Clinical trials · Philadelphia, PA
High blood pressure clinical trials in Philadelphia
We’re tracking 40 recruiting high blood pressure studies with a site in or near Philadelphia — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06062394Recruiting
Healthy Heart study for Penn Medicine patients
This trial tests if a combination of medication and lifestyle changes can lower cholesterol and prevent heart problems in people who are at risk or already have heart disease.
Philadelphia, PennsylvaniaAges 35–80 - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Philadelphia, PennsylvaniaAges 18–80 - NCT05587712RecruitingPhase 2
Sotatercept trial for children with pulmonary arterial hypertension
This Phase 2 trial tests sotatercept, a medicine that targets the blood-vessel changes in pulmonary arterial hypertension (PAH), in children. It may help improve how well the heart and lungs work by changing the underlying disease process.
Philadelphia, PennsylvaniaAges 1–17 - NCT02249923Recruiting
Children with pulmonary hypertension registry in Spanish or English
This registry study collects information from children and families affected by pulmonary hypertension to better understand the condition. It may help researchers track outcomes over time and improve future care.
Philadelphia, PennsylvaniaAges 1 day–21 years - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Camden, New JerseyAges 18–80 - NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Wynnewood, PennsylvaniaAges 18–85 - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Media, PennsylvaniaAges 18 years+ - NCT06297291Recruiting
Long-term safety study for a kidney nerve treatment
This study tests a device that uses ultrasound to calm overactive kidney nerves, which may help lower blood pressure. It is for people with high blood pressure that is hard to control with medication.
Marlton, New JerseyAges 18 years+ - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Berlin, New JerseyAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
West Chester, PennsylvaniaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Wilmington, DelawareAges birth–20 years - NCT07071077Recruiting
Storytelling for blood pressure control
This study tests whether sharing personal stories about managing high blood pressure can help African American adults better control their condition. You may join if you have high blood pressure, take medication for it, and are interested in trying a storytelling approach.
Newark, DelawareAges 18 years+ - NCT06094816RecruitingPhase 4
Brain MRI study on salt and blood pressure
This study uses MRI scans to look at how the brain controls salt and blood pressure. It is for people aged 40–60 with normal to slightly high blood pressure, who have no major health conditions.
Newark, DelawareAges 40–60 - NCT07049783Recruiting
How exercise timing affects blood pressure response
This study looks at how the time of day you exercise affects your blood pressure response. It is for young adults with slightly elevated blood pressure who are generally healthy, not on certain medications, and do not have sleep or chronic health issues.
Newark, DelawareAges 18–39
Hear when a new High blood pressure trial opens near Philadelphia, PA
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High blood pressure trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting high blood pressure studies listed above.
- University of Delaware · 3 studies
- Alfred I. DuPont Hospital for Children
- Cardiology Consultants of Philadelphia
- CenExel HRI
- Children's Hospital of Philadelphia
- Children's Hospital of Philadelphia (CHOP) ( Site 1608)
- Cooper University Hospital
- Hospital of the University of Pennsylvania
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in Pennsylvania.
Common questions
- Are there high blood pressure clinical trials near Philadelphia?
- Yes. We're currently tracking 40 recruiting high blood pressure studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.