Tocilizumab for acute chest syndrome in sickle cell
Treatments studied
Part of Blood & lymphatic, Genetic & congenital, Lungs & breathing clinical trials.
This trial studies tocilizumab (a medicine that calms inflammation) to treat acute chest syndrome in people with sickle cell disease. It may help improve symptoms and recovery by targeting key immune signals involved in this complication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 12 or older
- You have a confirmed diagnosis of sickle cell disease (Hb SS, Hb SC, Hb Sβ+, or Hb Sβ0)
- You are not pregnant and not breastfeeding
- You have not had gene therapy or a stem cell transplant in the past
- Your current blood counts are not too low (neutrophils ≥ 1000/mm³ and platelets ≥ 50,000/mm³)
- You have not had certain TB test results or active TB
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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