Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04496479RecruitingPhase 2
Transplanting donor liver cells near lymph nodes in advanced liver disease
This Phase 2 study tests whether transplanting donor liver cells near lymph nodes can improve outcomes in people with advanced cirrhosis from certain liver conditions. It may help your liver function by adding healthy liver cells, but eligibility is tightly based on your current liver status and other health factors.
Boston, MassachusettsAges 18–70 - NCT04496895Recruiting
Orange peel drink study for reducing body fat
This trial looks at whether a fermented orange peel product can lower body fat in adults. It may help if you have higher body fat and/or fatty liver, and you meet safety and health limits.
Taipei, TaiwanAges 20–65 - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT04504006Recruiting
Tracking surgery choices for lymph node spread in endometrial cancer
This is an observational study that follows people with endometrial cancer who have had surgery to check and remove pelvic (and sometimes paraaortic) lymph nodes. It looks at how different surgical approaches and any added treatment affect local control (keeping cancer from coming back in the pelvis/nearby areas).
Essen, North Rhine-WestphaliaAges 18 years+ - NCT04505618Recruiting
Eye scan study using special imaging for blood-vessel disease
This study uses a detailed eye scan (optical coherence tomography angiography) to look at how blood vessels in the retina are affected. It may help researchers better understand retinal vascular diseases, though some people will be excluded for safety or image-quality reasons.
Baltimore, MarylandAges 18–99 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT04510051RecruitingPhase 1
CAR T cell therapy for IL13Rα2 positive pediatric brain tumors
This Phase 1 study tests a type of immune therapy (CAR T cells) for children with brain tumors that come back or do not respond to standard treatment. The cells are given after chemotherapy that temporarily lowers the body’s immune system, which may help the CAR T cells work better.
Duarte, CaliforniaAges 4–25 - NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT04514445Recruiting
Study of genes in people with bicuspid aortic valve
This study looks for genetic (inherited) differences that may be linked to bicuspid aortic valve (BAV). It includes people with BAV and close family members to help understand why BAV happens and whether genes play a role.
KetteringAges 10–99 - NCT04515251Recruiting
Ultrasound measurements of a key belly artery in healthy kids
This study uses an abdominal ultrasound to measure a blood vessel called the superior mesenteric artery in generally healthy children. It helps researchers understand normal ultrasound measurements, which can improve how doctors interpret scans in the future.
BellinzonaAges 10–15 - NCT04516057RecruitingPhase 3
Tested medicine nabilone for agitation in Alzheimer’s dementia
This Phase 3 trial studies whether nabilone can reduce agitation (restlessness, anger, or difficult behavior) in people with Alzheimer’s dementia. It’s designed for older adults who already have agitation despite standard dementia care.
Calgary, AlbertaAges 55 years+ - NCT04519151RecruitingPhase 2
Pembrolizumab plus lenvatinib for ovarian cancer that returned
This Phase 2 trial tests whether pembrolizumab plus lenvatinib can shrink ovarian cancer that has come back after platinum chemotherapy. You may be eligible if your cancer returned after a certain “time off” from prior treatment and you meet key health and safety requirements.
Ramat GanAges 18 years+ - NCT04518475RecruitingPhase 4
Eltrombopag with rituximab versus eltrombopag alone for ITP
This trial compares two treatment approaches for adults with primary immune thrombocytopenia (ITP), a condition where platelet counts are too low. It looks at whether adding rituximab to eltrombopag helps control ITP better and more safely.
TianjinAges 18–60 - NCT04520126Recruiting
Olive extract for blood vessel and heart function after heart procedures
This trial tests whether an olive extract supplement (Olivomed) improves how your blood vessels, heart, and circulation work. It focuses on people with stable or recently treated coronary heart disease and certain cholesterol patterns.
Athens, AtticaAges 18–70 - NCT04521699Recruiting
CalmiGo stress device to improve heart blood vessel health
This study looks at whether a stress-management device (CalmiGo) can improve blood vessel function and heart disease risk in people recovering from recent heart procedures. You would use the device for 12 weeks and complete questionnaires, blood tests, and a heart-vessel test at the start and end.
Rochester, MinnesotaAges 18 years+ - NCT04522765Recruiting
Tracking daily blood pressure patterns in people at high heart risk
This study measures how your blood pressure changes across the day in people at higher risk of heart and blood vessel disease. It may help researchers understand why blood pressure patterns vary, which could guide better prevention or care.
EdinburghAges 18–90 - NCT04523857RecruitingPhase 2
Abemaciclib and hydroxychloroquine after breast cancer relapse risk
This Phase 2 trial tests whether abemaciclib plus hydroxychloroquine can kill tiny “leftover” cancer cells in the bone marrow after standard breast cancer treatment. It may help lower the chance of cancer coming back by targeting minimal residual disease.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04524338Recruiting
At-home brain stimulation study for dementia
This study looks at using a home device that delivers a mild electrical current to the brain (“tDCS”) over time in people with Alzheimer’s disease or other dementias. It aims to learn whether this approach is safe and potentially helpful for symptoms.
Montreal, QuebecAges 50–100 - NCT04525144RecruitingPhase 2
Test EGb 761 for mild memory loss with brain blood vessel disease
This trial studies EGb 761 to see if it can improve symptoms in people with mild cognitive impairment (early memory/thinking changes) who also have signs of brain blood vessel disease. It may help by targeting the brain changes seen on scans.
SingaporeAges 45–85 - NCT04526353RecruitingPhase 2
Oxybutynin for young boys with posterior urethral valves
This trial tests whether early use of oxybutynin can improve bladder and urine behavior in very young boys with posterior urethral valves. It is mainly for babies whose bladder tests show problems even after valve surgery.
BordeauxAges 3 months–6 months - NCT04527705Recruiting
Testing endodontic retreatment in one versus two visits
This study compares doing tooth root-canal retreatment in one visit versus two visits. It’s meant to see which approach leads to better outcomes for teeth with infection at the root tip (apical periodontitis).
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT04528498Recruiting
Embryo health study for IVF using PGT-A testing
This study looks at embryo health using a DNA test called PGT-A for couples having IVF. It may help researchers better understand what the test can and cannot tell about which embryos are healthiest.
North Brunswick, New JerseyAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,808 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.