Clinical trials
General Anxiety Disorder clinical trials
Below are recruiting general anxiety disorder clinical trials, each written for real people, not researchers. We’re tracking 132 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05569018Recruiting
Spanish blended group therapy for anxiety and depression symptoms
This study tests whether a group therapy program delivered in both online and in-person formats can reduce emotional symptoms like anxiety and depression. If you qualify, you may be assigned to receive this structured group treatment during the study period.
Castellon, CastellónAges 18 years+ - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT07219992Recruiting
Parent-led treatment for teens with anxiety
This study tests a program that helps parents learn ways to support their teenager who has an anxiety disorder, like social anxiety or panic attacks. The goal is to see if this parent-based approach can reduce the teen's anxiety without the teen needing to attend therapy sessions.
New Haven, ConnecticutAges 14–17 - NCT05232032RecruitingPhase 2
Brain scan and medication study for avoiding versus approaching
This Phase 2 study looks at how a medication affects brain activity and real-life mood or anxiety behaviors. It includes people with major depression or several anxiety disorders and also healthy volunteers, using questionnaires, a smartphone, and brain imaging.
Belmont, MassachusettsAges 18–45 - NCT06297200Recruiting
Ultrasound treatment for complex back pain patients
This study tests a new, non-invasive ultrasound treatment for people with long-term back pain who also have opioid use disorder and anxiety. It aims to see if this gentle brain stimulation can reduce pain and improve quality of life.
Roanoke, VirginiaAges 18–65 - NCT07292610Recruiting
Nut study for young university students
This trial tests whether eating nuts regularly can improve mental health in young adults. If you are a university student aged 18-25, you may be able to join.
Cuenca, CuencaAges 18–24 - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT07315516RecruitingPhase 2
Sleep and stress supplement study
This study tests a new supplement to help with sleep and stress. It is for adults who feel stressed and have sleep problems, but are otherwise healthy.
BrisbaneAges 18 years+ - NCT07818876Recruiting
Computer training to help teens with anxiety
This study tests a computer-based training program that aims to change how anxious teens interpret situations. It could help reduce anxiety by retraining the brain's automatic responses.
Denver, ColoradoAges 10–17 - NCT05921773Recruiting
Near-infrared brain monitoring and training for anxiety
This study tests whether using a painless light-based brain monitor and “neurofeedback” training can help track and reduce symptoms in people with generalized anxiety disorder. If you are eligible, you would receive sessions during the study and be able to communicate in Chinese.
TaipeiAges 18 years+ - NCT07145307Recruiting
App for teens with anxiety: a feasibility trial
This trial tests if a smartphone app can help teenagers with anxiety when used alongside their regular therapy. It aims to see if the app is helpful and easy to use for teens getting exposure therapy.
StavangerAges 13–18 - NCT05837104RecruitingPhase 2
Magnesium and vitamin B6 for early bipolar depression
This Phase 2 trial tests whether magnesium plus vitamin B6 can reduce depressive symptoms in people who are newly diagnosed with bipolar I disorder. It also checks for safety over a short, 4-week treatment period.
Belmont, MassachusettsAges 18–50 - NCT06442423RecruitingPhase 1
Psilocybin study for people with psychiatric symptoms
This trial tests if psilocybin, a substance found in certain mushrooms, can help people with various mental health symptoms that affect daily life. You would take a single dose in a supervised setting and be monitored for changes in your mood and well-being.
New Haven, ConnecticutAges 18 years+ - NCT07383467Recruiting
Single session help for teens with anxiety or depression
This trial offers a one-time digital self-help program for Hong Kong teens aged 12 to 17 who feel anxious or down. It aims to see if a single session can make a difference.
Hong KongAges 12–17 - NCT07340281Recruiting
Exercise and biomarkers for anxiety
This study looks at how exercise affects certain markers in the body in people with anxiety disorders. You may be able to join if you are currently sedentary and have generalized anxiety, social anxiety, or panic disorder.
New York, New YorkAges 18–50 - NCT06273904Recruiting
Focused ultrasound to help manage anxiety
This trial tests whether focused ultrasound can help people with anxiety disorders better manage their symptoms. It involves brain stimulation and recording sessions to see how the treatment works.
Charleston, South CarolinaAges 18–65 - NCT05447689Recruiting
Group mind-body skills for anxious graduate students
This trial offers a weekly group program teaching mind-body skills to help reduce anxiety. It’s for graduate students who screen as having moderate or higher anxiety and can attend meetings regularly.
White Plains, New YorkAges 18 years+ - NCT04824105Recruiting
Therapy for anxious coping using brain stimulation
This study tests a treatment approach aimed at helping people manage anxiety and related conditions by changing brain activity. It may help if you’re currently trying to get mental health treatment and meet their specific safety rules.
Charleston, South CarolinaAges 18–65 - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT06635486Recruiting
Mental health support for Venezuelans in Lima
This study offers mental health support to Venezuelan adults living in Lima who are feeling anxious, depressed, or have experienced trauma. It will check if you have signs of depression, anxiety, or post-traumatic stress and provide help if you do.
LimaAges 18 years+ - NCT05788302Recruiting
Studying prolonged exposure for PTSD and how it helps
This trial studies how a therapy called “prolonged exposure” works for people with post-traumatic stress disorder (PTSD). You may be able to join if you have PTSD, are interested in starting prolonged exposure, and meet other safety and participation rules.
Boston, MassachusettsAges 18 years+ - NCT05877885Recruiting
Digital treatment for low motivation in older adults with depression
This study tests a digital therapy to improve apathy (feeling unmotivated or “checked out”) in people age 60+ who have depression. It also uses brain imaging (MRI) and questionnaires to see whether the treatment helps brain function linked to motivation.
Orlando, FloridaAges 60 years+ - NCT06226155Recruiting
HIV prevention support for pregnant women in Zimbabwe
This study in Zimbabwe tests a program to help pregnant women start and stay on PrEP (medication that prevents HIV). It aims to make PrEP easier to use during pregnancy for women who are at risk of HIV.
HarareAges 15–55
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Common questions
- Are there clinical trials for general anxiety disorder?
- Yes. Clin2 currently lists 132 recruiting general anxiety disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general anxiety disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general anxiety disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.