Clinical trials
Glaucoma clinical trials
Below are recruiting glaucoma clinical trials, each written for real people, not researchers. We’re tracking 201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00221897Recruiting
Eye test study to help diagnose glaucoma
This study tests new ways to evaluate eyes to help diagnose glaucoma and related eye conditions. You may be able to join if you’re an adult with normal eye health or with concerns like myopia, glaucoma suspicion, or ocular hypertension.
La Jolla, CaliforniaAges 18 years+ - NCT05426044RecruitingPhase 2
Metformin to protect the optic nerve in glaucoma
This study tests whether metformin can slow damage to the optic nerve in people with glaucoma. It uses eye scans and vision tests to look for changes over time, aiming to help preserve sight.
Wong Chuk HangAges 18 years+ - NCT05924477Recruiting
Compare glaucoma shunt options to prevent cell loss
This study compares a glaucoma drainage device approach to see which one better prevents loss of corneal cells after surgery. You may benefit by receiving close monitoring around the time of glaucoma surgery and helping doctors improve surgical choices.
San Francisco, CaliforniaAges 18 years+ - NCT05206877RecruitingPhase 1
Topical insulin eyedrops for glaucoma-related eye nerve damage
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
Palo Alto, CaliforniaAges 18 years+ - NCT05801471Recruiting
Tracking vision field changes in glaucoma patients
This study looks at different ways to measure how glaucoma affects your vision over time by comparing visual field results. It may help researchers find better models to track progression so treatment decisions can be made more accurately.
Milan, MilanoAges 40–90 - NCT05726058Recruiting
Imaging eye blood flow to assess glaucoma
This study uses special imaging to look at blood flow in the eye to help assess or better understand glaucoma. You may be eligible if you’re an adult with eye exams that fit the study’s specific eye-health and imaging requirements.
Baltimore, MarylandAges 18–88 - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05557721Enrolling by invitation
Micropulse laser for open-angle or pseudoexfoliation glaucoma
This study tests a specific eye laser treatment (micropulse) for people with open-angle or pseudoexfoliation glaucoma. It may help lower eye pressure, and the study also checks whether patients can follow the treatment plan and follow-up visits.
Skövde, Västra Götaland CountyAges 18 years+ - NCT05432245Enrolling by invitation
Glaucoma implant placed during cataract surgery
This trial looks at whether placing a small glaucoma implant at the same time as cataract surgery can better control eye pressure in people with primary open-angle glaucoma. It may help reduce the need for medicines or improve control, depending on how your eyes respond.
Panama CityAges 40 years+ - NCT05159960Enrolling by invitation
Repeat laser eye treatment study for eligible prior participants
This study is for people who already joined an earlier selective laser eye treatment trial and were able to be followed without needing stronger additional treatments. It looks at the best plan for repeating the laser treatment when appropriate.
Skövde, Västra Götaland CountyAges 18 years+ - NCT04519619Recruiting
Safety study of aflibercept eye injections in Japanese glaucoma patients
This trial checks how safe aflibercept (eye injection) is for Japanese people with neovascular glaucoma. You may be able to join if you already received aflibercept treatment under the approved Japanese instructions and have the correct diagnosis.
Multiple LocationsAges Any age - NCT04401982RecruitingPhase 4
Testing eye drops for blood flow in high eye pressure and glaucoma
This study tests whether three different eye drop treatments (netarsudil, latanoprost, or both together) can improve blood flow to the white part of the eye and the retina. It may help people with high eye pressure or who are glaucoma suspects better understand how these treatments work.
Baltimore, MarylandAges 18 years+ - NCT04354545Recruiting
Testing treatments for eye discomfort in glaucoma
This trial studies how to treat eye surface discomfort in people who have glaucoma and are already using multiple eye drops. It may help reduce symptoms like irritation while keeping glaucoma treatment on track.
Fountain Valley, CaliforniaAges Any age - NCT01957267Recruiting
Eye imaging study for glaucoma detection
This study uses advanced eye scans to compare the eyes of people with glaucoma against those with healthy eyes. It aims to find better ways to detect and monitor glaucoma, which could help preserve vision.
Portland, OregonAges 40–85 - NCT05136950Recruiting
Tracking side effects after secondary lens surgery for cataracts
This study follows children who had congenital cataract surgery to see how often glaucoma-related side effects happen after getting a secondary intraocular lens. It may help doctors better prevent and catch eye pressure problems after these surgeries.
GuangzhouAges 1.5 years–14 years - NCT05563623Recruiting
Study of people at risk for angle-closure progression
This study follows people who have eye anatomy that suggests a higher risk of angle closure, but who do not currently have high eye pressure or glaucoma damage. It aims to understand how often and how fast this risk can progress, which may help guide earlier monitoring or prevention.
Beijing, BeeijingAges 40–75 - NCT06077253Recruiting
Preventing angle closure glaucoma in Danish patients
This trial tests a laser treatment to prevent a type of glaucoma called angle closure. It is for people who have a narrow drainage angle in the eye but do not yet have glaucoma or other serious eye conditions.
AalborgAges 40–80 - NCT04957329RecruitingPhase 4
Latanoprost eye drops: with or without preservative
This study compares two versions of latanoprost eye drops—one that contains a preservative and one that is preservative-free. It aims to see how each version affects the eye’s “goblet cells,” which help keep the eye surface healthy.
Glostrup Municipality, DanmarkAges 18 years+ - NCT06243497Recruiting
Comparing eye fluid and tear markers before and after UCP
This study compares levels of inflammatory markers (cytokines) in the fluid inside your eye and your tears before and after a procedure called UCP (ultrasound cycloplasty) to treat glaucoma. It aims to understand how the eye responds, which may lead to better treatments for high eye pressure.
Guangzhou, GuangdongAges Any age - NCT02014389Recruiting
Testing pupil measurements with colored light in eye exams
This study checks how well a device can measure how your pupils respond to colored light. It may help improve eye testing, especially when monitoring certain vision and nerve conditions.
Tel LitwinskyAges 18–80 - NCT07816692Recruiting
iDose implant for open-angle glaucoma
This study tests a tiny implant, called iDose, that is placed in the eye during a short office procedure to help lower eye pressure in people with open-angle glaucoma or high pressure in the eye (ocular hypertension). It may offer a way to manage pressure without daily eye drops.
Austin, TexasAges 18 years+ - NCT07804277Recruiting
Comparing two eye pressure tests
This study compares two methods for measuring eye pressure—one using a standard device and one using a newer device—to see if they give similar results. It might help if you need a reliable, comfortable way to monitor your eye pressure.
Jacksonville, FloridaAges 22 years+ - NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT07780890Recruiting
Measuring eye hydration with light
This study uses a non-invasive imaging technique called Brillouin hydration mapping to measure hydration levels in different parts of the eye. It aims to help doctors better understand how hydration affects eye health and disease.
Boston, MassachusettsAges 20–79
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Common questions
- Are there clinical trials for glaucoma?
- Yes. Clin2 currently lists 201 recruiting glaucoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glaucoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glaucoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.