Clinical trials
Hypertriglyceridemia clinical trials
Below are recruiting hypertriglyceridemia clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06822790RecruitingPhase 3
Long-term safety of plozasiran for high triglycerides
This long-term study tests the safety and effectiveness of plozasiran for people with very high triglycerides. It's for those who already completed a previous plozasiran study and want to continue treatment.
Bakersfield, CaliforniaAges 18 years+ - NCT07388420Recruiting
Evolocumab for pancreatitis from high triglycerides
This trial tests adding evolocumab, a medicine that lowers fats in the blood, to standard treatment for people hospitalized with pancreatitis caused by very high triglycerides. The goal is to see if it helps improve recovery.
Shenyang, LiaoningAges 18–75 - NCT07308392RecruitingPhase 2
Testing HRS-7249 and SHR-1918 for severe high triglycerides at risk of pancreatitis
This trial tests two experimental drugs, HRS-7249 and SHR-1918, to lower very high triglyceride levels in people who are at high risk for pancreatitis. It aims to see if these drugs can reduce the risk of pancreatitis attacks.
Nanjing, JiangsuAges 18–80 - NCT06880770RecruitingPhase 3
Study of plozasiran for severe high triglycerides with pancreatitis
This study tests an investigational drug called plozasiran for people with severely high triglycerides that have already caused pancreatitis (inflammation of the pancreas). The goal is to see if the drug can lower triglycerides and help prevent future attacks.
Los Angeles, CaliforniaAges 18 years+ - NCT07491172RecruitingPhase 1
Trial of CTX310 for stubborn high cholesterol and fats
This trial tests a new medicine, CTX310, for people with persistently high levels of fats (triglycerides) and cholesterol that have not improved with standard treatments. It aims to see if the drug is safe and tolerable.
Hialeah, FloridaAges 18–75 - NCT05743868Recruiting
Study of how insulin resistance affects blood fats
This study looks at how differences in insulin resistance may change how the liver makes triglycerides (a type of blood fat). It may help researchers understand why some people have higher triglycerides and how to target them better.
AmsterdamAges 18–65 - NCT06564584RecruitingPhase 2
Study of TLC-2716 for high triglycerides and fatty liver disease
This trial tests an investigational drug called TLC-2716 for people with very high triglycerides and a type of fatty liver disease (NAFLD or NASH). The goal is to see if it is safe and can help lower fat levels in the blood and liver.
Guadalajara, JaliscoAges 18–70 - NCT07269210RecruitingPhase 2
Solbinsiran for severe high triglycerides
This study tests a new medicine called solbinsiran (LY3561774) for people with very high triglyceride levels. It aims to see if it can lower these fats in your blood and reduce the risk of pancreatitis or heart problems.
Phoenix, ArizonaAges 18 years+ - NCT07140809RecruitingPhase 1/Phase 2
Study of JMT202 for people with high triglycerides
This trial tests a new injectable drug, JMT202, for people with high triglycerides (a type of fat in the blood). The goal is to see if it safely lowers triglycerides and may reduce heart risk.
Beijing, Beijing MunicipalityAges 18–75 - NCT07349615RecruitingPhase 3
Study of SHR-1918 for high triglycerides
This trial tests a new medication, SHR-1918, to lower high triglyceride levels. It may be an option for people with moderately elevated triglycerides and controlled cholesterol.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07508930Recruiting
Russian extreme high triglycerides registry
This study creates a registry for people with very high triglycerides (≥10 mmol/L). It aims to understand who gets this condition and how it affects them over time.
AstrakhanAges Any age - NCT07604974RecruitingPhase 2
Safety and effectiveness of ION775 for very high triglycerides
This trial tests a new medicine called ION775 to help lower very high triglyceride levels in the blood. Triglycerides are a type of fat, and having too much can increase heart disease risk. The study will check if ION775 is safe and actually works when added to your regular cholesterol medications.
