Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01799915Recruiting
Study of causes and progression of synuclein-related nerve conditions
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
Boston, MassachusettsAges 18 years+ - NCT01140789Recruiting
Study comparing people with and without bowel inflammation
This study looks at people with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) and compares them with people without it. Researchers want to understand differences that may help explain or better detect the disease.
Hong KongAges 18 years+ - NCT00455104Recruiting
Fabry disease registry for Canadians and eligible adults
This study is a national registry that collects health and medical information from people with Fabry disease. It helps researchers better understand the condition and plan future care and studies.
Calgary, AlbertaAges 5–85 - NCT00006150Recruiting
Understanding Hyper-IgE Syndrome: Natural History and Genetics
This study follows people with or suspected Hyper-IgE syndrome (a rare immune disorder causing repeated infections and skin problems) to understand how the condition develops, how best to manage it, and which genes are involved. Researchers also welcome healthy relatives of patients to help identify genetic patterns.
Bethesda, MarylandAges 1 month–120 years - NCT01568697Recruiting
Studying gum disease in people with immune and genetic differences
This study looks at how mouth bacteria and the immune system may work together to cause gum disease (periodontitis), especially in people with certain genetic immune problems. It may help researchers understand what drives severe gum disease and how to better monitor or treat it in the future.
Bethesda, MarylandAges 7–100 - NCT01341327Recruiting
Study of treatment choices for left main artery narrowing
This observational study looks at people with a significantly narrowed “left main” heart artery and records treatment decisions and follow-up outcomes. It may help doctors better understand which care approaches work best for this condition in real-world practice.
ShanghaiAges 18 years+ - NCT00077909Recruiting
Study of Lung Proteins in Patients With Pneumonia
This research study examines proteins in fluid collected from your lungs during a breathing tube procedure (bronchoscopy) to better understand pneumonia. By studying these proteins, researchers hope to improve how doctors diagnose and treat lung infections.
Bethesda, MarylandAges 3–99 - NCT00260585Recruiting
Esophageal risk and tissue registry study
This study collects information and, if you already need blood tests or procedures, may take extra small tissue samples (biopsies) to better understand esophageal-related conditions. It may help researchers learn about risk and future management for people with certain esophagus or reflux-related diagnoses.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT01805869Recruiting
Teeth removal study using leftover tissue for research
This study looks at people who need wisdom tooth (third molar) removal and collects the leftover tissue after extraction. The goal is to use these samples to help dental research, while making sure the procedure can be done safely.
Bethesda, MarylandAges 16–50 - NCT00574327Recruiting
Barrett’s and reflux registry at the Kansas City VA
This study follows people with confirmed Barrett’s esophagus (with or without concerning cell changes) and people who have reflux symptoms, to better understand how these conditions progress. It may help by building a Barrett’s registry so doctors can learn which factors predict worsening over time.
Kansas City, MissouriAges 18 years+ - NCT00004847RecruitingPhase 1
Understanding and Diagnosing Pheochromocytoma and Paraganglioma
This study helps doctors better understand and diagnose pheochromocytoma and paraganglioma—rare tumors that release stress hormones and cause high blood pressure and other symptoms. Researchers will study your medical history, blood and urine tests, imaging scans, and genetic information to improve how these conditions are found and understood.
Bethesda, MarylandAges 3–120 - NCT02000895Recruiting
Studying birth factors in preterm and term mother-infant pairs
This study looks at how biological factors at birth differ between preterm and term babies, and how they relate to the mother and baby together. It may help doctors better understand early-life influences for newborn care.
Miami, FloridaAges Up to 10 years - NCT01633489Recruiting
LAL deficiency patient registry
This study keeps a protected record of people with Lysosomal Acid Lipase (LAL) deficiency to learn more about the condition over time. It may help researchers better understand how patients are doing and support future studies.
Phoenix, ArizonaAges Any age - NCT00032513Recruiting
Genetic study of chronic active Epstein-Barr virus disease
This research study looks for genetic factors that may explain why some people develop severe, long-lasting Epstein-Barr virus (EBV) infection. Researchers will study blood and tissue samples from patients with this rare condition, their healthy relatives, and unrelated volunteers to understand the disease better.
Bethesda, MarylandAges 1–120 - NCT00272883Recruiting
Study genes in congenital muscle weakness
This research study looks at genes and molecules to better understand congenital myopathies (birth-related muscle weakness). It may help explain the cause of symptoms and improve future diagnoses for you and your family.
Boston, MassachusettsAges Any age - NCT00009243Recruiting
Understanding How Strokes Develop: A Research Study
This study follows people who have had or are at risk for stroke to understand what causes strokes and how they develop over time. By participating, you help researchers learn more about stroke prevention and treatment.
Washington D.C., District of ColumbiaAges 18–120 - NCT00470327Recruiting
Study of how interstitial lung disease naturally changes
This study looks at how interstitial lung disease (lung scarring) typically progresses over time. It may help researchers understand what to expect and what changes to watch for.
Chicago, IllinoisAges 18 years+ - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age - NCT01200953Recruiting
Study care after contact with serious infectious germs
This study helps doctors manage people who may have been exposed to, infected with, or are recovering from dangerous infectious germs (including emerging outbreaks). It may help by setting safe evaluation and care steps after these high-risk exposures.
Bethesda, MarylandAges 3–99 - NCT02026843Recruiting
Testing eye fluid markers in chorioretinal eye diseases
This study looks at substances (“biomarkers”) in the clear fluid inside the eye to better understand several eye conditions that affect vision. Your results may help doctors learn how these diseases work and how treatments might be chosen.
Daegu, KyungsangpookdoAges 20–80 - NCT01962415RecruitingPhase 2
Reduced-intensity stem cell transplant for non-cancer disorders
This trial tests whether a gentler (reduced-intensity) conditioning treatment before a stem cell transplant works for non-cancer diseases. It uses specific donor stem cell matches and checks heart, lung, liver, and kidney function to help lower transplant stress while still aiming for benefit.
Pittsburgh, PennsylvaniaAges 2 months–55 years - NCT00091871Recruiting
Understanding familial high eosinophil disease in families
This study follows families with a genetic condition that causes high levels of white blood cells called eosinophils. Researchers want to understand how the disease develops and changes over time to help predict who may get worse and how to treat it better.
Bethesda, MarylandAges 1–100 - NCT01496625Recruiting
Biobank study for retinal diseases and comparison samples
This study collects and stores blood and eye-related medical information to help researchers better understand retinal diseases, including age-related macular degeneration and diabetic retinopathy. Your samples may also be used to compare people with retinal disease to people without it.
Bethesda, MarylandAges 2–120 - NCT00398177Recruiting
Study blood and tissue changes in lymphoma and Hodgkin’s
This study looks at samples of tissue removed during routine procedures to better understand Hodgkin’s disease and non-Hodgkin’s lymphoma. It may help researchers learn more about what these cancers look like in tissue.
Stanford, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,808 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.