Clinical trials
Hyperinsulinism clinical trials
Below are recruiting hyperinsulinism clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05088798RecruitingPhase 2
PET/MRI scan to help plan surgery for hyperinsulinism
This Phase 2 study uses special PET/MRI imaging to better understand a cause of hyperinsulinemic low blood sugar and guide whether surgery may help. It may help doctors choose the safest plan to reduce severe episodes and protect the brain.
St Louis, MissouriAges Any age - NCT06881992RecruitingPhase 3
Testing ersodetug for low blood sugar from neuroendocrine tumors
This study tests a new medicine called ersodetug in people whose neuroendocrine tumors cause dangerously low blood sugar that standard treatments can't control. If you need IV sugar or nutrition for at least a week, this trial may offer a new option to help manage your blood sugar.
Chicago, IllinoisAges 18 years+ - NCT02021604RecruitingPhase 1
Fluorodopa scan for congenital hyperinsulinism and insulinoma
This Phase 1 study tests a special imaging medicine (fluorodopa F 18) to help doctors better understand congenital hyperinsulinism (HI) patterns in the body. It may help guide treatment decisions to prevent dangerous low blood sugar and protect brain function.
Fort Worth, TexasAges Up to 18 years - NCT04205604RecruitingPhase 2
FDOPA PET scan to locate excess insulin in infancy
This Phase 2 study uses an FDOPA PET scan to find where insulin overproduction is coming from in focal congenital hyperinsulinism (FoHI) or related conditions. The goal is to help doctors better detect and localize the “source” so treatment can be more targeted.
San Francisco, CaliforniaAges birth–18 years - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT05662189Recruiting
PET scan study of beta cell function in diabetes
This study uses a special PET scan to measure how well insulin-producing cells (“beta cells”) in the pancreas are working in people with diabetes. It’s meant to help researchers understand diabetes biology and test whether the scan can reflect beta cell function.
Parma, PrAges 18–75 - NCT05753657RecruitingEarly Phase 1
Testing insulin and blood sugar monitoring with pioglitazone
This early study tests whether adding pioglitazone, along with close blood-sugar (glucose/insulin) monitoring, can help control high insulin and high blood sugar in people starting alpelisib for metastatic breast cancer. It may help reduce blood-sugar side effects from alpelisib.
HaifaAges 18–85 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05989347RecruitingPhase 1
Dapagliflozin with chemo for breast cancer
This trial tests whether adding the drug dapagliflozin (a pill that lowers blood sugar) to standard chemotherapy before breast cancer surgery can improve outcomes. It is for women with high insulin levels and a higher BMI who are about to start chemotherapy.
New Haven, ConnecticutAges 18 years+ - NCT06478121Recruiting
Understanding how genes affect beta cells
This study looks at how specific genetic changes affect beta cells, which make insulin. It may help people with rare genetic forms of diabetes or other beta cell disorders, and also needs healthy volunteers for comparison.
Exeter, DevonAges 6–99 - NCT06889454Recruiting
Heart and blood vessel changes in women with PCOS after treatment
This trial looks at how the heart's blood vessels and certain markers change in women with PCOS when they drink a sugary solution (OGTT). It checks these markers before treatment starts and again 6 and 12 months after, to help understand cardiovascular risk in PCOS.
ChaïdáriAges 18–45
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Common questions
- Are there clinical trials for hyperinsulinism?
- Yes. Clin2 currently lists 12 recruiting hyperinsulinism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperinsulinism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperinsulinism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.