Clinical trials
High Risk clinical trials
Below are recruiting high risk clinical trials, each written for real people, not researchers. We’re tracking 923 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07725250Recruiting
AI-guided blood pressure trial for stage I-II hypertension
This study tests whether combining artificial intelligence with personalized medicine can help lower blood pressure in people with stage I or II hypertension (140/90 or higher). If you have high blood pressure and can walk without help, this trial may be for you.
La Jolla, CaliforniaAges 18 years+ - NCT07330804Recruiting
Gene study: CORIN and high blood pressure in Afro-Caribbeans
This study looks at whether a specific gene (CORIN) is linked to high blood pressure in people of Afro-Caribbean descent in Guadeloupe. It compares people with high blood pressure to healthy volunteers to see if the gene is more common in those with hypertension.
Petit-BourgAges 18 years+ - NCT06079424Recruiting
Artery aging risk markers study
This study looks at markers of artery aging in people already taking part in the Paris Prospective Study III. It may help understand how arteries change with age.
ParisAges 60–95 - NCT07588256Recruiting
AI Digital Health Platform for High Blood Pressure and Related Conditions
This study uses artificial intelligence and a digital health app to help manage high blood pressure, high cholesterol, diabetes, kidney disease, and heart disease. It aims to help people track their health at home and receive better care recommendations through technology.
New Taipei CityAges Any age - NCT05301101Recruiting
Re-irradiation planning for tumors near previously treated organs
This study tests a more personalized way to plan “re-irradiation,” meaning giving radiation again in an area that was already treated before. It aims to better calculate organ risk to reduce harmful side effects while treating cancer.
Milwaukee, WisconsinAges 18 years+ - NCT06452173Enrolling by invitation
Risk prediction for stroke in carotid artery narrowing
This study uses MRI scans to build a risk prediction model for stroke and other cerebrovascular events in people with carotid artery stenosis (narrowing of the neck arteries). By participating, you help doctors better understand who is at highest risk, which may lead to more personalized treatment.
Beijing, Beijing MunicipalityAges Any age - NCT07556562Recruiting
Early ovarian cancer detection through Pap test DNA analysis
This study tests whether DNA found in routine Pap smears can help detect ovarian cancer early in people at high genetic risk. Participants have inherited gene mutations that increase ovarian cancer risk and are considering preventive surgery.
Roma, RomaAges 18 years+ - NCT03264352RecruitingPhase 4
Treatment for slightly high blood pressure in type 2 diabetes
This trial tests an intervention to help adults with type 2 diabetes who have “high-normal” blood pressure (not severely high). If you qualify, you may learn whether this approach improves blood pressure and related health outcomes over time.
Guangzhou, GuangdongAges 45–79 - NCT07360561Enrolling by invitation
Mobile health game to boost physical activity for heart health
This study uses a smartphone app with game-like features to help you become more active over several months. Researchers want to see if this approach can improve heart health and lower risk factors for heart disease in university students and employees like you.
Bursa, NİLÜFERAges 18–65 - NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT06907862Recruiting
SWITCH trial: swapping processed soy foods in a heart-healthy diet
This study tests whether swapping highly processed soy foods for less processed soy foods, as part of a heart-healthy diet, can improve blood pressure, blood sugar, and weight in adults with obesity and high blood pressure. It may be a good option if you have type 2 diabetes and are already on stable medications.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for high risk?
- Yes. Clin2 currently lists 923 recruiting high risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.