Clinical trials · Philadelphia, PA
High blood pressure clinical trials in Philadelphia
We’re tracking 40 recruiting high blood pressure studies with a site in or near Philadelphia — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06642246Recruiting
Sleep Help for Kids with High Blood Pressure
This study tests whether helping teens with high blood pressure get more sleep can lower their blood pressure. It offers a sleep-focused program and checks if it helps within a few months.
Philadelphia, PennsylvaniaAges 13–18 - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05442671Recruiting
Exercise coaching program for children with pulmonary hypertension
This trial tests whether a structured exercise program, done with remote support, is safe and helpful for children with pulmonary hypertension. It aims to improve how well kids function day-to-day while they stay on their usual PH medications.
Philadelphia, PennsylvaniaAges 8–18 - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Camden, New JerseyAges 18–80 - NCT07288398RecruitingPhase 3
Levosimendan for exercise limitation in PH-HFpEF
This trial tests if the drug levosimendan can help people with a specific type of pulmonary hypertension (PH-HFpEF) feel less tired and breathless during daily activities, and improve their exercise ability.
Wynnewood, PennsylvaniaAges 18–85 - NCT07076303Recruiting
Laser treatment for new glaucoma patients without prior medication
This study tests a new laser treatment called DSLT for people who have just been diagnosed with open-angle glaucoma or a similar condition like ocular hypertension. It aims to see if the laser can lower eye pressure by at least 20% after six months without needing any eye drops.
Plymouth Meeting, PennsylvaniaAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Media, PennsylvaniaAges 18 years+ - NCT07222917RecruitingPhase 2
Dapagliflozin with baxdrostat for kidney disease and high blood pressure
This trial tests if adding dapagliflozin to baxdrostat (a new blood pressure drug) reduces protein in urine better than baxdrostat alone in people with chronic kidney disease and high blood pressure. It aims to find a more effective way to protect kidney health.
Media, PennsylvaniaAges 18 years+ - NCT06297291Recruiting
Long-term safety study for a kidney nerve treatment
This study tests a device that uses ultrasound to calm overactive kidney nerves, which may help lower blood pressure. It is for people with high blood pressure that is hard to control with medication.
Marlton, New JerseyAges 18 years+ - NCT07543120RecruitingPhase 2
Extended Safety Study of QCZ484 Blood Pressure Medication
This is a continuation study for people who completed a previous QCZ484 trial and tolerated it well. Researchers will monitor how safe and effective the medication remains with longer-term use for managing high blood pressure.
Berlin, New JerseyAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Wilmington, DelawareAges birth–20 years - NCT06094816RecruitingPhase 4
Brain MRI study on salt and blood pressure
This study uses MRI scans to look at how the brain controls salt and blood pressure. It is for people aged 40–60 with normal to slightly high blood pressure, who have no major health conditions.
Newark, DelawareAges 40–60 - NCT07071077Recruiting
Storytelling for blood pressure control
This study tests whether sharing personal stories about managing high blood pressure can help African American adults better control their condition. You may join if you have high blood pressure, take medication for it, and are interested in trying a storytelling approach.
Newark, DelawareAges 18 years+ - NCT07049783Recruiting
How exercise timing affects blood pressure response
This study looks at how the time of day you exercise affects your blood pressure response. It is for young adults with slightly elevated blood pressure who are generally healthy, not on certain medications, and do not have sleep or chronic health issues.
Newark, DelawareAges 18–39
Hear when a new High blood pressure trial opens near Philadelphia, PA
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High blood pressure trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting high blood pressure studies listed above.
- University of Delaware · 3 studies
- Children's Hospital of Philadelphia · 2 studies
- Research Site · 2 studies
- University of Pennsylvania · 2 studies
- Virtua Health · 2 studies
- Abington Memorial Hospital
- Alfred I. duPont Hospital for Children
- CenExel HRI / Hassman Research Institute
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in Pennsylvania.
Common questions
- Are there high blood pressure clinical trials near Philadelphia?
- Yes. We're currently tracking 40 recruiting high blood pressure studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.