Clinical trials
Hypothermia clinical trials
Below are recruiting hypothermia clinical trials, each written for real people, not researchers. We’re tracking 48 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07421882Recruiting
Cooling after cardiac arrest to improve brain recovery
This trial tests if starting body cooling before reaching the hospital can help protect the brain after a cardiac arrest. It is for adults who are unconscious after their heartbeat has been restored by emergency services.
SingaporeAges 16–80 - NCT07275021Recruiting
Brain Injury & Vision Screening in Newborns
This study looks for early signs of vision problems in babies who had brain injuries around the time of birth. It aims to help doctors better identify and predict these issues.
Boston, MassachusettsAges 7 months–10 months - NCT07244354Enrolling by invitation
Maternal warmth after C-section and recovery
This study looks at whether keeping mothers warm after a C-section helps them recover faster. It compares standard care with a warmer blanket to see if it reduces shivering and improves comfort.
Oslo, OsloAges 18–50 - NCT07219290Enrolling by invitation
Lung function study based on birth order in the litter
This study looks at how your lung function might be related to your position in your mother's litter. It may help us understand more about breathing health.
Fresno, CaliforniaAges 18–65 - NCT07137143Recruiting
Warming the ICU room after abdominal surgery
This study tests how warming the intensive care room after your abdominal surgery affects your recovery. It includes patients who are in the ICU after planned surgery and have no major health problems that affect body temperature.
Adana, YüreğirAges 18 years+ - NCT07086703Recruiting
Temperature management after in-hospital cardiac arrest
This trial compares two ways of controlling body temperature after a cardiac arrest that happens in the hospital: cooling to 91.4°F (33°C) versus keeping a normal temperature. The goal is to see which approach helps patients recover better.
Ghent, BelgiumAges 18 years+ - NCT07071480Recruiting
Noninvasive sound therapy for chronic tinnitus
This trial tests a noninvasive device to reduce the loudness and burden of chronic tinnitus. It may help people who have constant tinnitus and are not currently using other treatments.
Miami, FloridaAges 18 years+ - NCT07028372Recruiting
Long-term follow-up of cardiac arrest survivors who had ultra-rapid cooling
This trial checks on the long-term health of people who survived a cardiac arrest and received ultra-rapid cooling as part of an earlier study (OverCool). The goal is to see how they are doing over time.
AngersAges 18 years+ - NCT07017998Recruiting
External device therapy for constant tinnitus
This study tests a new external device designed to help manage constant tinnitus. It is for adults aged 18–55 who have had bothersome ringing in their ears for at least a month and are not currently receiving other tinnitus treatments.
Bozeman, MontanaAges 18–55 - NCT06986967Recruiting
Comparing Blood Flow Methods During Aortic Arch Surgery
This study compares two methods of supplying blood to the brain during surgery on the main artery from the heart (aorta) and the aortic arch. It may help determine the safest way to protect the brain during cooling and surgery.
Durham, North CarolinaAges 18 years+ - NCT06788925Enrolling by invitation
Testing the Therm'Up heating device for trauma patients
This trial tests a new heating device called 'Therm'Up' to see if it can help prevent or treat hypothermia (dangerously low body temperature) in people who have had a serious injury, are bleeding, have burns, or are stuck in the cold. The goal is to keep patients warm during the time it takes to get them to the hospital.
ÉchirollesAges 18 years+ - NCT06776549Recruiting
Cooling or normal temperature after cardiac arrest with ECMO
This trial tests if cooling the body (hypothermia) or keeping normal body temperature (normothermia) after emergency heart-lung support (ECMO) improves survival in adults who had a cardiac arrest outside the hospital.
Kurume, FukuokaAges 18–75 - NCT06579248RecruitingEarly Phase 1
Cooling device to protect taste during radiation
This trial tests a special mouthpiece that cools the tongue during radiation therapy for advanced larynx cancer. It may help prevent taste loss caused by treatment.
