Clinical trials
Genetics clinical trials
Below are recruiting genetics clinical trials, each written for real people, not researchers. We’re tracking 704 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07193134RecruitingPhase 1/Phase 2
Gene-modified skin graft for RDEB
This trial tests a new skin graft made with your own cells that have been genetically modified to produce a missing protein (collagen 7). It's for people with RDEB, a severe blistering condition, and aims to see if the graft can heal wounds safely.
Toronto, OntarioAges 7 years+ - NCT07206095Recruiting
Better diagnosis for inherited red blood cell diseases
This trial aims to improve how doctors diagnose rare inherited anemias, including sickle cell disease and other conditions that destroy red blood cells. It may help if you have a confirmed or suspected diagnosis but need more clarity through advanced testing.
Barcelona, BarcelonaAges Any age - NCT07207564Recruiting
Improving breast cancer risk with pathology, radiology, and genetics
This study looks at tissue, imaging, and genetic information from women who had a non-cancerous breast biopsy to better understand breast cancer risk. It may help improve how we predict and prevent breast cancer in the future.
Jacksonville, FloridaAges 18–100 - NCT07215416RecruitingPhase 1/Phase 2
Gene therapy for ataxia-telangiectasia with specific ATM mutation
This trial tests a new genetic medicine designed for people with A-T who have a specific ATM gene change. It aims to see if the treatment is safe and if it can improve symptoms.
Boston, MassachusettsAges birth–17 years - NCT07217522Recruiting
Genetics of pulmonary hypertension study
This study looks at the genes that may be linked to pulmonary hypertension. By providing a saliva sample and filling out a health survey from home, you can help researchers learn more about this condition.
Piscataway, New JerseyAges 18 years+ - NCT07217535Recruiting
Studying the genetics of kidney disease
This study collects DNA and health information from people in the U.S. to better understand how genes may affect kidney disease. Your participation could help researchers find new ways to prevent or treat kidney problems.
Piscataway, New JerseyAges 18 years+ - NCT07227571RecruitingPhase 1
CAR T cells for advanced osteosarcoma
This trial tests whether specially engineered immune cells (called CAR T cells) can attack and kill osteosarcoma tumors that have not responded to standard treatments. It may be an option for children and adults whose cancer has returned or is not controlled by chemotherapy.
Seattle, WashingtonAges 1–75 - NCT07233915Recruiting
Genetic Study of Berry-Shaped Brain Aneurysms
This study looks at the genetic makeup of people with berry-shaped brain aneurysms. It may help researchers understand why some aneurysms rupture and others don't.
Milan, MIAges 18–80 - NCT03412877RecruitingPhase 2
Personalized immune-cell therapy for advanced metastatic cancers
This trial tests a personalized cell therapy made from your own immune cells, changed to recognize “neoantigens” on cancer cells. It’s designed for people with metastatic (advanced spread) solid cancers or certain other cancers who have tried standard treatments but cancer is still growing.
Bethesda, MarylandAges 18–72 - NCT07270679Recruiting
Genetic markers for ovarian damage after chemo
This study is looking for genetic markers that may help predict how chemotherapy affects the ovaries. It's for women who had breast cancer or lymphoma, froze their ovarian tissue before treatment, and finished that treatment at least 6 months ago.
Bologna, BolognaAges 18–38 - NCT07278115Recruiting
Gastric bypass with or without nerve-cutting for diabetes
This study compares two types of surgery for people with type 2 diabetes who also have obesity: gastric bypass alone versus gastric bypass plus a procedure called truncal vagotomy (cutting a nerve to the stomach). It aims to see which approach leads to better diabetes remission.
Athens, AtticaAges 18–68 - NCT07307664Recruiting
Increasing genetic testing for cancer patients
This trial aims to increase the use of genetic testing (germline testing) among cancer patients by working with healthcare providers like oncologists and nurses. If you are an oncology care team member treating adults with breast, pancreatic, or colorectal cancer, this study may be for you.
Los Angeles, CaliforniaAges Any age - NCT07312240Recruiting
Biomarkers in ALS: A long-term study
This study is looking for people with ALS to help doctors understand how certain biological markers (biomarkers) change over time. It involves a lumbar puncture (spinal tap) to collect fluid from your spine and regular check-ups.
Milan, LombardyAges 18 years+ - NCT07329257Recruiting
Project PENGUIN: Study of rare brain development disorders
This study looks at rare and ultra-rare conditions that affect brain development. It aims to learn more about what causes these conditions. You may join if you or your child have a diagnosed or suspected neurogenetic disorder.
Columbia, MissouriAges Up to 99 years - NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years - NCT07358013Recruiting
Endothelial cells in von Willebrand disease and related conditions
This study looks at special cells from blood vessels (endothelial colony-forming cells) in people with von Willebrand disease (a bleeding disorder) or a related acquired condition. The goal is to better understand these conditions using blood donations.
MilanAges 16 years+ - NCT07361471Recruiting
Ovarian cancer genetics: comparing platinum response groups
This study looks at genetic and other factors that may explain why some people with ovarian cancer respond well to platinum-based chemotherapy for many years, while others do not respond at all. The goal is to better understand these differences to improve future treatments.
Clermont-Ferrand, PUY DE DOMEAges 18 years+ - NCT07370792Recruiting
Genetic mapping for multiple birth defects or intellectual disability
This study uses a new genetic technique to find hidden causes in people with multiple birth defects or intellectual disability who had standard genetic tests come back normal. It might help identify a genetic reason when other tests did not.
Clermont-FerrandAges Any age - NCT07378423Recruiting
Survey on signs of cancer at birth
This trial asks newly diagnosed children and young adults with certain types of cancer to fill out a questionnaire about signs of cancer present at birth. The answers may help improve early detection of childhood cancer.
BernAges Up to 21 years - NCT07385287RecruitingPhase 2
Malaria vaccine trial for healthy adults in Burkina Faso
This study tests a new malaria vaccine called PfSPZ-LARC2 in healthy adults living in Burkina Faso. If you qualify, the vaccine is given to see if it can protect you from malaria.
OuagadougouAges 18–50 - NCT07389720Recruiting
Sensorimotor pathways in children with autism
This study looks at how the brain controls movement and senses in children with autism compared to typically developing children. It also includes infants with a family history of autism and parents of all participants.
Bosisio Parini, LeccoAges 1 year+ - NCT07391293Recruiting
Genetic aortic diseases and heart risks observational study
This study looks at people with genetic aortic diseases to understand risk factors for heart complications. By joining, you help researchers learn more about these conditions and how to better manage them.
MilanAges 14–60 - NCT00556530Recruiting
Study genes and severity in 22q11.2 deletion
This study looks at how genetic differences affect how severe 22q11.2 deletion syndrome is for different people. It may help researchers understand what drives symptom severity and guide future care.
New York, New YorkAges Any age - NCT00682695Recruiting
Study genetic and environmental risks for brain bleeding stroke
This study looks at how genes and life factors may contribute to a type of stroke caused by bleeding in the brain. You may be eligible if you’ve had a spontaneous (not caused by injury or infection) brain bleed and can complete consent, interviews, blood pressure checks, and a DNA sample.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for genetics?
- Yes. Clin2 currently lists 704 recruiting genetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.