Clinical trials
Immunization clinical trials
Below are recruiting immunization clinical trials, each written for real people, not researchers. We’re tracking 1,061 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00006150Recruiting
Understanding Hyper-IgE Syndrome: Natural History and Genetics
This study follows people with or suspected Hyper-IgE syndrome (a rare immune disorder causing repeated infections and skin problems) to understand how the condition develops, how best to manage it, and which genes are involved. Researchers also welcome healthy relatives of patients to help identify genetic patterns.
Bethesda, MarylandAges 1 month–120 years - NCT01011712Recruiting
Study immune causes of severe viral infections
This study looks at why some people have severe or unusual viral infections, even when they do not have a known immune problem. It collects blood and tissue samples to better understand possible inherited immune issues and may help future diagnosis and treatment.
Bethesda, MarylandAges 2–100 - NCT01568697Recruiting
Studying gum disease in people with immune and genetic differences
This study looks at how mouth bacteria and the immune system may work together to cause gum disease (periodontitis), especially in people with certain genetic immune problems. It may help researchers understand what drives severe gum disease and how to better monitor or treat it in the future.
Bethesda, MarylandAges 7–100 - NCT01720836RecruitingPhase 1/Phase 2
MUC1 peptide vaccine study for non-small cell lung cancer
This trial tests a vaccine made from a lung-cancer target (MUC1) to help your immune system recognize and fight the cancer. It is designed to measure immune response and safety, and it may help some people develop a stronger anti-cancer immune reaction.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT00920972RecruitingPhase 1/Phase 2
Bone marrow transplant prep for children with non-cancer blood disorders
This early-stage study tests a specific chemotherapy “conditioning” regimen to prepare the body for a bone marrow transplant in children with certain non-cancer blood or immune conditions. It may help the transplant work better, but it also carries risks from the chemotherapy and transplant process.
Phoenix, ArizonaAges Up to 20 years - NCT01351545Recruiting
Cryopreserved cord blood access program for transplant patients
This trial studies an organized way to obtain and distribute unlicensed (not FDA-approved for general use) stored cord blood units that have been frozen and kept. It may help people who need a cord blood transplant but don’t fit the “licensed cord blood only” options.
Birmingham, AlabamaAges Any age - NCT01397669Recruiting
Study immune differences in HIV and HIV-negative adults
This research compares the immune system in the gut lining, spinal fluid, lymph nodes, and blood between people living with HIV and people not living with HIV. Results may help scientists understand how immunity works and how it differs with HIV.
Bangkok, BangkokAges 18–50 - NCT02129543Recruiting
Study immune recovery after stem cell or T-cell treatment
This study looks at how your immune system “rebuilds” after certain cell-based cancer treatments or stem cell transplants. It may help researchers better understand why immune recovery differs between people and how to improve protection against infections.
Miami, FloridaAges 18–75 - NCT02147405Recruiting
PET scans and lymph node checks for HIV immune rebound
This study looks at people with HIV who either have not started HIV medicines yet or who recently started/changed them and may develop immune rebound (IRIS). It uses blood tests and optional PET/CT scans and lymph node biopsies to understand what’s happening in the body and to guide care.
Bethesda, MarylandAges 18–100 - NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT02735824Recruiting
Genetic study of immune problems in children
This study looks for new genetic causes of immune system conditions that can run in families. If you join, researchers will collect health information (and usually samples) from children with immune concerns and from close relatives for comparison.
Zurich, Canton of ZurichAges Any age - NCT02526901Recruiting
Pregnancy cohort study for women in Guangzhou
This study follows pregnant women from early pregnancy to learn about pregnancy and child health. You may be asked to share health information so researchers can better understand outcomes for babies born in Guangzhou.
Guangzhou, GuangdongAges Any age - NCT02579967RecruitingPhase 2
Stem cell transplant for primary immune system disorders
This study tests whether an allogeneic stem cell (bone marrow) transplant can correct an inherited immune problem in people with severe primary immunodeficiencies. It may help reduce life-threatening infections and improve quality of life, depending on your overall health and donor match.
