Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,808 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04854213Recruiting
Study checks radiation effects in colon cancer lung-limited spread
This trial studies how targeted radiation (SBRT) affects cancer biology and immune cells in people with colon cancer that has spread only to a small number of lung nodules. Your tumor tissue will be analyzed to see what changes after treatment.
Naples, NAPOLIAges 18–80 - NCT04855630Recruiting
Sleep and mild exercise program for thinking and memory support
This study tests whether combining better sleep routines with mild exercise can help with memory, concentration, and thinking speed. To do that, you would wear special devices and complete quick at-home and in-person assessments and a small finger-prick blood test.
Miami, FloridaAges 45–80 - NCT04855773Recruiting
Mobile text-message support to help people stay on PrEP
This trial tests whether phone-based (iPhone/Android) text-message support can improve how consistently people use PrEP, an HIV prevention medicine. It may help you stay on track with refills and clinic visits, especially if you’re at higher risk of stopping PrEP.
San Francisco, CaliforniaAges 15 years+ - NCT04856059Recruiting
MRI study for early heart changes in Fabry disease
This study looks at early structural and tissue changes in the heart using a special type of MRI scan in adults with Fabry disease. It may help doctors understand changes earlier and better track heart involvement over time.
Toronto, OntarioAges 18 years+ - NCT04856488RecruitingPhase 3
Lugol’s iodine solution before thyroid surgery for overactive thyroid
This trial tests whether taking Lugol’s iodine solution before thyroid surgery is safe and helpful for people with Graves’ disease or toxic nodular goiter (overactive thyroid). It may be aimed at improving surgical readiness and outcomes by reducing thyroid activity before the operation.
Solna, Stockholm CountyAges 18–75 - NCT04859088Recruiting
Biologics plus partial tube-feeding for Crohn’s disease
This study tests whether starting adalimumab along with partial enteral (tube or drink) nutrition helps control active Crohn’s disease. It may help reduce symptoms and inflammation compared with standard care alone.
Glasgow, ScotlandAges 16 years+ - NCT04861506Recruiting
Clot-removal treatment for blocked blood flow in the leg
This trial tests how safe and effective a clot-removal procedure done through the blood vessels is for people with acute or subacute blocked blood flow in the lower leg. It may help by improving circulation while carefully tracking risks and results.
Hangzhou, ZhejiangAges 18 years+ - NCT04864145Recruiting
Valve procedure trial for severe leaking aortic valve
This trial studies a less invasive heart valve procedure that places a new valve through a catheter, to treat severe leakage of the aortic valve. It may help people who have symptoms or heart enlargement and who are at higher risk for open-heart surgery.
Nanjing, JiangsuAges 60–90 - NCT04871607RecruitingPhase 2
Yttrium antibody plus chemotherapy for hard-to-treat Hodgkin lymphoma
This trial studies a targeted antibody therapy with yttrium, combined with intensive chemotherapy, for adults whose Hodgkin lymphoma did not respond well or came back. It may help by delivering cancer-killing radiation directly to lymphoma cells and preparing the body for treatment after transplant conditioning.
Duarte, CaliforniaAges 18 years+ - NCT04873011RecruitingPhase 1
Quinine in overweight women to change hunger and gut hormones
This early study tests whether quinine affects hunger and digestion-related gut hormones in women who are mildly overweight. It may help researchers understand how the body controls appetite, but it is mainly to check effects and safety.
Leuven, Vlaams-BrabantAges 18–65 - NCT04874064Recruiting
AI blood tests for triple-negative breast cancer after treatment
This study uses a computer (AI) to read results from blood tests to look for signs of remaining triple-negative breast cancer, before and/or after surgery. It may help doctors better detect residual tumor and guide follow-up care.
London, OntarioAges 18 years+ - NCT04876339Recruiting
Sound-based training to improve walking after brain illness
This study tests whether using special sounds (sonification) during gait training can improve walking for people with stroke, Parkinson’s disease, or multiple sclerosis. It may help your walking speed, stamina (fatigue), and overall walking pattern.
