Clinical trials
Genetics clinical trials
Below are recruiting genetics clinical trials, each written for real people, not researchers. We’re tracking 696 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05133245Enrolling by invitation
Study of genes in people with PHACE syndrome
This study looks at genetic (DNA) differences in people who have PHACE syndrome. It also includes an eye exam, and results may help doctors better understand the condition.
Nashville, TennesseeAges Any age - NCT05020574RecruitingPhase 2
Study how the microbiome may affect breast implant infections
This Phase 2 study looks at whether changes in the body’s “microbiome” (the normal germs in and on the body) are linked to infections after breast surgery with implants. It may help doctors better predict and prevent implant infections in people undergoing mastectomy with immediate implant placement.
San Francisco, CaliforniaAges 18 years+ - NCT05010031RecruitingPhase 2
Lower-dose radiation for metastatic cancer with an ATM mutation
This trial tests whether giving a lower dose of radiation can help control metastatic tumors that carry a specific genetic change in the ATM gene. It may reduce side effects by using less radiation, while still aiming to keep the tumor under control.
Basking Ridge, New JerseyAges 18 years+ - NCT04970056Recruiting
Pancreatic cancer risk and early-detection registry study
This study builds a database of people at higher risk for pancreatic cancer (or certain early warning findings) to help find better ways to detect the disease early. You may be asked to complete health questionnaires and possibly donate a blood/saliva/swab sample.
Phoenix, ArizonaAges 18–90 - NCT04995224Recruiting
Study what causes long-term pain in new Crohn’s or colitis
This study looks at why some people develop long-term pain after being newly diagnosed with ulcerative colitis or Crohn’s disease. It may help researchers understand the pain process and improve future treatments.
LondonAges 18 years+ - NCT04888936Recruiting
Study families with genetic RAS syndromes, including adults and children
This study looks at people with certain inherited genetic conditions called RASopathies and their family members. It helps researchers understand these conditions and how genetic changes run in families, which may improve future care.
Bethesda, MarylandAges 1 month–99 years - NCT04924075RecruitingPhase 2
Belzutifan for cancers linked to VHL or HIF-2α changes
This Phase 2 study tests belzutifan (MK-6482) to treat certain advanced cancers caused by specific gene or disease changes, including VHL-related tumors and HIF-2α related tumors. It may help shrink tumors or slow their growth in people whose cancer matches these genetic or disease patterns.
Los Angeles, CaliforniaAges 12 years+ - NCT04873492Recruiting
Study how genes and blood signals relate to MS outcomes
This study looks at genetic information and blood test signals to understand why some people with early MS develop a worse outcome. It may help doctors predict who is at higher risk and better understand disease mechanisms.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT04906863Recruiting
Genetic study for early dementia in adults and families
This trial studies genes to better understand why some people develop dementia and memory problems earlier in life. It may help researchers find clearer causes and improve future testing and treatments for families affected by dementia.
New York, New YorkAges 35 years+ - NCT02124499Recruiting
Study links genes to complications after scheduled surgery
This study looks at how certain genetic differences may affect the risk of complications and recovery outcomes after surgery. It may help doctors understand who is more likely to have problems around the time of an operation.
BernAges 18 years+ - NCT03489499Recruiting
Genetic testing study of pain after planned surgery
This study looks at whether genetic differences can help predict how much pain you may have after an elective (planned) operation. If you qualify, you may be asked to give consent and share information so researchers can compare pain experiences across people.
BernAges 18 years+ - NCT04772963Recruiting
Genetics study for brain blood vessel malformations
This study looks at genetic (inherited DNA) factors in people with certain abnormal blood vessel connections in the brain or spinal cord. It may help researchers understand why these malformations happen and how they might behave over time.
ParisAges Any age - NCT04848090Enrolling by invitation
Genetic testing for newborns in the hospital intensive care unit
This study uses whole-genome sequencing (a DNA test that looks across the genome) for newborns in the intensive care unit when doctors suspect a genetic condition. It aims to help identify possible genetic causes of illness and improve understanding for families and clinicians.
Pittsburgh, PennsylvaniaAges Up to 1 year - NCT04824040Enrolling by invitation
Study of immune, muscle, and genetic features in LGMD 2B
This study looks at immune function, muscle appearance, and genetic information in people with limb-girdle muscular dystrophy type 2B. It may help researchers understand the condition better, which can support future treatments.
MoscowAges 18–85 - NCT04831164Recruiting
Study of shoulder rotator cuff tears and genetics
This study looks at how genes and risk factors relate to rotator cuff tears by comparing people with and without these tears. It may help researchers understand why tears happen and who is most at risk.
Iowa City, IowaAges 40–85 - NCT01858285Recruiting
Genetics study for children with epilepsy
This study looks for genetic (inherited DNA) causes of epilepsy in children. It may help your family better understand what could be driving seizures, even if the cause isn’t known yet.
Boston, MassachusettsAges Any age - NCT04698291Recruiting
Study how genetic differences affect calming immune signals
This study looks at how genetic changes may affect special “calming” immune molecules that help the body resolve inflammation. You may be invited if you already joined the Genes & Health project and had your genome analyzed, and you meet safety and health criteria.
LondonAges 18 years+ - NCT04703179Enrolling by invitation
Rare disease and undiagnosed case research blood and tissue biobank
This study collects and stores samples and related medical information for people with rare diseases or suspected genetic conditions. It may help researchers better understand these conditions and develop future testing and treatments.
Scottsdale, ArizonaAges Any age - NCT04731857Recruiting
Genetic testing results study for rare diseases
This study looks at how well different genetic tests (whole exome/genome sequencing and standard genetic tests) work for diagnosing rare genetic diseases and inherited cancer conditions. It may help confirm which testing approach provides the clearest results for families.
TübingenAges Any age - NCT04612296Recruiting
Heart Hive study for cardiomyopathy and family history
This observational study looks at people with cardiomyopathy or myocarditis, and people with a close family history of these conditions. It aims to better understand the condition and what factors may be involved.
LondonAges 18 years+ - NCT04639622Recruiting
Study for inherited frontotemporal dementia gene risks
This study recruits adults who come from families with certain known gene changes linked to frontotemporal dementia. It aims to learn more about these inherited forms of dementia using brain scans and research blood testing, which will not provide personal results.
LilleAges 18 years+ - NCT04681781Enrolling by invitation
Remote study of SLC13A5 deficiency history
This study follows people with SLC13A5 deficiency to better understand how the condition changes over time, using surveys and clinical check-ins done remotely. If you (or your child) have this genetic condition, it may help researchers learn what symptoms to expect and how to track them.
Palo Alto, CaliforniaAges Any age - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04661072Recruiting
Study genes and cancer risk in uterine birth differences
This study looks at how genetic factors and environment may relate to cancer risk in people with uterine birth differences. It also aims to improve clinical care by learning what patterns show up in real-world patients.
New Haven, ConnecticutAges 13 years+
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Common questions
- Are there clinical trials for genetics?
- Yes. Clin2 currently lists 696 recruiting genetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.