Detroit, MichiganAges 18 years+ - NCT06375278Recruiting
Cooling device to protect hearing during cochlear implant
This trial tests a special cooling device used during cochlear implant surgery to help protect any remaining hearing you have. It may be a good option if you are already planning to get a cochlear implant at the University of Miami.
Miami, FloridaAges 18 years+ - NCT06256354Recruiting
Managing body temperature during cancer surgery to prevent confusion
This trial tests whether carefully managing a patient's body temperature during cancer surgery can reduce the risk of postoperative delirium and improve long-term survival. It is for older adults undergoing major cancer surgery.
Chizhou, AnhuiAges 65 years+ - NCT06025123Recruiting
Cooling treatment for cardiac arrest before hospital
This trial tests whether cooling the brain through the nose right after a cardiac arrest improves survival. Paramedics will start a cooling treatment within 20 minutes of arriving, and it may help protect your brain while you are unconscious.
GrazAges 18–79 - NCT05889507RecruitingPhase 3
Cooling treatment for newborns with mild brain injury
This Phase 3 study tests whether cooling a newborn’s body can help babies with mild brain injury after a difficult birth. It aims to see if cooling improves brain-related outcomes compared with standard care.
NaplesAges 1 hour–6 hours - NCT05836610RecruitingPhase 4
Testing hydrocortisone dosing during newborn cooling
This Phase 4 trial studies the best way to give hydrocortisone (a steroid medicine) to newborns who are being cooled for a specific kind of birth-related lack of oxygen. It’s for babies who have low blood pressure during cooling, aiming to improve their stability while they receive standard treatment.
Budapest, Pest CountyAges Up to 3 days - NCT05778188RecruitingPhase 2
RLS-0071 for newborns with moderate or severe HIE
This trial studies whether RLS-0071 is safe and can help some newborns with moderate or severe hypoxic-ischemic encephalopathy (HIE), a brain injury caused by low oxygen around birth. Babies in the study also receive standard whole-body cooling (therapeutic hypothermia), and the researchers will watch for side effects and early signs of benefit.
Little Rock, ArkansasAges Up to 10 hours - NCT02793999Recruiting
Near-infrared monitoring to guide cooling in newborns
This study tests a special, non-invasive sensor (near-infrared light) to help doctors choose the best cooling treatment for some newborns after brain injury. It may improve how well cooling works and how safely it’s managed in the first week of life.
Boston, MassachusettsAges Up to 2 years - NCT04976712Recruiting
Check body temperature in adults after out-of-hospital arrest
This trial measures core body temperature in adults who were taken to the hospital after an out-of-hospital cardiac arrest. It aims to understand temperature patterns during care, which may help guide how patients are treated after the event.
BruneckAges 18 years+ - NCT04621279Recruiting
Cooling treatment study for babies with mild brain injury
This study compares different approaches to “cooling” treatment in newborns with mild hypoxic-ischemic encephalopathy (mild brain injury from not enough oxygen around birth). The goal is to see which approach works best and is safest for babies like yours.
Dallas, TexasAges 8 months+ - NCT02991690Recruiting
Cooling treatment for acute neck spinal cord injury
This trial tests whether lowering your body temperature soon after a neck spinal cord injury can improve recovery. It is meant for certain types of spinal cord damage and looks at patients who can safely start cooling within 24 hours.
Phoenix, ArizonaAges 18–70 - NCT02621944RecruitingEarly Phase 1
Melatonin for newborns with brain injury after oxygen problems
This early study tests whether giving melatonin to newborns with hypoxic-ischemic encephalopathy (brain injury from not enough oxygen around birth) can help protect the brain while they are cooled (therapeutic hypothermia). It may be most relevant if your baby shows early brain-injury signs and meets specific blood test and birth-history timing criteria.
Gainesville, FloridaAges Up to 6 hours
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Common questions
- Are there clinical trials for hypothermia?
- Yes. Clin2 currently lists 48 recruiting hypothermia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hypothermia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hypothermia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.