Clinical trials
Gender clinical trials
Below are recruiting gender clinical trials, each written for real people, not researchers. We’re tracking 106 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06015776Recruiting
Heart cell signals after menopause
This trial studies how heart cells communicate after menopause. Researchers are looking at a chemical signal called purinergic signaling during heart surgery.
Boston, MassachusettsAges 30–88 - NCT06247267Recruiting
Hormone replacement therapy in military members
This study is looking at how sex hormone replacement therapy affects active-duty military members and their families. It aims to understand the effects in people with low testosterone or those receiving gender-affirming hormones.
Bethesda, MarylandAges 18–65 - NCT06343844Recruiting
Heart attack recovery differences between men and women
This study looks at how men and women recover differently after a first heart attack. By comparing heart function over time, researchers hope to find better ways to treat each gender.
AngersAges 18 years+ - NCT06367764Recruiting
PTSD treatment study for sexual and gender minorities
This study compares different treatments for PTSD specifically designed for people who are sexual or gender minorities. It aims to find which approach works best for this community, and you can join sessions in person or by video.
Palo Alto, CaliforniaAges 18 years+ - NCT06428669RecruitingPhase 4
Nitropaste for chest masculinizing surgery
This study tests if applying nitropaste to the chest before surgery improves blood flow to the nipple grafts, which may help them heal better. It is for people having chest masculinizing surgery with a specific technique called double incision and free nipple grafting.
Charlottesville, VirginiaAges 18 years+ - NCT06439290Recruiting
Voice Changes After Vocal Cord Surgery
This study looks at how different types of voice surgery affect the voice. Researchers will record and analyze voices before and after surgery to understand the results better.
Ghent, East-FlandersAges 18–70 - NCT06487754Recruiting
Chronic pelvic pain in trans people on testosterone therapy
This study explores why some trans masculine people develop new or worsening pelvic pain after starting testosterone therapy. Researchers want to understand your experience through interviews.
Saint-Martin-d'HèresAges 18 years+ - NCT06530992Recruiting
Tucking and semen quality in adult trans women
This study looks at whether tucking affects semen quality in adult transgender women who are about to start or are on hormone therapy. The results could help patients understand how tucking might impact their fertility options.
InnsbruckAges 18–50 - NCT06591897Recruiting
How does aging affect the liver differently by sex?
This study looks at how aging affects the liver differently in men and women. You would have tests to check your liver health, and no medications or treatments will be given.
Hangzhou, ZhejiangAges 18–80 - NCT06608979Recruiting
Trauma screening and violence prevention for women in addiction treatment
This study offers trauma screening and a program to help prevent interpersonal violence for women who are currently receiving treatment for substance use. It aims to understand how these services can improve safety and well-being.
Greenville, South CarolinaAges 18 years+ - NCT06639763Recruiting
Erectile aid use after gender-affirming surgery
This study looks at how transgender men and their partners use erectile aids after phalloplasty or metoidioplasty. It hopes to improve sexual health and satisfaction after surgery.
Ghent, East-FlandersAges 18 years+ - NCT06639776Recruiting
Sexual function after erectile implant in transgender people
This study looks at how well erection prostheses (implants that help with erections) work for transgender people after phalloplasty surgery. It aims to understand sexual functioning for both you and your partner.
Ghent, East-FlandersAges 18 years+ - NCT05489965Recruiting
Looking at voice outcomes in people using a TEP after laryngectomy
This study follows people who have had their voice box fully removed (total laryngectomy) and who use a TEP (a specific type of voice device). It aims to understand whether voice results differ between men and women.
La Jolla, CaliforniaAges 18 years+ - NCT06783400Recruiting
Relationship Health Study in Lilongwe and Balaka
This study looks at the SASA! Together program, which aims to improve relationships and reduce violence in communities. If you are a man or woman aged 18-49 and have ever been in a romantic partnership, you may be able to join.
BlantyreAges 18–49 - NCT06832514RecruitingPhase 4
Gender and immune response to meningitis B vaccine
This study tests how well the meningitis B vaccine works in transgender and cisgender people. It aims to understand if sex and gender affect immune responses.
GhentAges 18–50 - NCT06853314Recruiting
PrEP for women with past legal or child welfare involvement
This trial tests a program to help women who have had contact with the criminal legal system or child protective services get and stay on PrEP (a daily pill that prevents HIV). The study also looks at how to support women who have experienced intimate partner violence or risky drinking.
New York, New YorkAges 18 years+ - NCT06939257Recruiting
Hormone therapy and pain in gender diverse adults
This study looks at how gender-affirming hormone therapy affects pain in gender diverse (GM) adults. It may help understand whether these hormones change how you feel pain.
Kansas City, KansasAges 18–50 - NCT06969326RecruitingPhase 3
Estrogen cream after hysterectomy for transgender men
This study tests whether using a topical estrogen cream after hysterectomy surgery can help transgender men have a better recovery. Participants will be randomly assigned to use the cream or not, and researchers will follow up by text message.
Providence, Rhode IslandAges 18 years+ - NCT07109596Recruiting
Frailty prediction for older hospital patients
This study looks at how different factors—like health, mental well-being, and social support—work together to predict frailty in older adults. The goal is to better understand frailty in men and women, which may help doctors provide more personalized care.
RomaAges 56 years+ - NCT07111026Recruiting
Heart health program for farmworker women
This study tests whether community health workers can help farmworker women improve their heart health. It may be a good fit if you work in farming and want to learn how to take better care of your heart.
Ellenton, GeorgiaAges 18–50 - NCT07196930Recruiting
Valvular heart disease in women registry
This study is a registry that collects data on women with valvular heart disease (heart valve problems). It aims to better understand how these conditions affect women and improve their care. You may join if you have a heart valve condition and are treated at a participating center.
AswānAges 18 years+ - NCT05787470Recruiting
How hormone levels affect pain signals
This study looks at how hormone treatment and hormone levels may change how the body produces pain signals. It may help researchers better understand pain differences between people with different hormone levels and treatment histories.
Birmingham, AlabamaAges 18–65 - NCT02781519RecruitingPhase 1
Study how THC affects men and women who have used cannabis before
This Phase 1 study tests how delta-9 THC (the main active ingredient in cannabis) affects healthy adults, and whether the effects differ by gender. It may help researchers understand risks and responses to THC, which could guide safer use and future treatments.
West Haven, ConnecticutAges 18–55
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Common questions
- Are there clinical trials for gender?
- Yes. Clin2 currently lists 106 recruiting gender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.