Clinical trials
Genomics clinical trials
Below are recruiting genomics clinical trials, each written for real people, not researchers. We’re tracking 277 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04706663Recruiting
Genomics-guided treatment for people with prostate cancer
This trial uses genetic test results from your prostate cancer to guide treatment choices. It may help find therapies that better match the specific gene changes in your cancer.
La Jolla, CaliforniaAges 18–120 - NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT04812366RecruitingPhase 2
Genetic test-guided treatment before prostate surgery
This trial tests different drugs before prostate surgery based on a person's genetic profile. It aims to find better treatments for high-risk prostate cancer that hasn't spread yet.
Sacramento, CaliforniaAges 18 years+ - NCT06772623RecruitingPhase 1/Phase 2
Study of telisotuzumab adizutecan plus immunotherapy for advanced lung cancer
This trial tests a new combination treatment for people with advanced non-squamous non-small cell lung cancer who haven't received prior therapy for advanced disease and don't have specific gene changes. The treatment includes an antibody-drug conjugate (telisotuzumab adizutecan) plus an immunotherapy drug (PD-1 checkpoint inhibitor) to see if it helps shrink tumors and improve outcomes.
Phoenix, ArizonaAges 18 years+ - NCT07106632RecruitingPhase 3
Genomic test to guide chemotherapy in young women with breast cancer
This trial uses a genomic test called Prosigna to help decide whether young women with hormone-sensitive breast cancer need chemotherapy after surgery. It aims to avoid unnecessary chemotherapy in those who can safely skip it.
BrusselsAges 35–45 - NCT00359684Recruiting
Cysteamine treatment for cystinosis
This trial looks at the use of cysteamine to treat cystinosis, a rare inherited condition. It may help lower harmful cystine buildup in the body and improve outcomes, especially early in life.
Bethesda, MarylandAges 1 week–115 years - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT04419870Recruiting
Studying infections and immune responses in mitochondrial disease
This study looks at what happens in the body when someone with mitochondrial disease gets a sudden (acute) infection, and how the immune system and metabolism respond. Results may help doctors better recognize and manage infections in people with mitochondrial disease.
Bethesda, MarylandAges 2 months–115 years - NCT02890342Recruiting
Studying Propionic Acidemia, gut bacteria, and body chemistry over time
This study follows people with propionic acidemia to better understand how the body, diet, gut bacteria, and blood chemistry change over time. It may help researchers learn more about the condition and how pregnancy, transplant, and daily life affect health.
Bethesda, MarylandAges 1 month–100 years - NCT07250204Recruiting
Testing nipple discharge to tell benign from malignant breast disease
This study uses a blood test and a sample of nipple discharge to see if it can help doctors tell the difference between non-cancerous and cancerous conditions in the breast ducts. It aims to find a better way to diagnose intraductal disease without needing surgery right away.
Wuhan, HubeiAges 18 years+ - NCT07405190RecruitingPhase 2
Ivonescimab with or without chemo for advanced NSCLC
This study tests a new drug, ivonescimab, alone or with chemotherapy (carboplatin and pemetrexed), for people with advanced lung cancer that has specific gene changes and has already been treated with targeted therapy. It aims to see if the drug can shrink tumors or slow the cancer's growth.
Boston, MassachusettsAges 18 years+ - NCT03089554RecruitingPhase 2
Genetic tumor testing to guide targeted cancer treatments
This trial studies how doing genetic (DNA) testing on your cancer helps doctors choose targeted treatments, and how those treatments affect outcomes. It is for adults whose cancer has not responded to the first standard treatment or who do not have curative options.
Lexington, KentuckyAges 18 years+ - NCT03458962Recruiting
Whole genome testing for children with an unknown genetic cause
This study uses whole genome sequencing (a complete DNA readout) to look for a genetic reason why a child’s medical symptoms are happening. It’s mainly for children who have had at least one test but still do not have a clear diagnosis, and it may help doctors find the right diagnosis or next steps.
Miami, FloridaAges Up to 21 years - NCT03740503Recruiting
Study genes in people who respond unusually to treatment
This study looks at stored tumor samples to understand why some people respond much better or much worse than expected. The goal is to learn what the tumor’s genes might be telling doctors about response to treatment.
Toronto, OntarioAges 18 years+ - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT07703670Recruiting
MicroRNA markers in first episode schizophrenia
This study looks at tiny molecules called microRNAs in the blood of people having their first episode of schizophrenia. It aims to find markers that could help guide treatment choices.
Glen Oaks, New YorkAges 15–40 - NCT04167748Recruiting
Genetic testing for embryos in IVF for women 35–40
This study looks at using embryo genetic testing before pregnancy in IVF for women aged 35 to 40. It may help by identifying which embryos are more likely to lead to a healthy pregnancy, though you would still be screened to confirm you fit the criteria.
Margate, FloridaAges 35–40 - NCT04187729Recruiting
Precision Genomics Biobank for People Seen in Clinic
This study builds a large DNA and health information “biobank” from adults who visit Intermountain Health. It may help researchers understand how genes relate to health and disease by comparing “healthy” people with people who have medical conditions.
Murray, UtahAges 18 years+ - NCT04315233RecruitingPhase 1
Testing two drugs for hard-to-treat triple-negative breast and ovarian cancer
This Phase 1 trial tests ribociclib plus belinostat in people with metastatic triple-negative breast cancer or recurrent ovarian cancer. It also looks at your tumor’s genetics (from a fresh biopsy) to see who might respond better.
Salt Lake City, UtahAges 18 years+ - NCT04340817Recruiting
Study of fatty liver in Nordic countries
This study looks at people with non-alcoholic fatty liver disease (fat buildup in the liver without heavy alcohol use). It may also include healthy volunteers for comparison, helping researchers understand the condition better.
Hvidovre, Capital Region DenmarkAges 18 years+ - NCT04341181RecruitingPhase 2
Targeted cancer treatment chosen by tumor genetic test results
This Phase 2 trial matches people with advanced cancer to a targeted treatment based on a genetic (DNA) or protein (IHC) test from their tumor. It’s for cancers that are no longer responding to standard treatment or where no standard option is available.
Aalborg, AalborgAges 18 years+ - NCT04344496Recruiting
Collecting breast cancer tissue to predict recurrence risk
This study builds a “genome atlas” to better predict the chance that breast cancer will come back. It asks participants to share medical information and provide blood and tumor tissue samples, including samples kept in paraffin.
TaipeiAges 20 years+ - NCT04416178Recruiting
Survey and interviews for families affected by sickle cell disease
This study collects feedback through surveys, interviews, and focus groups from people affected by sickle cell disease. Your input helps the research team improve how genomic and gene-therapy information and needs are understood for patients and caregivers.
Memphis, TennesseeAges 13 years+ - NCT04477863Recruiting
Follow-up study for people who had genetic testing in embryos
This trial follows up with people who chose to participate in research when getting preimplantation genetic testing (testing genes in embryos). It may help researchers understand outcomes and improve future genetic testing and counseling.
North Brunswick, New JerseyAges Any age
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Common questions
- Are there clinical trials for genomics?
- Yes. Clin2 currently lists 277 recruiting genomics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genomics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genomics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.