Clinical trials · Pennsylvania
High blood pressure clinical trials in Pennsylvania
We’re tracking 47 recruiting high blood pressure studies with a site in Pennsylvania — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06281665RecruitingPhase 4
Aspirin after preeclampsia: the TAP trial
This trial tests whether taking low-dose aspirin after giving birth can help people who had preeclampsia. It aims to see if aspirin can lower the risk of future heart problems.
Pittsburgh, PennsylvaniaAges 18–55 - NCT04071327Recruiting
Pulmonary hypertension registry for patient experiences
This trial is a registry that collects health information from people with pulmonary hypertension to better understand the disease and improve care. You may be asked to share details about your diagnosis and visits, especially soon after you start seeing a specialized PH care center.
Pittsburgh, PennsylvaniaAges birth+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07175038RecruitingPhase 2
Study of a new pill for pulmonary hypertension
This study tests a new pill, ROC-101, for people with pulmonary hypertension (high blood pressure in the lungs). It aims to see if the pill can improve symptoms and daily function.
Philadelphia, PennsylvaniaAges 18–80 - NCT07599579Recruiting
Mobile app to manage high blood pressure after pregnancy complications
This study tests a smartphone app to help women who had high blood pressure during pregnancy manage their blood pressure now, 10–20 years later. The goal is to see if the app helps keep blood pressure under control and reduces heart disease risk.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Mechanicsburg, PennsylvaniaAges 18–85 - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Pittsburgh, PennsylvaniaAges 14–35 - NCT06388421Recruiting
PH-ILD patient registry: tracking real-world outcomes
This study tracks people with both lung scarring and high blood pressure in the lungs (Group 3 PH-ILD) to better understand the disease and how treatments like Tyvaso work in real life. It may help you and your doctor make more informed decisions about your care.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06059638Recruiting
Pacemaker pacing for blood pressure control
This study tests whether adjusting the timing of a pacemaker can help lower blood pressure in people who already have or need a pacemaker. It could be an option for those whose blood pressure is not well controlled with medication.
Doylestown, PennsylvaniaAges 18 years+ - NCT05798923RecruitingPhase 2
Study of a new drug for pulmonary hypertension with lung disease
This trial tests an investigational drug called LAM-001 for people who have pulmonary hypertension (high blood pressure in the lungs) along with a type of lung disease called interstitial lung disease. The drug may help improve symptoms and daily function. This study will see if the drug is safe and helpful for this condition.
Philadelphia, PennsylvaniaAges 18–85 - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Camp Hill, PennsylvaniaAges 18 years+ - NCT07481981RecruitingPhase 3
Study of once-daily inhaled TPIP for pulmonary arterial hypertension
This trial tests an inhaled medication (TPIP) that opens blood vessels in the lungs to help you breathe easier and be more active. It is for people with PAH who are already on stable treatment and have moderate symptoms.
Philadelphia, PennsylvaniaAges 18–75 - NCT02249923Recruiting
Children with pulmonary hypertension registry in Spanish or English
This registry study collects information from children and families affected by pulmonary hypertension to better understand the condition. It may help researchers track outcomes over time and improve future care.
Philadelphia, PennsylvaniaAges 1 day–21 years - NCT07298694Enrolling by invitation
Choosing a hypertension medication with helpful defaults
This trial tests whether changing the default options in doctors' ordering systems can help patients get the best medication for high blood pressure. You may be eligible if you are an adult who recently received a prescription for a common blood pressure drug at a participating clinic.
Danville, PennsylvaniaAges 18 years+ - NCT07209254Recruiting
Two smartphone plans to manage high blood pressure after childbirth
This study tests whether two different mobile-health tools can help new mothers keep their blood pressure under control in the first weeks after giving birth. It is designed for women who were diagnosed with a blood pressure condition during pregnancy and need medication after delivery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07179380RecruitingPhase 3
Inhaled treprostinil for pulmonary hypertension related to interstitial lung disease
This study tests an inhaled powder medication called TPIP (treprostinil palmitil inhalation powder) to see if it can improve symptoms and exercise ability in people who have both interstitial lung disease and pulmonary hypertension. The study will compare TPIP against a placebo (a dummy treatment without the active drug) to understand how well it works and if it is safe.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06950099Recruiting
Advanced Brain Scans for IIH Patients Planning Stenting
This study uses advanced brain scans (MRIs) to look at the veins in your brain to help plan a stenting procedure for patients with Idiopathic Intracranial Hypertension (IIH) that is not improving with standard care.
Philadelphia, PennsylvaniaAges 18–55 - NCT07151768Recruiting
Validating a risk score for lung disease patients with pulmonary hypertension
This study is testing whether a new risk score can better predict outcomes for people who have both chronic lung disease and pulmonary hypertension (high blood pressure in the lungs). If you qualify, the researchers will follow your health over time to see how well the score works.
Philadelphia, PennsylvaniaAges 18–99 - NCT07041281RecruitingPhase 2
Spironolactone to improve postpartum blood pressure after pregnancy hypertension
This study tests whether the medication spironolactone can help manage high blood pressure after delivery in people who had gestational hypertension or preeclampsia. It may help prevent long-term heart problems.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06911632Recruiting
AI-assisted check for pulmonary hypertension in interstitial lung disease
This study uses an AI tool to help doctors decide if you should be tested for pulmonary hypertension (high blood pressure in the lungs), which can be a complication of interstitial lung disease. If the tool suggests you might have it, you may get an echocardiogram (an ultrasound of the heart) and a right heart catheterization (a test to measure pressure in the heart) to find out for sure.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
Pittsburgh, PennsylvaniaAges 22 years+ - NCT06642246Recruiting
Sleep Help for Kids with High Blood Pressure
This study tests whether helping teens with high blood pressure get more sleep can lower their blood pressure. It offers a sleep-focused program and checks if it helps within a few months.
Philadelphia, PennsylvaniaAges 13–18 - NCT06559891Recruiting
Ultrasound treatment for high blood pressure
This trial tests an ultrasound device that targets nerves around the kidney to lower blood pressure. It may help people whose blood pressure is not well controlled with medication.
Philadelphia, PennsylvaniaAges 22–75
High blood pressure trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting high blood pressure studies listed above.
- University of Pennsylvania · 4 studies
- Temple University Hospital · 3 studies
- Allegheny Health Network · 2 studies
- Children's Hospital of Philadelphia · 2 studies
- University of Pittsburgh Magee-Womens Hospital · 2 studies
- University of Pittsburgh Medical Center · 2 studies
- Clinical Trial Site
- Geisinger Medical Center
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in Pennsylvania?
- Yes. We're currently tracking 47 recruiting high blood pressure studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.