaliforniaAges 18 years+ - NCT06621277Recruiting
Improving care for young adults with GI cancer
This study aims to improve care for younger adults (ages 18-50) with gastrointestinal (GI) tumors. Researchers will test ways to better support patients during and after treatment. If you are 18-50 and being treated for a GI tumor at Heidelberg University Hospital, you may be able to join.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06630234RecruitingPhase 1/Phase 2
Testing a new drug for advanced GIST with specific gene changes
This trial tests a new targeted therapy drug, DCC-3009, for people with advanced GIST that has a specific gene mutation (KIT or PDGFRA). It's for those who have already tried other targeted treatments and need a new option.
Scottsdate, ArizonaAges 18 years+ - NCT06680583Recruiting
Predicting recovery in cirrhosis with GI bleeding
This study looks at simple body measurements (like blood pressure and heart rate) to help predict how well people with cirrhosis (liver damage) who are having bleeding in their stomach or intestines will recover. It may help doctors make better treatment decisions.
TainanAges Any age - NCT06687057Recruiting
Heart rate training for anxiety and stomach issues
This study tests whether a special breathing and heart-rate training program (called HRV biofeedback) can help people who have both anxiety and a sensitive stomach or bowel (functional gastrointestinal disorder). If you often feel anxious and have belly discomfort without a clear medical cause, this training might improve both your digestion and your mood.
MilanAges 18 years+ - NCT06775080RecruitingPhase 2
Testing propranolol before and after surgery for stomach or colon cancer
This trial tests if taking a medicine called propranolol around the time of surgery can improve outcomes for people with stomach or colon cancer that can be removed with an operation. Propranolol is a type of drug that blocks certain stress signals in the body and may help with recovery.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06881628RecruitingPhase 4
Tranexamic acid and vitamin K for bleeding in cirrhosis
This trial tests if giving tranexamic acid and vitamin K by injection can help control bleeding from the upper digestive tract in people with liver cirrhosis. It may offer a way to stop bleeding more quickly.
Tanta, GharbyeaAges 18 years+ - NCT06896409Recruiting
PuraStat and adrenaline vs standard care for upper GI bleeding
This trial tests whether a gel called PuraStat, used together with adrenaline, works better than standard care to stop bleeding in the upper digestive system. It may help people who need an endoscopic procedure to treat non-variceal bleeding.
LleidaAges 18 years+ - NCT06926374Recruiting
Robotic surgery for gastrointestinal and urologic conditions
This trial tests a new robotic surgery system for common operations on the colon, rectum, prostate, kidney, bladder, stomach, esophagus, gallbladder, and hiatal hernia. It may offer a less invasive option for patients who need surgery for these conditions.
Hong KongAges 18–80 - NCT06954077RecruitingPhase 1
BL-M09D1 for advanced gastrointestinal and other solid tumors
This trial tests a new drug, BL-M09D1, for people with advanced or metastatic gastrointestinal or other solid tumors that have stopped responding to standard treatments. The goal is to see if the drug can shrink tumors and how safe it is.
Guangzhou, GuangdongAges 18 years+ - NCT06966232RecruitingPhase 3
Using entecavir to prevent hepatitis B flare-up in gastrointestinal cancer patients
This trial tests whether giving the antiviral drug entecavir before or at the first sign of hepatitis B reactivation can prevent liver problems in gastrointestinal cancer patients who are inactive hepatitis B carriers and are starting chemotherapy or immunotherapy.
Guangzhou, GuangdongAges 18–75 - NCT07067385RecruitingPhase 1
Personalized mRNA vaccine for advanced GI cancers
This trial tests a personalized mRNA vaccine designed to teach your immune system to attack your specific tumor. It is for people with advanced gastrointestinal cancers who have exhausted other options.
Shanghai, SHAges 18 years+ - NCT07124351RecruitingPhase 4
Using a special dye to see cancer during surgery
This trial tests a drug called pafolacianine (CYTALUX) that makes cancer cells glow during surgery. It may help doctors see and remove more cancer from the stomach, esophagus, or appendix. You take the drug before surgery, and a special camera shows the glowing cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT07171203RecruitingPhase 1
Imatinib and fampridine before surgery for KIT-mutant GIST
This trial tests whether combining two oral medications, imatinib and fampridine, before surgery can shrink GIST tumors that have a specific KIT gene mutation. The goal is to improve surgical outcomes and potentially reduce the risk of the tumor coming back.
La Jolla, CaliforniaAges 18 years+ - NCT07211386Recruiting
Nerve block for severe cancer-related abdominal pain
This study tests whether a nerve block, called an erector spinae plane block, can reduce severe abdominal pain in people with gastrointestinal cancer who come to the emergency room. If you have cancer in your digestive system and are in pain that isn't controlled, this trial may help.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 481 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.