Clinical trials
Genetic Predisposition clinical trials
Below are recruiting genetic predisposition clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04903782Recruiting
Family whole-genome testing for children with newly diagnosed cancer
This study offers whole-genome testing (a way to read a person’s DNA) to families after a child is newly diagnosed with cancer. It aims to find inherited changes that may explain why cancer happened and guide future care or monitoring.
Newcastle, New South WalesAges Up to 21 years - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74 - NCT05661305Recruiting
Egyptian healthy adults for heart and MRI study
This trial studies how healthy hearts work in Egyptian adults who do not have known heart problems. It may help researchers understand heart health and risk factors, using an MRI scan.
AswānAges 18 years+ - NCT06020625Recruiting
Genetic testing for advanced cancers
This trial investigates genetic testing (mutational profiling) in people with various advanced cancers. It aims to understand how these tests can guide more personalized treatment decisions.
RomeAges 18 years+ - NCT05661318Recruiting
Study of heart health in Ballana adults
This study is looking at heart health in adults living in Ballana. Your involvement could help researchers understand local heart risks and needs in the community.
AswānAges 18 years+ - NCT05772559Recruiting
Study of AML genes and drug response in young patients
This trial looks at how childhood, teen, and young adult acute myeloid leukemia (AML) changes at the genetic level and how cells respond to multiple drugs. It may help doctors understand which treatments work best and how leukemia interacts with supportive cells in the bone marrow.
AmiensAges Up to 25 years - NCT06446271Recruiting
Biomarkers in Scottish Cardiomyopathy Registry
This study looks for signs of heart muscle disease (cardiomyopathy) in people who have certain genetic changes. It aims to find better ways to monitor and treat the condition.
GlasgowAges 10 years+ - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT04521790Recruiting
Biopsy-guided treatment for suspected inflammation of the heart
This study looks at people 18 and older with suspected myocarditis (inflammation of the heart). It uses an inner-heart biopsy and tailored treatment based on the likely cause to improve diagnosis and care, especially for people with different heart rhythm or non-rhythm symptoms.
Milan, MilanoAges 18 years+ - NCT07756320Enrolling by invitation
Mayo clinic trial for rapid enrollment and targeted study growth
This trial aims to improve how Mayo Clinic enrolls patients in research studies. If you join, you'll help researchers learn how to make trials run faster and more smoothly, which could benefit future patients.
Rochester, MinnesotaAges 18 years+ - NCT06591260Recruiting
Heart biopsy and treatment for kids with heart inflammation
This study looks at using heart biopsies to find the cause of heart inflammation (myocarditis) in children and then tailoring treatment to that cause. It aims to improve care for children with or without irregular heartbeats.
Milan, MilanoAges birth–17 years - NCT07728175RecruitingPhase 1
Sirolimus for Alzheimer's risk in women with ApoE4 gene
This study tests whether sirolimus, a medication that may help the body clear damaged cells, can lower Alzheimer's risk in women with the ApoE4 gene variant. It is an early-stage trial that looks at safety and how the drug affects certain blood markers.
Columbia, MissouriAges 45–65 - NCT06680791Recruiting
Endometrial cancer study on recurrence prevention and lifestyle
This study looks at how your cancer type and daily habits might help prevent endometrial cancer from coming back. It only requires that you've had endometrial cancer and a hysterectomy.
PragueAges Any age - NCT05317234Recruiting
Genetic testing study for children with cerebral palsy
This study looks for genetic reasons that may contribute to cerebral palsy. It may help families understand potential causes, especially when a specific genetic change is found.
BronAges 2–15 - NCT07332598Enrolling by invitation
Mayo Clinic precure study for prevention of blood cancers
This study aims to learn how to prevent blood cancers. You will provide samples over time so researchers can look for early signs of cancer.
Rochester, MinnesotaAges 18 years+ - NCT07272200Recruiting
Genes and alcohol in liver cancer: a study
This study looks at how your genes and alcohol use together affect the risk of liver cancer. It may help find ways to prevent cancer in people with fatty liver disease or moderate alcohol intake.
Milan, MilanoAges 45–75 - NCT07264790RecruitingPhase 1
Minoxidil for Better Blood Flow in Breast Reconstruction
This trial tests whether applying minoxidil (a hair growth medication) to breast tissue during surgery can improve blood flow to the reconstructed breast. It is for women who are having both breasts removed to prevent cancer and have reconstruction on the same day.
Durham, North CarolinaAges 18 years+ - NCT06993142Recruiting
Slowing Parkinson's Early With Exercise
This trial tests whether a specific exercise program can slow the early stages of Parkinson's disease in people who have a genetic risk (LRRK2 or GBA variants). You will use a smartphone app to guide your exercise from home.
Rochester, New YorkAges 50 years+ - NCT06962059Recruiting
Healthy volunteers with ovaries needed for study
This study is looking for healthy volunteers who still have their ovaries and have not had cancer or certain genetic mutations. Researchers want to learn more about ovarian health.
Philadelphia, PennsylvaniaAges 30–50 - NCT06792721Recruiting
Measuring mutation levels in siblings with BRCA risk
This study looks at how genetic mutations (changes in DNA) are measured in the blood of sisters. One sister has a BRCA1 or BRCA2 gene mutation that raises cancer risk, and the other does not. The goal is to understand mutation differences between them.
Caen, FranceAges 30–50 - NCT05929976Recruiting
Study of gut and blood chemistry in children with new leukemia
This study looks at the gut microbiome (tiny organisms in the gut) and metabolome (small chemicals in the body) in children and teens with newly diagnosed ALL. It may help researchers understand what is happening in the body early in treatment and could guide future, more personalized care.
New York, New YorkAges 3–18 - NCT06659614Recruiting
Prostate tissue collection for future cancer research
This study collects prostate tissue samples from men who are either at higher risk due to a gene change or are getting a biopsy or prostate surgery for routine care. The samples are stored in a biobank for future research on prostate cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06554288RecruitingPhase 1
Trihexyphenidyl for dystonia in cerebral palsy
This study tests how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy, a condition that causes muscle spasms. Researchers want to learn if a child’s genes affect how the medicine works and how the body processes it.
Kansas City, MissouriAges 5–17 - NCT06470685Enrolling by invitation
Preventive prostate removal for prostate cancer risk
This study tests whether removing the prostate before cancer develops can help people at higher risk, such as those with certain gene changes (like BRCA2), a strong family history, or Black African/Caribbean ancestry. It also includes people who have already had their prostate removed for cancer treatment.
LondonAges 18 years+
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Common questions
- Are there clinical trials for genetic predisposition?
- Yes. Clin2 currently lists 70 recruiting genetic predisposition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetic predisposition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetic predisposition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.