Clinical trials
Gender clinical trials
Below are recruiting gender clinical trials, each written for real people, not researchers. We’re tracking 102 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06939257Recruiting
Hormone therapy and pain in gender diverse adults
This study looks at how gender-affirming hormone therapy affects pain in gender diverse (GM) adults. It may help understand whether these hormones change how you feel pain.
Kansas City, KansasAges 18–50 - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT06853314Recruiting
PrEP for women with past legal or child welfare involvement
This trial tests a program to help women who have had contact with the criminal legal system or child protective services get and stay on PrEP (a daily pill that prevents HIV). The study also looks at how to support women who have experienced intimate partner violence or risky drinking.
New York, New YorkAges 18 years+ - NCT06832514RecruitingPhase 4
Gender and immune response to meningitis B vaccine
This study tests how well the meningitis B vaccine works in transgender and cisgender people. It aims to understand if sex and gender affect immune responses.
GhentAges 18–50 - NCT06807580RecruitingPhase 2
Adding progesterone to gender-affirming hormone therapy: a study for transgender women
This study tests whether adding progesterone to your current hormone therapy helps transgender women feel better and more satisfied with their treatment. It might be a good fit if you've been on hormones for at least 6 months and haven't used progesterone before.
Atlanta, GeorgiaAges 18–60 - NCT06800053Recruiting
Support for LGBTQ+ cancer patients and caregivers
This study tests the FOCUS program, a support program designed for sexual and gender minority (LGBTQ+) cancer patients and their unpaid caregivers. It aims to help patients and caregivers cope with cancer through education and emotional support.
Detroit, MichiganAges 18–100 - NCT06783400Recruiting
Relationship Health Study in Lilongwe and Balaka
This study looks at the SASA! Together program, which aims to improve relationships and reduce violence in communities. If you are a man or woman aged 18-49 and have ever been in a romantic partnership, you may be able to join.
BlantyreAges 18–49 - NCT06247267Recruiting
Hormone replacement therapy in military members
This study is looking at how sex hormone replacement therapy affects active-duty military members and their families. It aims to understand the effects in people with low testosterone or those receiving gender-affirming hormones.
Bethesda, MarylandAges 18–65 - NCT06758986Enrolling by invitation
Gender and shoulder pain study
This study looks at whether gender affects shoulder pain from subacromial impingement. It may help tailor future treatments.
Kırşehir, MerkezAges 18–65 - NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06586151Recruiting
HIV prevention program for gender-diverse teens
This study tests a text-message program to help prevent HIV in teens who are transgender, non-binary, or gender-diverse. It aims to see if the program can support healthy choices and reduce risk.
San Clemente, CaliforniaAges 14–18 - NCT06576193Recruiting
Healthy relationships for young parents
This study is testing a program to help young parents build healthy relationships. You will be asked to participate in three interviews over one year to see how the program works.
Camden, DelawareAges 14–21 - NCT06502353Recruiting
Plexaa before gender-affirming mastectomy
This trial tests a product called Plexaa, which is applied before surgery to help prepare the skin and improve healing. It is for transgender or non-binary people having a specific type of mastectomy (breast removal) for gender affirmation.
Palo Alto, CaliforniaAges 18 years+ - NCT06436560Enrolling by invitation
Support for transgender and non-binary people seeking vaginoplasty
This study tests a virtual peer support program for transgender and non-binary people who are planning to have vaginoplasty. It aims to see if talking with a trained peer can help with the process.
San Francisco, CaliforniaAges 18 years+ - NCT06343844Recruiting
Heart attack recovery differences between men and women
This study looks at how men and women recover differently after a first heart attack. By comparing heart function over time, researchers hope to find better ways to treat each gender.
AngersAges 18 years+ - NCT06226818Recruiting
Support for women experiencing sexual or domestic violence
This trial compares two types of care—women's centers versus traditional health centers—to see which better supports the mental and physical health of women who have faced sexual or domestic violence. It aims to find the best way to help women heal.
DijonAges 18 years+ - NCT05649306Recruiting
Surveys for coping and sexual health in bladder cancer survivors
This study asks women with bladder cancer to complete questionnaires about how they cope emotionally and about sexual health. It may help researchers understand what support survivors need and improve survivorship care.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40 - NCT05869552Recruiting
Screening and support to reduce suicide risk in young adults
This trial tests a support program in primary care for sexual and gender diverse young adults who screen positive for suicide risk. The goal is to help prevent suicidal thoughts and actions by offering structured support—especially through trusted people in your life.
Pittsburgh, PennsylvaniaAges 18–24 - NCT04440761Recruiting
Registry for people with MINOCA heart-related chest pain
This is a research registry that collects information from people diagnosed with MINOCA (a specific type of heart-related injury). It may help researchers better understand causes and outcomes for this condition.
LondonAges 16 years+ - NCT06015776Recruiting
Heart cell signals after menopause
This trial studies how heart cells communicate after menopause. Researchers are looking at a chemical signal called purinergic signaling during heart surgery.
Boston, MassachusettsAges 30–88 - NCT05927350Recruiting
Transgender and gender-diverse teens research participation
This study is looking for teens ages 15 to 21 who identify as transgender or gender-diverse (their gender identity is different from the sex they were assigned at birth). Your participation may help researchers better understand and support transgender and gender-diverse youth.
Richmond, VirginiaAges 15–21 - NCT05897086Enrolling by invitationPhase 2/Phase 3
PEG-based help during phalloplasty nerve repair
This trial tests whether adding a substance called polyethylene glycol (PEG) helps nerves heal better during phalloplasty. It may improve how well the repaired nerves work after surgery for some people.
Nashville, TennesseeAges 18 years+ - NCT05794321RecruitingPhase 2
IV tranexamic acid during gender-affirming chest surgery
This Phase 2 study tests whether giving tranexamic acid through a vein during gender-affirming mastectomy can safely reduce bleeding. It may help lower blood loss and related complications during surgery.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for gender?
- Yes. Clin2 currently lists 102 recruiting gender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.