Clinical trials
Gender clinical trials
Below are recruiting gender clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05436106Recruiting
Reducing stress with a behavioral program for Black gender minority women
This trial tests a behavior-based program meant to help lower stress. It is designed for Black gender minority women who were assigned male at birth.
Atlanta, GeorgiaAges 18–99 - NCT01072825Recruiting
Study for adults with gender incongruence not on hormone therapy
This study focuses on adults (18+) who are transgender and have not started hormone treatment yet. It aims to better understand gender incongruence and support care planning.
GhentAges 18 years+ - NCT06226818Recruiting
Support for women experiencing sexual or domestic violence
This trial compares two types of care—women's centers versus traditional health centers—to see which better supports the mental and physical health of women who have faced sexual or domestic violence. It aims to find the best way to help women heal.
DijonAges 18 years+ - NCT06083766Recruiting
Hormone Therapy Effects on Metabolism in Transgender Adults
This study looks at how long-term gender-affirming hormone therapy affects your body's metabolism and energy use. Researchers want to understand these changes better to improve care for transgender and gender-diverse people.
Rochester, MinnesotaAges 18–40 - NCT05927350Recruiting
Transgender and gender-diverse teens research participation
This study is looking for teens ages 15 to 21 who identify as transgender or gender-diverse (their gender identity is different from the sex they were assigned at birth). Your participation may help researchers better understand and support transgender and gender-diverse youth.
Richmond, VirginiaAges 15–21 - NCT05869552Recruiting
Screening and support to reduce suicide risk in young adults
This trial tests a support program in primary care for sexual and gender diverse young adults who screen positive for suicide risk. The goal is to help prevent suicidal thoughts and actions by offering structured support—especially through trusted people in your life.
Pittsburgh, PennsylvaniaAges 18–24 - NCT06586151Recruiting
HIV prevention program for gender-diverse teens
This study tests a text-message program to help prevent HIV in teens who are transgender, non-binary, or gender-diverse. It aims to see if the program can support healthy choices and reduce risk.
San Clemente, CaliforniaAges 14–18 - NCT06502353Recruiting
Plexaa before gender-affirming mastectomy
This trial tests a product called Plexaa, which is applied before surgery to help prepare the skin and improve healing. It is for transgender or non-binary people having a specific type of mastectomy (breast removal) for gender affirmation.
Palo Alto, CaliforniaAges 18 years+ - NCT07133321Enrolling by invitation
Helping husbands support safe hospital births
This trial tests whether a set of programs can help more women give birth in a health facility. It focuses on husbands to encourage their wives to deliver at a hospital or clinic.
Arba Minch, Southern Nations Nationalities Regional StateAges Any age - NCT06576193Recruiting
Healthy relationships for young parents
This study is testing a program to help young parents build healthy relationships. You will be asked to participate in three interviews over one year to see how the program works.
Camden, DelawareAges 14–21 - NCT07226401Recruiting
Virtual village for young parents
This study tests a virtual support program for young parents, looking at whether it helps with parenting skills and well-being. If you join, you'll take part in online group sessions with other young parents.
Durham, North CarolinaAges 16–21 - NCT06758986Enrolling by invitation
Gender and shoulder pain study
This study looks at whether gender affects shoulder pain from subacromial impingement. It may help tailor future treatments.
Kırşehir, MerkezAges 18–65 - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT04028219Recruiting
Study for people transitioning gender-affirming care
This study looks at people who are preparing to start gender-affirming hormone treatment. It may help researchers understand what support is needed before hormones begin.
Frankfurt am Main, HesseAges 18 years+ - NCT04064671Recruiting
Study of a specific erectile implant after sex reassignment surgery
This study looks at surgical outcomes after placing the Zephyr ZSI 475 FTM inflatable penile implant in people who had female-to-male (transmasculine) sex reassignment surgery. It may help improve how well this specific implant works and how patients do after surgery.
Ghent, Oost-VlaanderenAges 18–100 - NCT04440761Recruiting
Registry for people with MINOCA heart-related chest pain
This is a research registry that collects information from people diagnosed with MINOCA (a specific type of heart-related injury). It may help researchers better understand causes and outcomes for this condition.
LondonAges 16 years+ - NCT04596592Recruiting
Puberty blockers and estradiol effects on heart health
This study looks at how puberty blockers and then estradiol (estrogen) may affect heart and metabolism health in teens. It may help doctors understand risks and benefits for transgender youth starting gender-affirming hormone care.
Aurora, ColoradoAges 13–16 - NCT04704271RecruitingPhase 1
Study on THC effects in people with past cannabis use
This Phase 1 study looks at how THC (the main mind-altering ingredient in cannabis) affects healthy volunteers shortly after use. It focuses on differences between people and includes those who have used cannabis before.
West Haven, ConnecticutAges 18–55 - NCT05097820Recruiting
Study of silicone gel testicular implants after placement
This is an observational study that follows people who receive silicone gel-filled testicular implants. It aims to collect real-world information about safety and healing to help improve future care.
Ghent, East-FlandersAges birth–110 years - NCT05141591Recruiting
Anxiety before ENT surgery and opioid use after surgery
This trial looks at whether people’s anxiety before ear, nose, and throat (ENT) surgery affects how much pain medicine (opioids) they need after surgery. It may help doctors better plan pain control based on anxiety level and possibly gender-related patterns.
Vienna, State of ViennaAges 18 years+ - NCT05649306Recruiting
Surveys for coping and sexual health in bladder cancer survivors
This study asks women with bladder cancer to complete questionnaires about how they cope emotionally and about sexual health. It may help researchers understand what support survivors need and improve survivorship care.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05883553Recruiting
Erection device vs cover after gender-affirming penis surgery
This trial compares two options to help people who have had phalloplasty have penetrative sex: an erection prosthesis (an implanted device) versus an epithesis (a removable cover/prosthetic). It aims to see which option works better and is acceptable for restoring sensation, function, and sexual penetration.
Ghent, East-FlandersAges 18 years+ - NCT05954364Recruiting
Study of advanced treatments for psoriatic arthritis based on sex and gender
This study looks at how well advanced treatments work for people with psoriatic arthritis, and whether results differ for sex and gender. You may be eligible if your psoriatic arthritis is active and you are planning to start an advanced treatment for symptoms in the joints and surrounding areas.
Toronto, OntarioAges 18 years+ - NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+
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Common questions
- Are there clinical trials for gender?
- Yes. Clin2 currently lists 105 recruiting gender studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gender trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gender trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.