Lincoln, CaliforniaAges 18 years+ - NCT07050134Enrolling by invitation
Study of DR10624 for high triglycerides and carotid artery plaque
This trial tests a new drug, DR10624, to see if it can lower high triglycerides and reduce plaque in the carotid artery (the main artery in your neck). It may help people with both conditions who are also overweight.
Hefei, AnhuiAges 18–65 - NCT06976099Enrolling by invitation
Studying pancreatitis caused by high triglycerides
This study looks at people with acute pancreatitis caused by very high blood fat levels (triglycerides). It aims to collect information to better understand and treat this condition.
Beijing, Beijing MunicipalityAges 18–80 - NCT07028749RecruitingPhase 2
Study of an experimental drug for high triglycerides and remnant cholesterol
This trial tests an investigational medication, MAR001, to see if it can lower high levels of fats in the blood (triglycerides and remnant cholesterol) linked to heart disease. If you have these conditions, this treatment might help reduce your risk.
Anniston, AlabamaAges 18–75 - NCT07720232RecruitingPhase 4
Probiotic plus lipid-lowering for pancreatitis from high triglycerides
This trial tests if adding a probiotic (Bacillus subtilis and Enterococcus faecium) to standard lipid-lowering therapy helps people with mild pancreatitis caused by very high triglycerides. It aims to see if the combination reduces inflammation and speeds recovery.
Xiamen, FujianAges 18–65 - NCT06451770RecruitingPhase 1
Testing VERVE-201 for stubborn high cholesterol or triglycerides
This trial tests a new one-time treatment called VERVE-201 for people with very high cholesterol or triglycerides that don't get better with standard medicines. The goal is to see if it can safely lower these fats in your blood.
Clearwater, FloridaAges 18–70 - NCT05860569RecruitingPhase 1
Gene therapy safety study for inherited high triglycerides and pancreatitis
This Phase 1 trial tests the safety of a gene therapy for people with inherited, hard-to-control high triglycerides (fat in the blood) who have had pancreatitis episodes. It may help by targeting the genes involved in triglyceride control, but the main goal here is to check safety and tolerability.
Beijing, Beijing MunicipalityAges 18–60 - NCT06206759Recruiting
Vitamin C for triglyceride levels in ICU patients
This trial looks at whether giving vitamin C through an IV can help lower triglyceride levels in patients in the intensive care unit. It compares patients who received vitamin C with similar patients who did not.
Kfar SabaAges 18–99 - NCT06494488RecruitingEarly Phase 1
Testing how omega-3s affect heart health and blood clotting
This study tests whether two types of omega-3s (EPA and DHA) help improve HDL (good cholesterol) and reduce blood clot risk in people with high triglycerides and low HDL cholesterol.
Providence, Rhode IslandAges 18–69 - NCT07004777Recruiting
Eating fatty fish or nuts to lower triglycerides
This study tests if eating foods rich in omega-3 fats (like fish and nuts) can lower your triglycerides and improve cholesterol levels. It may help if you have moderately high triglycerides but no other serious health conditions.
Mexico City, Mexico CityAges 18 years+ - NCT07199309RecruitingPhase 2
Study of MAR001 for people with high triglycerides and remnant cholesterol
This study tests a new medicine called MAR001 in people with high triglycerides and remnant cholesterol, which are types of fats in the blood. It aims to see if the medicine can improve these levels while you stick to your usual diet and medications.
Chula Vista, CaliforniaAges 18–75 - NCT07200674Recruiting
Measuring blood thinner activity in fatty samples
This trial tests a faster spinning method to measure how well your blood thinner (anti-Xa) is working when your blood sample is fatty. It may help ensure accurate results for patients on certain anticoagulants.
StrasbourgAges 18 years+
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Hypertriglyceridemia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for hypertriglyceridemia?
- Yes. Clin2 currently lists 23 recruiting hypertriglyceridemia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypertriglyceridemia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypertriglyceridemia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.