Clinical trials · Massachusetts
Heart failure clinical trials in Massachusetts
We’re tracking 57 recruiting heart failure studies with a site in Massachusetts — including Phase 2 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT06147336Recruiting
Testing the V-Lap system for heart failure monitoring
This trial tests a new device called V-Lap that is placed in the heart to monitor pressure. It may help doctors better manage heart failure and reduce hospital stays. Researchers want to see if it works well in people with mild to moderate heart failure.
Boston, MassachusettsAges 22–88 - NCT06793371RecruitingPhase 2
Study of CK-4021586 for heart failure with preserved ejection fraction
This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
Boston, MassachusettsAges 40–85 - NCT07112924Recruiting
CCM Heart Device Registry Study
This registry study follows patients who have or will get a CCM device to see how well it works and how safe it is over time. It helps doctors learn more about improving heart function in people with heart failure.
Boston, MassachusettsAges 18 years+ - NCT07215715Recruiting
Heart ultrasound study for older adults with heart failure
This study uses a special ultrasound to measure heart stiffness in people 60 and older who have heart failure with preserved or mildly reduced pumping function, with or without a condition called ATTR amyloidosis (a protein buildup in the heart). It also includes healthy controls.
Boston, MassachusettsAges 60 years+ - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Boston, MassachusettsAges Any age - NCT02610426Recruiting
Genetic testing to study who develops heart failure during breast cancer therapy
This study uses DNA genetic testing to find DNA changes that might explain why some people develop heart failure (CHF) after breast cancer treatment with certain medicines. It may help researchers understand risk and improve care for future patients.
Boston, MassachusettsAges Any age - NCT05604430Enrolling by invitation
Study of pre-hospital breathing support with a specific ventilator
This study looks at breathing support given outside the hospital using a particular ZOLL ventilator model and software version. If you were treated with the right equipment, the team will use the ventilator’s recorded data to evaluate how ventilation was delivered.
Uxbridge, MassachusettsAges Any age - NCT05388019Enrolling by invitation
VAD clinic visit study for new and returning patients
This trial looks at how well a specialized, multidisciplinary clinic works for people who have a ventricular assist device (VAD) and compares new VAD patients with those who have already had standard follow-up visits. It may help improve how care and check-ins are organized after your VAD is implanted.
Boston, MassachusettsAges 18 years+ - NCT06939751Recruiting
Testing microRNA levels to personalize heart transplant care
This trial is studying whether a blood test that measures small molecules called microRNAs can help doctors personalize the medicines used to prevent rejection after a heart transplant. If you qualify, you would help researchers learn how to better match immunosuppression to each patient's needs.
Boston, MassachusettsAges 18–99
Heart failure trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting heart failure studies listed above.
- Massachusetts General Hospital · 4 studies
- Boston Medical Center · 2 studies
- Brigham and Women's Hospital
- Dana-Farber Cancer Institute
- Eastern Cooperative Oncology Group
- Tufts Medical Center
- Uxbridge Fire
What taking part in a heart failure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Heart failure trials in other states
Common questions
- Are there heart failure clinical trials in Massachusetts?
- Yes. We're currently tracking 57 recruiting heart failure studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart failure study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart failure studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.