Clinical trials
Immunization clinical trials
Below are recruiting immunization clinical trials, each written for real people, not researchers. We’re tracking 1,069 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05108818RecruitingPhase 4
Study immune responses after an flu shot in healthy adults
This study gives you a flu vaccine and measures how your immune system reacts, including both “blood immunity” and “cell immunity.” It’s for healthy adults and mainly aims to better understand how well flu vaccines work in people without major health issues.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05134779Recruiting
Study aims to tailor cancer treatment to your biology
This study looks at how genes, the cancer environment, and your immune system interact to develop treatments that work better for people with breast cancer. It may help researchers learn why some treatments work for certain people and not others.
New York, New YorkAges 18–90 - NCT05141474RecruitingEarly Phase 1
Personalized immune cell treatment for advanced cancers after failed therapy
This trial tests a personalized therapy made from your own immune cells (TIL) picked to match your tumor’s “neoantigens,” plus standard immune-boosting medicine (including IL-2). It’s for people with advanced epithelial or immune “resistant” solid tumors whose cancer has continued growing despite available treatments.
BarcelonaAges 18 years+ - NCT05152238Recruiting
ITP registry and optional blood sample collection study
This study helps doctors better understand immune thrombocytopenia (ITP) by collecting basic patient information and, if you agree, storing blood samples. It may help future care decisions and research for people with ITP.
AachenAges 18 years+ - NCT05191381Recruiting
Immune treatment using exosome therapy for severe COVID-19
This trial tests whether immune-supporting treatment made from exosomes can help people with critically severe COVID-19 and lung damage. If you qualify, you may receive this therapy as part of the study to see if it improves outcomes.
UlmAges 18–90 - NCT05205200RecruitingPhase 2
Immune therapy for HR-positive, HER2-negative metastatic breast cancer
This Phase 2 trial studies an immune-based treatment for women with HR-positive and HER2-negative breast cancer that has spread or returned and can’t be cured with local treatment alone. The goal is to see whether the therapy can shrink tumors and improve disease control with acceptable safety.
ShanghaiAges 18–75 - NCT05209568Recruiting
Study of immune reactions after eating gluten
This study looks at how your immune system responds when you eat gluten, including for people with celiac disease. You may be asked to follow a gluten-free diet first and then safely reintroduce gluten so researchers can measure immune changes.
Aurora, ColoradoAges 2–101 - NCT05215327RecruitingPhase 2
Higher-dose flu vaccine vs standard dose after lung transplant
This trial tests whether a higher dose of flu vaccine works better than the standard dose for people who have had a lung transplant. It may help improve protection against seasonal flu while monitoring safety.
Nashville, TennesseeAges 16 years+ - NCT05262673RecruitingPhase 1
Combination immunotherapy for B-cell acute lymphoblastic leukemia
This trial tests a combination of immune cells (CTL and DC vaccines) to target B-ALL. It may help patients with high levels of leukemia cells who have not responded to other treatments.
Shenzhen, GuangdongAges 6 months–65 years - NCT05266092Recruiting
Study kidney disease immune system activity in dialysis patients
This study looks at how the body’s defense systems (immune system and related signals) behave in people with chronic kidney disease. It may help doctors understand what is driving inflammation and related complications in dialysis patients.
OdenseAges 18 years+ - NCT05271669Recruiting
Study of COVID-19 immunity over time
This study looks at how people’s immune protection after COVID-19 may change over time. It aims to better understand immunity, which could help doctors plan future care and prevention.
Hong Kong, HONG KONGAges Any age - NCT05273138Recruiting
Study of skin immune and support cells in systemic sclerosis
This study looks at skin cells and immune cells in people with systemic sclerosis to better understand what drives the disease. Your participation may help researchers learn how the immune system and skin support cells change over time.
LilleAges 18 years+ - NCT05277753RecruitingPhase 1
Personalized immune therapy for T-ALL
This trial tests a combination of personalized immune therapies (using your own cells to fight cancer) for T-cell acute lymphoblastic leukemia. It targets specific markers on your leukemia cells and uses a bone marrow sample to create a custom treatment.
