Clinical trials
Generalized Anxiety Disorder clinical trials
Below are recruiting generalized anxiety disorder clinical trials, each written for real people, not researchers. We’re tracking 128 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06243614RecruitingPhase 3
Testing buagafuran capsules for generalized anxiety disorder
This trial tests a new medication called buagafuran for people with generalized anxiety disorder (GAD). It aims to see if the drug can safely reduce anxiety symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06243640RecruitingPhase 3
New capsule for generalized anxiety disorder trial
This trial tests a new capsule called Buagafuran for adults with generalized anxiety disorder (GAD). It aims to see if the medication helps reduce anxiety without causing major side effects.
Beijing, Beijing MunicipalityAges 18–65 - NCT06506253Recruiting
Massage for generalized anxiety: brain imaging and response
This study tests if massage therapy can help people with generalized anxiety disorder (GAD) and uses brain scans to see how it works. You may join if you have GAD, are not on certain medications or are stable on them, and can lie face down or face up for an hour.
Salt Lake City, UtahAges 18–64 - NCT06770517Recruiting
Exposure therapy for anxiety in older adults
This study tests whether exposure therapy helps older adults with anxiety. It focuses on people 60 and older who have conditions like generalized anxiety, panic disorder, agoraphobia, or social anxiety.
Nederland, NijmegenAges 65 years+ - NCT06831708Recruiting
Comparing two types of talk therapy for generalized anxiety
This trial compares two short-term therapies—psychoanalytic and cognitive behavioral—for people with generalized anxiety disorder (GAD). It aims to see which approach works better over 12 weekly sessions.
IstanbulAges 18–65 - NCT07239609RecruitingPhase 1
ACT therapy for memory loss and their caregivers
This study tests if ACT, a type of talk therapy, helps people with mild memory loss and their care partners cope with difficult emotions. Both you and a family member or friend who helps you would participate.
Lubbock, TexasAges 18 years+ - NCT05962879Recruiting
Program for teens with early psychosis-like experiences
This trial tests a new mental health program for teenagers who are having at least one psychosis-like experience and may be at risk for serious mental illness. It may help by offering structured support for both teens and their parents.
Boston, MassachusettsAges 14–19 - NCT05863520Recruiting
Two school programs to help anxious autistic students
This study compares two school-based programs to reduce anxiety in autistic students ages 8–14. You may be able to help test which approach works better when delivered by trained school staff with caregiver involvement.
Aurora, ColoradoAges 7–15 - NCT07571226Recruiting
Urban Stress and Mental Health Monitoring Study
This study explores how city living and daily stress affect depression, anxiety, and alcohol use disorders by having you wear a monitoring wristband and use a smartphone app to track your physical responses. Researchers hope to better understand the link between environmental stress and mental health symptoms.
BeijingAges 18–60 - NCT06081348RecruitingPhase 2
Sertraline vs. placebo for anxiety in kids with developmental disorders
This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.
Calgary, AlbertaAges 8–17 - NCT05466851Recruiting
Study testing anxiety and depression biology and therapy markers
This study looks at “biopsychosocial markers” (biological, psychological, and social signs) in people with major depression and/or anxiety. It aims to understand what changes with treatment and how those changes connect to symptoms like anxiety and depression.
New York, New YorkAges 18–65 - NCT07538427Recruiting
Music Therapy for Health in Rural Elder Care
This study explores whether music can improve health and wellbeing in older adults living in rural care facilities. Researchers will work with residents to understand how music might help with mood, memory, and quality of life.
Flagstaff, ArizonaAges Any age - NCT07153250Recruiting
Online parent training for young child anxiety
This trial tests an online program that teaches parents how to help their young child (ages 2 to 7) manage anxiety. You would complete the program at home, and researchers want to see if it reduces your child's anxiety symptoms.
Boston, MassachusettsAges 18 years+ - NCT04214561Enrolling by invitation
Studies how sleep measures relate to teeth grinding
This study looks at sleep testing results to understand what relates to sleep bruxism, which is teeth grinding or clenching during sleep. It may help researchers better understand the causes and patterns behind this condition.
WroclawAges 18–70 - NCT06004115RecruitingPhase 4
Brain scanning study for depression and anxiety
This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.
Tulsa, OklahomaAges 18–65 - NCT06715852Recruiting
Moving on! Anxiety treatment in primary care
This study in Swedish primary care tests a tailored treatment program (including exercise) for people with anxiety disorders. It aims to see if this approach helps reduce anxiety better than usual care.
GothenburgAges 18–65 - NCT07167849Recruiting
Digital help while waiting for therapy
This trial tests a brief digital program for people waiting for outpatient therapy. It aims to provide support during the wait and see if it helps improve mental health symptoms.
BernAges 18 years+ - NCT07299916Enrolling by invitation
Brain stimulation and virtual reality for anxiety disorders
This trial tests if a combination of non-invasive brain stimulation (tDCS) and virtual reality meditation can reduce anxiety in people with Generalized Anxiety Disorder or related conditions. It aims to find a new, non-medication way to help manage symptoms.
Hong KongAges 16–70 - NCT05569018Recruiting
Spanish blended group therapy for anxiety and depression symptoms
This study tests whether a group therapy program delivered in both online and in-person formats can reduce emotional symptoms like anxiety and depression. If you qualify, you may be assigned to receive this structured group treatment during the study period.
Castellon, CastellónAges 18 years+ - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT07219992Recruiting
Parent-led treatment for teens with anxiety
This study tests a program that helps parents learn ways to support their teenager who has an anxiety disorder, like social anxiety or panic attacks. The goal is to see if this parent-based approach can reduce the teen's anxiety without the teen needing to attend therapy sessions.
New Haven, ConnecticutAges 14–17 - NCT05232032RecruitingPhase 2
Brain scan and medication study for avoiding versus approaching
This Phase 2 study looks at how a medication affects brain activity and real-life mood or anxiety behaviors. It includes people with major depression or several anxiety disorders and also healthy volunteers, using questionnaires, a smartphone, and brain imaging.
Belmont, MassachusettsAges 18–45 - NCT06297200Recruiting
Ultrasound treatment for complex back pain patients
This study tests a new, non-invasive ultrasound treatment for people with long-term back pain who also have opioid use disorder and anxiety. It aims to see if this gentle brain stimulation can reduce pain and improve quality of life.
Roanoke, VirginiaAges 18–65 - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85
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Common questions
- Are there clinical trials for generalized anxiety disorder?
- Yes. Clin2 currently lists 128 recruiting generalized anxiety disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a generalized anxiety disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a generalized anxiety disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.