Clinical trials
GLP-1 clinical trials
Below are recruiting glp-1 clinical trials, each written for real people, not researchers. We’re tracking 88 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03878706Recruiting
Testing diabetes medicines on heart risk and heart failure
This trial studies how diabetes medicines (GLP-1 and SGLT2, alone or together) affect the heart in people with type 2 diabetes who are at higher cardiovascular risk and have heart failure with preserved pumping function. It may help find safer or more effective ways to reduce heart problems.
Athens, AtticaAges 45–80 - NCT07703683Recruiting
Muscle health in metabolic and hormone diseases
This trial looks at how muscle health is affected by metabolic or hormone disorders, aiming to find better markers for muscle loss called sarcopenia.
Woluwe-Saint-Pierre - Sint-Pieters-WoluweAges 18 years+ - NCT04575844RecruitingPhase 4
Exercise and GLP-1 to improve insulin and muscle blood flow
This study looks at whether doing exercise and a GLP-1 medicine (liraglutide or similar) can improve how your body uses insulin and how blood flows to your muscles. It is aimed at adults with metabolic syndrome who do not already have diabetes.
Charlottesville, VirginiaAges 21–60 - NCT04731272RecruitingPhase 2
Weekly GLP-1 medicine for blood sugar issues in adults with CF
This Phase 2 trial tests a weekly GLP-1 medicine (dulaglutide) to improve blood sugar control in adults with cystic fibrosis (CF) who have trouble managing glucose. It may help people with CF-related prediabetes or diabetes by improving how their body handles sugar.
Aurora, ColoradoAges 18 years+ - NCT05119179RecruitingPhase 4
Testing how genetics affect GLP-1 response in prediabetes
This study looks at how your genes may change how well a GLP-1–type medicine works to improve prediabetes. It focuses on adults at higher risk of developing diabetes, especially people of Mexican-American background.
Brownsville, TexasAges 18 years+ - NCT06256419Recruiting
Gene testing and exenatide response in Chinese type 2 diabetes patients
This study looks at how certain genes affect the risk of type 2 diabetes and how well the drug exenatide (a GLP-1 receptor agonist) works in Chinese patients. It aims to see if your genetic makeup can predict how you will respond to treatment.
Xuzhou, ChinaAges 25–70 - NCT07653412Recruiting
Genetic test for predicting weight loss drug response
This trial looks at whether your genes can predict how well you will respond to weight loss medications like semaglutide (Wegovy/Ozempic) or tirzepatide (Mounjaro). It may help doctors choose the right drug for you based on your DNA.
AthensAges 18 years+ - NCT07091500Recruiting
Exercise and a weight-loss drug for people with obesity
This trial tests whether combining a GLP-1 medication (a type of diabetes drug that also helps with weight loss) with an exercise program can improve physical function in people with obesity. If you are obese and have trouble with daily activities, this study may help you become more mobile and healthier.
St Louis, MissouriAges 50–75 - NCT06411210RecruitingPhase 2
Weight loss medication for young adults with type 1 diabetes
This study tests whether a GLP-1 medication (a type of drug that helps with weight loss) can safely and effectively help young adults with type 1 diabetes who also have obesity. It aims to see if adding this treatment to insulin can improve weight and blood sugar control.
New Haven, ConnecticutAges 18–30 - NCT07307235RecruitingPhase 4
Comparing a new diabetes combination to standard care for type 2 diabetes
This trial tests if a once-daily injectable combination (iGlarLixi) helps control blood sugar better than usual care for people with type 2 diabetes who are already taking diabetes pills. It aims to find a more effective treatment option.
Hefei, AnhuiAges 18 years+ - NCT07687589Enrolling by invitation
Testing a gut hormone for nausea in healthy adults
This study tests whether a natural gut hormone called GIP can reduce nausea by increasing blood flow to the gut. Researchers want to see how this works in healthy people.
HellerupAges 18–60 - NCT06734312Recruiting
Stomach procedure to maintain weight loss after GLP-1s
This study is for people who have lost weight using semaglutide or tirzepatide and are stopping that medication. It tests a stomach procedure (called mucosal ablation) to see if it can help you keep the weight off after stopping the drug.
