Clinical trials
Vaginal Microbiome clinical trials
Below are recruiting vaginal microbiome clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06912126Recruiting
The Maggie Project: Exploring vaginal microbiome origins and heredity
This study looks at how the vaginal microbiome is passed between family members or close contacts. If you are a Belgian woman in good health who can join with her mother and another person, you may help researchers understand what shapes this bacteria community.
AntwerpAges 10 years+ - NCT05505110RecruitingEarly Phase 1
Vaginal seeding to change a baby’s early gut microbes
This early-phase study looks at whether swabbing a mother’s vagina during a planned C-section (“vaginal seeding”) can help shape a newborn’s early respiratory and gut microbes. The goal is to see if this approach is safe and may influence early-life breathing health.
Nashville, TennesseeAges 18–40 - NCT03298334RecruitingPhase 1/Phase 2
Testing vaginal bacteria transfer to newborns after C-section
This study looks at whether they can safely place “healthy vaginal bacteria” from the mother into the newborn after a scheduled C-section, and whether it improves the baby’s health. It only enrolls certain mothers and babies based on infection testing and other health factors.
Falls Church, VirginiaAges birth–50 years - NCT07109713Recruiting
Cranberry products and women's health study
This trial tests if cranberry-based products can affect the natural balance of bacteria in the female body. It aims to understand how diet might support women's health.
Chicago, IllinoisAges 18–45 - NCT05510622Recruiting
Uterine microbiome study for recurrent pregnancy loss
This study looks at the normal bacteria and other microorganisms in the uterus to better understand recurrent pregnancy loss. You may be in a group with recurrent pregnancy loss or in a comparison group without pregnancy loss, and you’ll be asked to meet specific health and timing rules for samples.
Ho Chi Minh City, Ho Chi Minh CityAges 18–38 - NCT05405270Recruiting
Testing how well imiquimod works for abnormal cervix cell changes
This study looks for ways to predict who will respond to imiquimod cream for precancerous cervical cell changes (CIN2 or CIN3). Results may help doctors choose the best treatment approach and better plan follow-up.
BredaAges 18 years+ - NCT06643065Recruiting
Vaginal microbiome and pregnancy with genetically normal embryos
This study looks at how the natural community of germs (microbiome) in the vagina might affect the chance of becoming pregnant after transferring a genetically normal embryo. It could help doctors understand if the vaginal environment plays a role in IVF success.
BarcelonaAges 18–50 - NCT02898818Recruiting
Study of interactions between vaginal and oral microbiomes
This study looks at how the bacteria (microbes) in the vagina and in the mouth may affect each other. It may help improve understanding of vaginal health and related conditions.
Turku, TurkuAges 18 years+ - NCT05966649Recruiting
Synbiotics for preventing preterm birth in higher-risk pregnancies
This trial tests whether taking synbiotics (a mix of “good” probiotics and “food” for them) can help lower the chance of going into labor too early. It’s for pregnant people with certain risk factors for preterm birth, and it compares outcomes while you follow the study plan.
Edegem, AntwerpenAges 18 years+ - NCT04046900RecruitingPhase 1/Phase 2
Fecal-style transplant of vaginal microbiome for recurring BV
This trial tests whether transplanting “good bacteria” into the vagina can treat recurrent bacterial vaginosis (BV). It may help restore a healthier vaginal bacterial balance and reduce BV episodes.
Boston, MassachusettsAges 18–50 - NCT06646185Recruiting
Improving menstrual and vaginal health for women
This study looks at menstrual and vaginal health in women aged 18 to 35. It aims to understand normal cycles and find ways to improve health for all.
Yaoundé, YaoundéAges 18–35 - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT05640700Recruiting
Study of vaginal microbiome in HPV-related early cell changes
This study looks at the vaginal “microbiome” (the normal germs and bacteria in the vagina) in people who have had abnormal Pap smear or colposcopy results related to HPV. It may help doctors understand what to monitor and how to better identify early, pre-cancer changes in the cervix.
JerusalemAges 25–70 - NCT05706922Recruiting
Study gut and vaginal bacteria in PCOS women
This study looks at differences in gut and vaginal bacteria in people with PCOS (a hormone-related condition). You may help researchers understand what bacterial patterns are linked to PCOS and why that might matter for symptoms.
Rotterdam, South HollandAges 18–45 - NCT06649201Recruiting
Study of vaginal health after stem cell transplant
This study looks at how stem cell transplants affect the vagina, especially if you develop a condition called graft-versus-host disease (GVHD). Researchers will examine the vagina and test its natural germs (microbiome) to better understand and possibly improve treatment.
Cleveland, OhioAges 18–70 - NCT06356012RecruitingPhase 4
Imiquimod for high-risk HPV cervical lesions
This trial tests if imiquimod cream can help clear high-grade cervical lesions caused by high-risk HPV. It may be an option for people who want to avoid surgery.
BarretosAges 25–45 - NCT06709976Enrolling by invitation
Fertility test and IVF study
This study looks at whether a special test called ReceptIVFity, which checks the health of the vagina, can help improve pregnancy rates in women undergoing IVF or ICSI. If you are planning IVF or ICSI and are of European origin, you might be able to join.
Rotterdam, South HollandAges 18–42 - NCT05753813RecruitingEarly Phase 1
Study lactic acid gel to change vaginal germs
This early study tests whether placing a lactic acid gel inside the vagina can change the vaginal “microbiome,” the mix of germs, to help reduce repeat BV or yeast infections. You may join if you’ve had at least two recent episodes that needed treatment.
Honolulu, HawaiiAges 18–54 - NCT06051201Recruiting
ReceptIVFity test for IVF success prediction
This trial studies a vaginal swab test called ReceptIVFity that looks at the bacteria in your vagina to see if it can help predict how well IVF will work. You can join if you're about to start your first IVF cycle, are not on hormonal birth control or antibiotics, and your IVF is not for emergency reasons.
RotterdamAges 18–42 - NCT06662747Recruiting
Vaginal microbiome study for African women
This study is looking at the bacteria living in the vagina to understand what makes a healthy microbiome in African women. You will provide self-collected swabs and attend visits to help researchers learn more about vaginal health.
Kisumu, Kisumu CountyAges 18–40 - NCT07144826RecruitingEarly Phase 1
Probiotic for Gut and Vaginal Health in Ovarian Cancer Chemotherapy
This trial tests whether taking a probiotic supplement can help balance the bacteria in your gut and vagina while you undergo chemotherapy for advanced ovarian cancer. It aims to see if this could improve your treatment experience or outcomes.
Columbus, OhioAges 18 years+ - NCT06264219RecruitingPhase 1
Restoring gut bacteria after C-section birth
This trial tests whether giving a small dose of the mother's vaginal bacteria to babies born by C-section can help restore their gut microbiome. It may reduce the risk of allergies and other immune-related conditions later in life.
Gentofte Municipality, CopenhagenAges 18 years+ - NCT07194551Recruiting
Checking uterine cancer risk in Lynch syndrome with home sampling
This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.
Vancouver, British ColumbiaAges 30 years+ - NCT05127252Recruiting
Study how gut bacteria may affect time to pregnancy
This study looks at whether differences in the gut (microbiome) are linked to how long it takes to get pregnant and pregnancy outcomes. It may help researchers understand who might benefit from future microbiome-focused approaches.
Stockholm, HuddingeAges 18–40
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Common questions
- Are there clinical trials for vaginal microbiome?
- Yes. Clin2 currently lists 27 recruiting vaginal microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaginal microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaginal microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.