PaviaAges Up to 80 years - NCT04882488Recruiting
Testing heart scan measurements in severe aortic valve narrowing
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Bad Oeynhausen, North Rhine-WestphaliaAges 65 years+ - NCT04885985Recruiting
Check a new treatment for blocked leg arteries after procedures
This post-market study follows people with significant below-the-knee artery blockages to see how a treatment performs over time. It may help patients by confirming the safety and ongoing effectiveness of the device used for these leg artery problems.
Beijing, Beijing MunicipalityAges 18–75 - NCT04887623Recruiting
Blood and breathing marker tracking in hospitalized COVID-19
This study follows hospitalized people with recent COVID-19 to see how infection and inflammation markers change over time. It may help doctors better understand what’s happening in the body as breathing problems develop and treatments are given.
Hradec KrálovéAges 18–90 - NCT04891029Recruiting
Early detection testing for uterine or ovarian cancer risk
This study looks for early signs of uterine (endometrial) or ovarian cancer, especially in people with inherited risk. It may help doctors catch problems earlier, when treatment can be more effective.
Montreal, QuebecAges 45–75 - NCT04893564Recruiting
Testing blood DNA after 6 months of Waldenström treatment
This study looks at a blood test called circulating tumor DNA, measured after 6 months of treatment, to see how well it predicts outcomes in people with Waldenström macroglobulinemia. It may help doctors better judge who is responding and who may need treatment adjustments earlier.
AmiensAges 18 years+ - NCT04895436RecruitingPhase 2
Oral venetoclax plus IV obinutuzumab after prior CLL treatment
This trial tests whether adding oral venetoclax together with an IV antibody called obinutuzumab can control CLL when the disease comes back after a specific prior treatment. It also looks closely at side effects to see what changes in “disease activity” and safety to expect.
La Jolla, CaliforniaAges 18 years+ - NCT04896684Recruiting
Study collecting gut health information from adults’ scans
This study is looking at people who need an intestinal scope (endoscopy) for gut symptoms or bowel conditions like IBS, IBD, or possible colorectal cancer. Your results may help doctors better understand these long-term conditions and improve follow-up care.
ToulouseAges 18–99 - NCT04896606RecruitingPhase 1/Phase 2
Matched donor immune therapy for mild to moderate COVID-19
This early-phase study tests immune cells from a matched family donor (made to target the COVID-19 virus) to see if they can help people with mild-to-moderate COVID-19 who are hospitalized and at higher risk for getting sicker. It aims to check safety first and also look for signs of benefit.
Valhalla, New YorkAges 18–65 - NCT04897321RecruitingPhase 1
CAR T therapy for children with B7-H3 solid tumors
This early-phase study tests a lab-made immune therapy (CAR T cells) made from your own cells to treat children’s solid tumors that have a specific marker called B7-H3. It is designed for kids whose cancer has come back or did not respond to standard treatment, aiming to shrink tumors and keep the therapy safe.
Memphis, TennesseeAges Up to 21 years - NCT04903782Recruiting
Family whole-genome testing for children with newly diagnosed cancer
This study offers whole-genome testing (a way to read a person’s DNA) to families after a child is newly diagnosed with cancer. It aims to find inherited changes that may explain why cancer happened and guide future care or monitoring.
Newcastle, New South WalesAges Up to 21 years - NCT04905537Recruiting
Genetic screening for newborns after a serious pregnancy loss
This trial looks at doing early genetic testing in newborns/early life cases after a serious pregnancy loss, to learn whether genetics can help understand why it happened. If you have the right timing and sample availability, the results may help future “more precise” care planning and research.
Shanghai, Shanghai MunicipalityAges Up to 3 months - NCT04908696Recruiting
Treatment study for laryngeal and hypopharyngeal cancers
This trial tests treatment approaches for people with cancers of the voice box (larynx) or lower throat (hypopharynx). It may help by finding which treatment strategy works best for different tumor locations and cancer stages.
Shanghai, Shanghai MunicipalityAges 18–90
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,808 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.