Clinical trials
Glaucoma clinical trials
Below are recruiting glaucoma clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04354545Recruiting
Testing treatments for eye discomfort in glaucoma
This trial studies how to treat eye surface discomfort in people who have glaucoma and are already using multiple eye drops. It may help reduce symptoms like irritation while keeping glaucoma treatment on track.
Fountain Valley, CaliforniaAges Any age - NCT04396002Recruiting
Study of life movement and vision loss in older adults
This study looks at whether how far and how much you move around each day is linked to glaucoma and vision field loss in older adults. It may help researchers understand what affects vision changes over time.
Birmingham, AlabamaAges 18–100 - NCT04416724Recruiting
Surgery versus laser for early pseudoexfoliation glaucoma
This trial compares cataract surgery (phacoemulsification) versus a laser treatment (SLT) as the first treatment for pseudoexfoliation glaucoma. It aims to find which approach lowers eye pressure and helps prevent progression for people with early disease and cataracts.
Halifax, Nova ScotiaAges 50 years+ - NCT04519619Recruiting
Safety study of aflibercept eye injections in Japanese glaucoma patients
This trial checks how safe aflibercept (eye injection) is for Japanese people with neovascular glaucoma. You may be able to join if you already received aflibercept treatment under the approved Japanese instructions and have the correct diagnosis.
Multiple LocationsAges Any age - NCT04635020Recruiting
iStent versus laser for exfoliation glaucoma with cataract
This trial compares two treatment options for people with exfoliation glaucoma who also have cataracts: a tiny implant placed during cataract surgery (iStent) versus laser treatment. It aims to see which approach better controls eye pressure over 12 months and improves outcomes.
HelsinkiAges 50–100 - NCT04651530Recruiting
Endoscopic laser treatment for normal-pressure glaucoma
This study tests an endoscopic laser procedure to lower eye pressure and slow damage in people with normal-tension glaucoma. It may help protect the optic nerve, especially if your glaucoma is stable on drops and you also have a cataract.
HelsinkiAges 55–100 - NCT07425535RecruitingEarly Phase 1
Optic nerve strain study for people without glaucoma
This study looks at how the optic nerve (the part of your eye that sends images to your brain) strains or bends in people who do not have glaucoma. It uses advanced eye imaging and home pressure checks to understand the nerve's health.
Baltimore, MarylandAges 30–90 - NCT05039684Recruiting
Testing eye-surface inflammation in glaucoma or high eye pressure
This study measures inflammation markers on the eye surface in people with primary open-angle glaucoma or ocular hypertension who use certain glaucoma drops. The results may help doctors understand how these drops affect the eye and inflammation.
ValladolidAges 18–99 - NCT05206877RecruitingPhase 1
Topical insulin eyedrops for glaucoma-related eye nerve damage
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
Palo Alto, CaliforniaAges 18 years+ - NCT05275738Recruiting
Nicotinamide treatment for glaucoma progression
This trial studies whether nicotinamide (a form of vitamin B3/niacin) can slow or affect glaucoma progression. You may be eligible if you have newly diagnosed, untreated glaucoma or if you have treated glaucoma with measurable visual field changes.
StockholmAges 18 years+ - NCT05340647Recruiting
Study of micro-invasive glaucoma surgery options
This trial studies outcomes after certain minimally invasive glaucoma surgeries, including the Preserflo microshunt. It may help improve how safely and effectively glaucoma surgery is done, and how patients are followed afterward.
OsloAges 18 years+ - NCT05344651Recruiting
Compare two glaucoma drainage devices and cornea effects
This study compares two surgical drainage devices used for glaucoma and looks at how they affect the clear front window of the eye (the cornea). It may help you understand which device is gentler on the cornea over time.
RotterdamAges 18–100 - NCT05371977Recruiting
Deep sclerectomy or trabeculectomy for normal tension glaucoma
This trial compares two types of glaucoma surgery to lower pressure and protect vision in people with normal tension glaucoma. If your glaucoma is not well controlled on drops, you may be considered to help find which surgery works better and more safely.
HelsinkiAges 55–100 - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05405868RecruitingPhase 3
Nicotinamide for early to moderate open-angle glaucoma
This trial tests whether nicotinamide (a form of vitamin B3) can slow vision changes from open-angle glaucoma. It compares nicotinamide versus a placebo (inactive pill) in adults with early to moderate disease.
Belfast, Northern IrelandAges 18 years+ - NCT05426044RecruitingPhase 2
Metformin to protect the optic nerve in glaucoma
This study tests whether metformin can slow damage to the optic nerve in people with glaucoma. It uses eye scans and vision tests to look for changes over time, aiming to help preserve sight.
Wong Chuk HangAges 18 years+ - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT05626426Recruiting
Electrical stimulation for optic nerve damage from glaucoma
This trial studies whether electrical stimulation can help improve vision in people with glaucoma-related optic nerve damage. You may qualify if your visual field test shows moderate to severe loss and your eye pressure is stable.
Palo Alto, CaliforniaAges 18 years+ - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05710198RecruitingPhase 3
Citicoline eye drops to slow vision field loss in glaucoma
This Phase 3 trial tests whether citicoline 2% eye drops can help slow worsening of the visual field in adults with open-angle glaucoma. If you qualify, you would be monitored with repeated eye tests to see if your vision field stays more stable over time.
Milan, MIAges 18 years+ - NCT05753137Recruiting
Acupuncture along with glaucoma drops for mild or moderate glaucoma
This trial studies whether adding acupuncture to your usual glaucoma medication can help with glaucoma control in people with mild or moderate primary open-angle glaucoma. It compares acupuncture plus treatment versus treatment alone (randomly assigned).
TaichungAges 20 years+ - NCT05786196Recruiting
Testing canaloplasty surgery for mild to moderate glaucoma
This study tests how well a specific glaucoma surgery (canaloplasty) works on its own for people with mild to moderate primary open-angle glaucoma. It may help if drops (eye medicines) do not work well for you or you need fewer eye drops.
DüsseldorfAges 22 years+ - NCT05801471Recruiting
Tracking vision field changes in glaucoma patients
This study looks at different ways to measure how glaucoma affects your vision over time by comparing visual field results. It may help researchers find better models to track progression so treatment decisions can be made more accurately.
Milan, MilanoAges 40–90 - NCT05844384Recruiting
Testing a new eye drop bottle for glaucoma
This study checks whether a device called the Nanodropper helps deliver glaucoma medicine as well as standard use. It is for adults with stable primary open-angle glaucoma (or ocular hypertension) who are on a limited number of eye-pressure medicines.
Lackland Air Force Base, TexasAges 18 years+
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Common questions
- Are there clinical trials for glaucoma?
- Yes. Clin2 currently lists 209 recruiting glaucoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glaucoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glaucoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.