Bethesda, MarylandAges 4–75 - NCT02869048Recruiting
Study blood and immune signals in ALS and healthy controls
This trial studies the “innate immune system” (your body’s first-line immune response) in people with ALS and in comparison groups. It may help researchers understand what drives ALS and how immune changes could relate to symptoms.
AarhusAges 18 years+ - NCT03159364RecruitingPhase 1/Phase 2
Immune cells for viral infections after transplant
This trial tests whether specially grown immune cells (T cells) can fight common viruses like CMV, EBV, or BK virus in people with weakened immune systems, such as after a stem cell or organ transplant. It may help when standard medicines don't work or can't be used.
Shenzhen, GuangdongAges 6 months–80 years - NCT03184753RecruitingPhase 1/Phase 2
Modified immune T cells for high-risk ovarian cancer
This early-phase study tests modified immune T cells to treat high-risk stage III–IV ovarian cancer. It aims to see whether the treatment can be given safely and whether it can help control the cancer.
Shenzhen, GuangdongAges 18–65 - NCT03125577RecruitingPhase 1/Phase 2
CAR-T treatment for blood cancers with certain markers
This trial tests a combination CAR-T cell therapy for blood cancers that show specific markers (like CD19 or CD20) on tumor cells. It may help by using the patient’s immune cells to better find and attack the cancer.
Shenzhen, GuangdongAges 6 months–75 years - NCT03240328RecruitingPhase 1
CAR-T therapy study for rebuilding HIV immune defenses
This early-stage study tests whether CAR-T cells can help rebuild the immune system’s ability to fight HIV. You may be a candidate if your HIV is well controlled on standard treatment and you don’t have certain serious infections or organ problems.
Guangzhou, GuangdongAges 18–60 - NCT03323112Recruiting
Studying immune responses to seasonal flu shots in health workers
This study looks at how your immune system (your body’s infection-fighting system) responds after you get the seasonal flu vaccine. It may help researchers understand what the vaccine triggers in people working in healthcare and labs.
HelsinkiAges 18–64 - NCT03222674RecruitingPhase 1/Phase 2
CAR T treatment for acute myeloid leukemia in children and adults
This trial tests a lab-made immune cell treatment (CAR T cells) that targets specific markers on acute myeloid leukemia cells. It aims to control the leukemia, but it also involves close monitoring because it is an early-phase study.
Shenzhen, GuangdongAges 2–75 - NCT03217032RecruitingPhase 1
Gene therapy trial for hemophilia A using FVIII
This Phase 1 study tests a gene therapy designed to help the body make factor VIII (FVIII), which is missing in hemophilia A. It may help reduce bleeding and the need for FVIII infusions, but it is an early-safety trial.
Shenzhen, GuangdongAges 2–65 - NCT03217617RecruitingPhase 1/Phase 2
Gene therapy by vein for SCID-X1 immune deficiency
This trial tests an experimental gene therapy given through a vein to help children with SCID-X1 make needed immune cells. It may help reduce severe infections when standard options like a matched donor are not available.
Shenzhen, GuangdongAges 1 month–1 year - NCT03351868Recruiting
Gene therapy for Fanconi anemia type A
This trial tests a new gene therapy for people with Fanconi anemia type A. A modified virus carries a working copy of the FANCA gene into your blood stem cells, which may help your bone marrow produce healthy blood cells.
Shenzhen, GuangdongAges 2–20 - NCT07464314RecruitingPhase 1
Testing a combined flu and COVID-19 mRNA vaccine in older adults
This trial is testing whether a new mRNA vaccine that targets both seasonal flu and COVID-19 is safe and creates a strong immune response. It may offer an easier way to protect against two illnesses with one shot.
Anniston, AlabamaAges 65–85
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Common questions
- Are there clinical trials for immunization?
- Yes. Clin2 currently lists 1,061 recruiting immunization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.