Clinical trials
Genetics clinical trials
Below are recruiting genetics clinical trials, each written for real people, not researchers. We’re tracking 704 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06610695Enrolling by invitation
Bile acid PET/CT scan for genetic liver disorders
This study uses a special PET/CT scan with a tracer called 11C-Csar, which is similar to bile acid, to see how well your liver handles bile. It is for healthy people and those with genetic liver diseases that cause cholestasis (slowed bile flow). The goal is to improve diagnosis and understanding of these conditions.
AarhusAges 18 years+ - NCT06584994Enrolling by invitation
Genetics and cancer risk in families
This study looks at how genes passed down in families might increase the chance of getting cancer. It collects samples from children with cancer and their family members to better understand cancer risks.
CambridgeAges Any age - NCT06450964Enrolling by invitation
Studying Mitochondrial Disease to Improve Genetic Counseling
This study aims to learn more about mitochondrial DNA diseases by building a group of people with these conditions. The information gathered may help doctors give better genetic counseling to families.
Hefei, AnhuiAges Any age - NCT03544983Enrolling by invitation
Genetic education program for BRCA family members
This trial offers education about BRCA1 and BRCA2 gene mutations to help families understand testing, cancer risk, and next steps. It may be helpful if you are a family member of someone who recently learned they have a BRCA mutation.
Washington D.C., District of ColumbiaAges 21–75 - NCT03385876Enrolling by invitation
Rapid whole genome sequencing for children with suspected genetic illness
This study quickly reads a child’s DNA using whole genome sequencing to look for genetic causes of symptoms. It may help families and doctors better understand an underlying genetic condition and guide medical care.
San Diego, CaliforniaAges Any age - NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years - NCT06595940Recruiting
Genetic study of unusual disease in non-US populations
This study looks for genetic causes of rare or unusual disease patterns in people living outside the United States. If you or a family member has a condition that seems to run in the family, started very early, or has an unusual form, you may be asked to provide a DNA sample and medical history.
MokaAges 2–100 - NCT06659341RecruitingPhase 1
Study of BAY3498264 with Sotorasib for KRAS G12C Cancers
This trial tests a new drug (BAY3498264) combined with sotorasib, a targeted therapy, for people with advanced cancers that have a specific genetic change called KRAS G12C. It's for those who have already tried other treatments and need new options.
Albury, New South WalesAges 18 years+ - NCT06948110Recruiting
Searching for genes linked to autoimmune diseases
This study looks for genes that may be linked to autoimmune diseases by comparing the DNA of people with these conditions to healthy family members or volunteers. If you have an autoimmune disease or are a healthy person interested in helping research, this study may help scientists understand why these diseases run in families.
Bethesda, MarylandAges 18–115 - NCT07587242RecruitingPhase 3
Testing a New Therapy for DMD with Exon 44 Mutations
This study tests whether a new medicine called AOC 1044 (delpacibart zotadirsen) can help boys with Duchenne muscular dystrophy (DMD) who have a specific genetic mutation. The medicine works by helping the body skip a damaged part of the gene to make a functional protein.
LeuvenAges 7–16 - NCT06494540Recruiting
TDC treatment for advanced non-squamous lung cancer
This study is looking at how well a new treatment called TDC (which includes durvalumab and chemotherapy) works for people with a certain type of advanced lung cancer that has spread and has specific genetic features. It aims to see if this treatment is effective and safe in the real world, and it might be an option if you are starting this therapy anyway.
Bad HomburgAges 18–120 - NCT07780513Recruiting
Genetics of muscle insulin resistance study
This study looks at how genes affect the way muscles use sugar, which can help understand insulin resistance. Participants will have tests and procedures, including a glucose drink test and a muscle biopsy, to see how their bodies handle sugar.
San Antonio, TexasAges 18–75 - NCT07174336RecruitingPhase 3
Testing Tersolisib with other treatments for advanced breast cancer
This trial tests a new study drug called Tersolisib combined with other anti-cancer treatments for people with advanced breast cancer that has a specific gene change (PIK3CA). The goal is to see if the combination can help shrink or slow the cancer.
