Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,802 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05040464RecruitingPhase 3
Azathioprine or methotrexate added to adalimumab for Crohn’s
This trial compares two medicine options (azathioprine vs methotrexate) when added to adalimumab to treat active Crohn’s disease. It may help determine which add-on works better for people whose Crohn’s is still active despite standard treatments or who can’t take them.
AmiensAges 18 years+ - NCT05043870RecruitingPhase 4
Testing medicines that calm the immune system in kids with Crohn’s
This trial studies a combination of immune-suppressing treatments for children with Crohn’s disease that is not well controlled. It may help reduce inflammation and improve symptoms if you meet the study’s disease-activity and safety requirements.
Shanghai, Shanghai MunicipalityAges 6–18 - NCT05056740Recruiting
Inflammatory markers for CNS autoimmune disease diagnosis
This trial studies whether certain inflammatory biomarkers in blood and spinal fluid can help diagnose autoimmune diseases affecting the brain and spinal cord. It may help people who are undergoing testing for white matter lesions.
NiceAges Any age - NCT05059158Recruiting
Study how the brain clears amyloid in Alzheimer’s
This trial studies how the brain removes amyloid-β, a protein linked to Alzheimer’s disease. It may help researchers understand what’s happening in people with mild memory impairment or Alzheimer’s, and guide better treatments in the future.
München, BavariaAges 50–85 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT05067348RecruitingPhase 2
Tocilizumab for generalized myasthenia gravis symptoms
This trial tests whether tocilizumab can improve symptoms and safety in people with generalized myasthenia gravis (MG) who already take standard MG treatments. It may help if your weakness is still significant despite current therapy.
Beijing, Beijing MunicipalityAges 18–80 - NCT05067764Recruiting
Aponeurectomy for reducing Dupuytren’s disease return rate
This study looks at whether a specific hand/cord procedure called aponeurectomy can lower how often Dupuytren’s disease comes back within 2 years. You might be offered surgery and then followed to see how well your symptoms and tightness improve and how often they return.
PessacAges 18 years+ - NCT05070013Recruiting
Brain stimulation to improve sleep in people with Parkinson’s disease
This study tests an adaptive brain stimulation device to help restore better sleep in people with Parkinson’s disease. You may be eligible if your Parkinson’s motor symptoms are severe despite best medical treatment and you are already being considered for a specific deep brain stimulation surgery.
Omaha, NebraskaAges 18–80 - NCT05077579Recruiting
Alzheimer’s scan study for people with higher body weight
This study uses brain scans (MRI and two special PET scans) to see how Alzheimer’s-related changes show up in people who are overweight or obese, with different blood-sugar and insulin patterns. It may help researchers understand whether body weight and metabolism affect early Alzheimer’s markers in the brain.
St Louis, MissouriAges 40–60 - NCT05077618Recruiting
Teeth bacteria study in seniors with and without Alzheimer’s
This study looks at the bacteria in the mouth (periodontal microbiota) to see whether they differ between seniors with Alzheimer’s disease and seniors without it. You may be asked for a sample from your gums/teeth and background health information.
Nice, CHU de NICEAges 18–90 - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT05089227RecruitingPhase 2
Long-term apixaban to prevent clots in autoimmune hemolytic anemia
This Phase 2 trial tests whether taking long-term apixaban (a blood thinner) can prevent venous blood clots in people with autoimmune hemolytic anemia (AIHA). It may help reduce the risk of dangerous clotting events if you meet safety and risk criteria.
DijonAges 18 years+ - NCT05093335RecruitingEarly Phase 1
PET scan test for CXCR4 in many relapsed cancers
This early study tests a new PET scan tracer (a radioactive imaging agent) that may light up a cell marker called CXCR4 in certain blood and solid tumor cancers. It may help doctors see where cancers are and how much CXCR4 they have, which could guide future treatments.
New York, New YorkAges 18 years+ - NCT05099874Recruiting
Computer training to improve attention in sickle cell disease
This trial tests whether a computer-based “attention control” training program can improve attention and daily functioning in children with sickle cell disease. To join, you must meet certain criteria and also pass an initial attention screening test during the study.
Washington D.C., District of ColumbiaAges 8–16 - NCT05112549RecruitingPhase 1
PD-1 antibody placed into brain fluid for metastatic cancer
This early-phase study tests a PD-1 antibody delivered directly into the brain fluid (intrathecal space) to treat metastatic solid tumors that have spread to the lining around the brain/spinal cord (leptomeningeal disease). It aims to see whether this approach can better control cancer in that area and whether it’s safe.
BonnAges 18 years+ - NCT05113095Recruiting
Survey of Darvadstrocel in Crohn’s with fistulas
This is a survey study in people with Crohn’s disease who have complex perianal fistulas and have already received Darvadstrocel. It aims to understand how patients are doing after treatment and gather real-world feedback.
Tokyo, TokyoAges 20 years+ - NCT05114850Recruiting
Follow-up study for people treated with TricValve
This study looks back at patients who were successfully treated with TricValve bicaval valve devices and then follows up with their outcomes. You might join if you (or your legal guardian) agree to be included.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT05120934RecruitingPhase 2
Two medicine doses to reduce ILD cough
This Phase 2 study tests whether two different doses of duloxetine and amitriptyline can reduce coughing caused by interstitial lung disease (ILD). If you have had a long-lasting ILD-related cough despite stable ILD treatment, this trial may help find a better way to control your cough.
Rochester, MinnesotaAges 18–75 - NCT05122962Recruiting
MRI study of heart rhythm and exercise capacity after congenital surgery
This study looks at how blood flow and heart rhythm may affect exercise ability in people born with certain heart defects that have been repaired or treated. It uses a specialized heart MRI and ultrasound measurements to better understand these problems and their causes.
Rochester, MinnesotaAges 18 years+ - NCT05124249Recruiting
Imaging tests to evaluate clogged heart arteries
This study looks at how well special heart imaging and pressure-based tests can evaluate coronary artery disease (clogged heart arteries). If you had testing for suspected heart artery disease, the study may help doctors compare how these measurements work.
GwangjuAges 18 years+ - NCT05134311Recruiting
3D ultrasound check for blood-flow problems in wound care
This study tests whether a 3D ultrasound scan can better assess blood-flow problems that may affect healing in the wound clinic. If you’re already scheduled for an ultrasound evaluation at the wound center, the trial may use an additional 3D ultrasound approach to help doctors understand your circulation.
Lake Success, New YorkAges 18 years+ - NCT05136222Recruiting
Testing a night breathing machine setting for muscle-nerve disease
This study helps find the best night-time settings for a non-invasive breathing support device (a machine that helps breathing without a tube). It may help people with motor neurone disease start long-term breathing support more comfortably and effectively.
AdelaideAges 18 years+ - NCT05147779RecruitingPhase 1
Stem cell treatment safety study for multiple bladder and sexual conditions
This Phase 1 trial tests whether lab-grown stem cells made from umbilical-cord tissue are safe in people with Peyronie’s disease, erectile dysfunction, or interstitial cystitis. It may help by showing whether this approach is tolerated and safe, before larger studies test how well it works.
St John'sAges Any age - NCT05151562Recruiting
Music therapy for people with early Alzheimer’s or memory loss
This trial studies whether music therapy can improve symptoms and well-being in people with early Alzheimer’s disease or mild memory problems. You may take part in music sessions and likely be screened with MRI, so the study checks safety for scans.
Baltimore, MarylandAges 18–89
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,802 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.