Cary, North CarolinaAges 21–65 - NCT06839248Recruiting
Fasting before procedures with GLP-1 meds
This study looks at whether people taking weekly GLP-1 medications (like Ozempic or Wegovy) should follow standard fasting rules or a 24-hour clear liquid diet before a procedure. The goal is to find the safest way to prepare.
Melbourne, VictoriaAges 18 years+ - NCT06889454Recruiting
Heart and blood vessel changes in women with PCOS after treatment
This trial looks at how the heart's blood vessels and certain markers change in women with PCOS when they drink a sugary solution (OGTT). It checks these markers before treatment starts and again 6 and 12 months after, to help understand cardiovascular risk in PCOS.
ChaïdáriAges 18–45 - NCT06891287RecruitingPhase 1
Testing an oral GLP-1/2 capsule in healthy volunteers
This study tests a new oral capsule that delivers a medicine called PG-102, which is a dual GLP-1/2 agonist (similar to drugs used for diabetes and weight loss). It is for healthy volunteers to see how the body handles the medicine. The study has two parts: one for people with a lower BMI and one for people with a higher BMI (over 30).
Melbourne, VictoriaAges 18–65 - NCT06967558RecruitingPhase 2
GLP-1 hormone role in prediabetes
This study looks at how a hormone called GLP-1, made in the pancreas, affects blood sugar levels in people with borderline high blood sugar (prediabetes). It may help find new ways to prevent diabetes.
Rochester, MinnesotaAges 25–70 - NCT06981936RecruitingPhase 4
Do vitamins help prevent deficiencies while on weight-loss injections?
This trial tests if a daily multivitamin and mineral tablet can prevent nutrient shortages in people taking GLP-1 medicines (like Wegovy or Saxenda) for weight loss. You would take either the vitamin tablet or a placebo (a tablet with no active ingredients) for a year, to see which group has better nutrient levels.
AlexandriaAges 18–65 - NCT07083154RecruitingPhase 3
Testing a dual-action drug for diabetes and early memory loss
This study tests if a new type of diabetes drug that targets two natural hormones can help people with type 2 diabetes who also have early memory problems. If you have type 2 diabetes and mild cognitive impairment or mild dementia, this trial may offer a potential treatment option.
Changsha, HunanAges 50–75 - NCT07104539Recruiting
Strength training for people starting GLP-1 weight loss meds
This study looks at how strength training affects your muscles if you're just starting a GLP-1 medicine for weight loss (like Wegovy or Zepbound). It's designed to help understand if exercise can help preserve muscle while you lose weight.
Blacksburg, VirginiaAges 50 years+ - NCT07107334RecruitingPhase 2
GLP-1 drug plus hormone IUD for early endometrial cancer in obesity
This trial tests if adding a GLP-1 weight-loss drug to a hormone-releasing IUD can help treat very early endometrial cancer or a precancerous condition in women with obesity. The goal is to see if this combination is effective without surgery.
Gainesville, FloridaAges 18 years+ - NCT07210684Recruiting
Dihydroberberine for blood sugar, appetite, and mood in prediabetes
This study tests a supplement called dihydroberberine (DHB) to see if it helps improve blood sugar control, appetite, and mood in adults with prediabetes. You will wear a small sensor to track your blood sugar and use a phone app to record what you eat.
Addison, IllinoisAges 35–65 - NCT07221214RecruitingPhase 2
Testing a diabetes drug for drinking and heart health in HIV
This trial tests if a once-weekly diabetes medication (semaglutide) can help people with HIV reduce heavy drinking and improve heart health. It's for people who drink alcohol and have a higher body weight.
Nashville, TennesseeAges 18–89 - NCT07224334RecruitingPhase 1
How cells talk to adjust insulin for weight
This study looks at how cells in the pancreas communicate to help the body produce enough insulin when you have insulin resistance (weight-related). It tests a peptide to see how this communication works.
Durham, North CarolinaAges 18–60 - NCT07229170Recruiting
Taste changes and eating habits on weight loss drugs
This study looks at how GLP-1 medications (like semaglutide/Wegovy or tirzepatide/Mounjaro) change your sense of taste and eating habits while losing weight. If you are 18–60, have obesity, and have been taking one of these drugs for at least 12 weeks, you may qualify.
Roma, ItalyAges 18–60
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Common questions
- Are there clinical trials for glp-1?
- Yes. Clin2 currently lists 88 recruiting glp-1 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glp-1 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glp-1 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.