Anchorage, AlaskaAges 18 years+ - NCT06576713Recruiting
Genome and RNA sequencing for genetic diagnosis of early Parkinsonism
This study uses advanced genetic testing (genome and RNA sequencing) to find the genetic causes of Parkinsonism that starts before age 40 or runs in families. If you join, you will provide a blood sample and a small skin biopsy to help researchers understand your condition better.
Strasbourg, Grand EstAges 18 years+ - NCT06058377RecruitingPhase 3
Adding immunotherapy to chemo for stage II-III breast cancer
This trial tests whether adding the immunotherapy drug durvalumab to standard chemotherapy works better than chemo alone for people with hormone receptor positive, HER2 negative breast cancer that is stage II or III and has a high-risk genetic score (MammaPrint High Risk 2).
Birmingham, AlabamaAges 18 years+ - NCT07221669RecruitingPhase 3
Pre-symptomatic salanersen study for babies with SMA
This trial tests if the drug salanersen can help movement and is safe when given to babies diagnosed with spinal muscular atrophy before they show symptoms. It's for very young infants with specific genetic types of SMA.
Chicago, IllinoisAges birth–1 month - NCT07772570Recruiting
Studying blood markers in coronary artery disease
This study collects blood samples and images from patients with heart muscle damage or those undergoing coronary angiography. The goal is to find new biomarkers that could improve diagnosis and treatment of coronary artery disease.
OxfordAges 18–90 - NCT05361720RecruitingPhase 2
Genetic test to match treatment for advanced kidney cancer
This study looks at genetic (RNA) testing of kidney cancer tissue to help choose the best drug treatment. It may help guide therapy for people with advanced or metastatic clear cell kidney cancer who are starting treatment for the first time.
Duarte, CaliforniaAges 18 years+ - NCT06064890RecruitingPhase 1/Phase 2
Gene therapy trial for genetic frontotemporal dementia
This trial tests a new gene therapy called AVB-101 for people with a specific genetic cause of frontotemporal dementia (FTD). The therapy is given as a one-time injection into the brain to potentially slow or stop the disease.
Columbus, OhioAges 30–75 - NCT07544992RecruitingPhase 1
CAR T Cells for Recurrent High-Grade Brain Tumors
This trial tests genetically engineered immune cells (CAR T cells) injected directly into the brain to treat recurring or worsening high-grade gliomas. The cells are designed to recognize and attack tumor cells that have specific markers (EGFR and IL13Rα2).
Duarte, CaliforniaAges 18 years+ - NCT06581146Recruiting
Liver health study for boys with XLMTM
This study looks at how the liver works in boys with a serious muscle condition called XLMTM. It checks whether their liver is healthy, which may help doctors better understand the condition and guide future treatments.
Santa Monica, CaliforniaAges Up to 17 years - NCT07469657Recruiting
Cost-effectiveness of a non-invasive prenatal test for genetic disorders
This study is testing a non-invasive prenatal blood test (NIPD) that can check for certain serious genetic disorders in your baby, instead of using more invasive methods like amniocentesis. If you are at risk of passing on a severe genetic condition, this test may help you get answers safely.
Paris, Île-de-France RegionAges 18 years+ - NCT07756320Enrolling by invitation
Mayo clinic trial for rapid enrollment and targeted study growth
This trial aims to improve how Mayo Clinic enrolls patients in research studies. If you join, you'll help researchers learn how to make trials run faster and more smoothly, which could benefit future patients.
Rochester, MinnesotaAges 18 years+ - NCT06775496Recruiting
Study of life-threatening infections to find genetic causes
This trial studies people who have had a life-threatening infection to look for genetic reasons why some infections are so severe. If you or a child had a serious infection—like severe flu, meningitis, or a deep abscess—that could not be explained by a weak immune system from other causes, this study may help find answers.
Bologna, BolognaAges Any age
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Common questions
- Are there clinical trials for genetics?
- Yes. Clin2 currently lists 704 recruiting genetics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genetics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genetics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.