Clinical trials
High blood pressure clinical trials
Persistently raised blood pressure, a major risk factor for heart disease and stroke. We’re tracking 980 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06512935Recruiting
Ventilator study for preterm infants with lung recovery
This study tests a new way of setting the ventilator for preterm babies born before 34 weeks who are still on a breathing machine. It aims to improve lung healing and heart function by finding the best pressure settings. The results could help your baby breathe more comfortably.
Birmingham, AlabamaAges 1 week–4 weeks - NCT06485700Recruiting
Peer support and texting for blood pressure control
This study tests a program that uses peer support and text messages to help you keep your blood pressure under control. The goal is to make it easier to stick with your treatment plan and improve your health.
Webuye, Bungoma CountyAges 18 years+ - NCT06475781RecruitingPhase 2
Study of mirivadelgat for pulmonary hypertension with interstitial lung disease
This study tests a new medication called mirivadelgat for people with pulmonary hypertension associated with interstitial lung disease (PH-ILD). The goal is to see if it can help improve symptoms and slow the progression of the disease.
Banja LukaAges 18–85 - NCT06462287RecruitingPhase 2
Testing a substance P blocker for high blood pressure and sleep apnea
This study tests if a drug that blocks substance P can lower a hormone called aldosterone in people with both severe sleep apnea and high blood pressure. If you have these conditions, this trial may help find a new treatment option.
Rouen, FranceAges 18–75 - NCT05413057Recruiting
Testing blood pressure pills with two or three medicines
This trial studies whether fixed-dose blood pressure medicines—either two drugs (fimasartan + amlodipine) or three drugs (fimasartan + amlodipine + hydrochlorothiazide)—work well and are safe. It may help your care team compare how these combinations control blood pressure and what side effects occur.
SeoulAges 19 years+ - NCT04459806Recruiting
Study dose timing to improve care for brain injury
This trial studies how to time medication or treatment doses when a person has serious brain injury, using measurements from a pressure monitor in the skull. It may help doctors manage brain swelling and pressure more effectively.
Monza, MBAges 18–80 - NCT06432582Recruiting
Liver disease blood marker study for people with stiff livers
This study looks at whether certain micro-RNA levels in your blood can help predict how your chronic liver disease is progressing. It is for people who already have some liver stiffness (measured by a special ultrasound) and are being treated at the University Hospital St. Pölten.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT06402968Recruiting
Clevidipine for treating high blood pressure after a brain bleed
This trial tests a blood pressure medicine called clevidipine given through an IV to people with a brain bleed (intracerebral hemorrhage). The goal is to see if quickly lowering blood pressure helps prevent more bleeding and improve recovery.
Irvine, CaliforniaAges 18–100 - NCT06409585Recruiting
Heart muscle disease imaging study for scarring
This study uses advanced imaging (PET/MR or PET/CT) to look at scarring (fibrosis) in the heart muscle. It is for people with various heart muscle diseases, including heart failure with preserved pumping, thickened heart muscle, high blood pressure-related heart damage, heart inflammation, and others.
Edinburgh, ScotlandAges 30–90 - NCT06397456Recruiting
Kidney education program for Black patients in the hospital
This study tests whether a special education and referral program helps Black patients with advanced kidney disease learn about their treatment options before they need dialysis or a transplant. If you join, you will get extra support while you're in the hospital.
Chicago, IllinoisAges 18–70 - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06346886Recruiting
App for blood pressure control in African Americans
This study tests whether a smartphone app can help African American adults with high blood pressure better manage their condition and improve heart health. You'll use the app regularly and share your progress.
Rochester, MinnesotaAges 18 years+ - NCT06352619Recruiting
Lowering blood pressure after clot removal for stroke
This trial tests whether lowering blood pressure soon after a clot-removal procedure for stroke can improve recovery. It is for people whose blood pressure remains high after the procedure.
Sydney, New South WalesAges 18 years+ - NCT05067998Recruiting
Natural medicine and vitamin IV study for overall health
This study looks at whether natural medicine, vitamin IV fluids, and supplements can help people maintain good health. There don’t appear to be specific eligibility limits listed, so many people may be able to join, but you’d still need screening by the study team.
Dover, DelawareAges 21–80 - NCT05719415Recruiting
Testing balloon treatment effects on lung blood-vessel surface area
This study looks at how a procedure called balloon pulmonary angioplasty changes measurements in lung blood vessels in people with chronic thromboembolic pulmonary hypertension. It may help doctors understand what changes the treatment makes and why.
Montreal, QuebecAges 18–75 - NCT06325800Recruiting
Heart and blood vessel health registry
This study collects information from people at risk for heart disease, stroke, or kidney problems to better understand how to prevent these conditions. If you join, you'll be helping doctors learn more about how to keep blood vessels healthy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06333652RecruitingPhase 2
Ravulizumab for severe pregnancy hypertension disorders
This study tests a medicine called Ravulizumab for pregnant people with severe high blood pressure problems (preeclampsia or HELLP syndrome) before 34 weeks of pregnancy. The goal is to see if the drug can help manage the condition and improve outcomes for both mother and baby.
Rochester, MinnesotaAges 18–50 - NCT06299436Recruiting
Heart muscle function testing in right heart failure
This trial studies how the right side of the heart works in people with heart failure. It uses special monitoring to understand muscle function and may help doctors find better ways to treat right heart failure.
Baltimore, MarylandAges 18–90 - NCT03267615Recruiting
Study in advanced liver scarring using pressure and stiffness tests
This study looks at people over 18 who have advanced, long-term liver scarring. It uses specialized measurements of liver stiffness and pressure to confirm eligibility and may help doctors better understand this condition.
ViennaAges 18–100 - NCT05644548Recruiting
Eye scan study for people with common health conditions
This study uses a special eye scan (OCTA) to look at how blood vessels in the retina change in people with conditions like high blood pressure, diabetes, or abnormal cholesterol. It may help doctors better understand how these common illnesses affect the eyes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06286891Recruiting
Frailty and lung function after pulmonary endarterectomy
This study looks at how frailty, physical ability, and lung function change in people who have had surgery to remove blood clots from the lungs (pulmonary endarterectomy). It aims to help doctors better understand recovery after this procedure.
São Paulo, São PauloAges 18 years+ - NCT06256991RecruitingPhase 4
Potassium management for kidney health
This study tests if careful potassium management can help people with chronic kidney disease (CKD) safely take higher doses of blood pressure medicines called ACE inhibitors or ARBs, which are known to protect the kidneys. You may be eligible if you have moderate to advanced CKD and are already on a moderate dose of one of these medications.
GroningenAges 18 years+ - NCT06261398Recruiting
Better pregnancy outcomes with text support
This trial uses text messages and education to help improve pregnancy outcomes for women who are less than 21 weeks pregnant. It's designed for patients receiving care at certain Ohio State University clinics.
Columbus, OhioAges 18 years+ - NCT06265272Recruiting
PSMA-11 PET/MRI for Liver Cirrhosis
This study uses a special PET/MRI scan with a tracer called PSMA-11 to look at how liver cirrhosis affects the liver. It may help doctors better understand and monitor the disease.
Charlestown, MassachusettsAges 18–99
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Common questions
- Are there clinical trials for high blood pressure?
- Yes. Clin2 currently lists 980 recruiting high blood pressure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a high blood pressure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.