Shenzhen, GuangdongAges 6 months–65 years - NCT05283226RecruitingPhase 2
Oral anti-cancer pill plus paclitaxel after immunotherapy failure
This Phase 2 trial studies an oral study drug (NRC-2694-A) given with paclitaxel to treat head and neck squamous cell cancer that has come back or spread after immunotherapy. It tests whether this combination is safer and works better than expected for people whose cancer progressed on immune checkpoint inhibitors.
Fullerton, CaliforniaAges 18 years+ - NCT05284539RecruitingPhase 2
Chemo plus immunotherapy for mutated advanced lung cancer
This trial studies whether combining platinum chemotherapy with immune “checkpoint” medicine works better for people with stage IV lung cancer that has EGFR, ALK, or ROS1 mutations. It focuses on tumors that have grown again after first-line treatment.
Changsha, HunanAges 18 years+ - NCT05312255Recruiting
Non-drug help to improve quality of life in myeloma
This study tests non-chemotherapy supports meant to improve quality of life and immune health for people with multiple myeloma (or related conditions). Depending on the group, it may involve activities, nutrition, and/or a medication like a beta blocker.
Buffalo, New YorkAges 18 years+ - NCT05324475Recruiting
Nutritional supplement to support immunity and energy in older adults
This trial tests whether a safe nutrition supplement can help older adults with malnutrition maintain immune function and energy (mitochondrial function). It may support recovery during rehabilitation, but you must meet specific nutrition and health criteria.
Lausanne, SwitzerlandAges 75 years+ - NCT05327686RecruitingPhase 2
Adding focused radiation to immunotherapy for kidney cancer
This Phase 2 trial studies whether adding focused, high-precision radiation to immunotherapy helps people with advanced kidney cancer (that cannot be removed by surgery or has spread). It aims to improve cancer control by combining two treatment approaches.
Birmingham, AlabamaAges 18 years+ - NCT05328856Recruiting
Vital shower study to improve well-being and body regulation
This trial studies whether a special “vital shower” can improve quality of life, immune-related measures, heart/blood-pressure regulation, and overall well-being. You may be a fit if you’re generally healthy enough and can safely use the shower setup during the study.
Berlin, State of BerlinAges 18–70 - NCT05331066Recruiting
Tracking side effects from immunotherapy using multiple tests
This study looks at how side effects happen in people receiving immune checkpoint inhibitor immunotherapy for solid cancers. It uses multiple types of tests to better understand these toxicities and may help improve safety and care in the future.
Chelsea, LondonAges 18 years+ - NCT05332925Recruiting
Tumor samples grown in dishes to predict immunotherapy response
This study takes small biopsy samples of your lung cancer and grows them in a dish to predict how well immunotherapy will work. If you qualify, you’ll receive standard immunotherapy (anti-PD-1/L1, with or without anti-CTLA-4), and the results from the dish-grown tumors will be compared to your real-world response.
Fairway, KansasAges 18–110 - NCT05338294Recruiting
Tested surgery to help immune function in cirrhosis
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Yangzhou, JiangsuAges 18 years+ - NCT05339529Recruiting
Thymosin A1 to help protect organs after emergency aortic surgery
This study looks at whether thymosin A1 can reduce immune-related problems and organ injury after emergency surgery for an acute aortic condition. If you qualify, you may receive thymosin A1 as part of the treatment plan to see if it improves recovery.
Bengbu, AnhuiAges 18–90 - NCT05359796Recruiting
Study of long-term type 1 diabetes symptoms and characteristics
This study looks at what day-to-day health and medical features are like in people who have had type 1 diabetes for many years. It may help researchers better understand long-term needs in type 1 diabetes and guide future care.
Changsha, HunanAges Any age
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Common questions
- Are there clinical trials for immunization?
- Yes. Clin2 currently lists 1,069 recruiting immunization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.