Clinical trials
Immunology clinical trials
Below are recruiting immunology clinical trials, each written for real people, not researchers. We’re tracking 135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07208058RecruitingPhase 3
Testing plonmarlimab for blood cell overactivation in people with rheumatic disease
This trial tests a new drug called plonmarlimab for people with a rheumatic (joint or immune) disease who also have a dangerous overreaction of their immune system called HLH (or MAS). The goal is to see if the drug can help when high-dose steroids have not worked or are not an option.
Beijing, Beijing MunicipalityAges 16–80 - NCT07637877RecruitingPhase 2
New Treatments for HIV Patients With Low Immune Cell Counts
This study tests targeted therapies to help HIV patients whose immune systems haven't fully recovered despite years of successful HIV medication. You may qualify if your CD4 count (a measure of immune health) stays low even though your viral load is undetectable.
Beijing, Beijing MunicipalityAges 18–60 - NCT04448951Recruiting
Study of immune response in early sepsis or septic shock
This trial looks at how the immune system behaves in the first day after septic shock begins. It may help researchers find better ways to support the body’s immune balance during sepsis, but you must be enrolled very quickly.
Pilsen, Česká RepublikaAges 18 years+ - NCT04784364Recruiting
Study of immune treatments at Mount Sinai
This study follows people who are receiving immune-related medications (called biologics or immune modulators) at Mount Sinai. It aims to better understand how these treatments affect the immune system and health over time, which may help improve future care.
New York, New YorkAges 12 years+ - NCT05209776Recruiting
Studying heart inflammation patterns in specific heart rhythm conditions
This study compares inflammation-related signals in people with arrhythmogenic right ventricular cardiomyopathy versus people having certain heart procedures for non-cancer, non-inflammatory reasons. It may help researchers better understand what drives abnormal heart rhythms in this condition.
ToulouseAges 18–99 - NCT05525507RecruitingPhase 1
Test early immune-tolerance treatment for matched kidney transplant patients
This Phase 1 study tests a treatment plan given after a kidney transplant to help the immune system stay calm and reduce the risk of rejection. Participants must have a well-functioning kidney transplant from a closely matched living donor and meet health and safety requirements.
Los Angeles, CaliforniaAges 18 years+ - NCT06385288Recruiting
Blood and tissue study in high-risk sarcoma
This study collects blood and tissue samples from people with high-risk soft tissue sarcoma before their surgery. The goal is to learn how the immune system responds to pre-surgery treatments like radiation and hyperthermia (heat therapy).
Tübingen, Baden-WurttembergAges 18 years+ - NCT07291206Recruiting
Arbovirus T cell response study
This trial uses a blood test to look at how your immune system fights certain viruses spread by insects (like mosquitoes). Your participation could help doctors better understand and diagnose these infections.
Pavia, LombardyAges 18 years+ - NCT07427186Recruiting
Studying how immunotherapy affects the immune system in early-stage cancer
This trial looks at how your immune system responds to immunotherapy given before surgery for early-stage solid tumors (like lung, head and neck, melanoma, or bladder cancer). The goal is to understand why some people respond better, so doctors can improve treatment for future patients.
ToulouseAges 18 years+ - NCT02232191RecruitingPhase 2
Pneumonia vaccine immune response study after spleen injury
This trial studies how your immune system responds to a pneumonia (pneumococcal) vaccine after a spleen injury. It may help doctors better predict and improve protection in people recovering from splenic trauma.
Sacramento, CaliforniaAges 18–65 - NCT07579741RecruitingPhase 1/Phase 2
Testing JL18008 for HIV Patients Not Recovering Immune Cells
This study tests an experimental drug called JL18008 in people with HIV who have been on stable HIV medications for years but whose immune systems (CD4 cells) haven't recovered as expected. The drug may help boost immune function in these patients.
Beijing, Beijing MunicipalityAges 18–65 - NCT06814444Recruiting
Immune system study in acute leukemia
This study is looking at blood and bone marrow samples from people with acute leukemia to understand how the immune system reacts to the disease and treatment. The goal is to find better ways to treat leukemia.
Bologna, BolognaAges 18 years+ - NCT06235892RecruitingPhase 3
Lowering Tacrolimus for Low-Risk Kidney Transplant Patients
This trial tests whether safely lowering the dose of tacrolimus—an anti-rejection drug—can still protect a kidney transplant one year after surgery. It's for first-time transplant recipients with low immune risk.
NantesAges 18 years+ - NCT06025240Recruiting
Better antibody monitoring after kidney transplant
This study tests a new way to monitor harmful antibodies after a kidney transplant. It may help prevent transplant rejection over time.
Liverpool, MerseysideAges 18 years+ - NCT05549167RecruitingPhase 3
Sirolimus for children with juvenile nasal blood tumors
This trial tests whether sirolimus can shrink or control juvenile nasopharyngeal angiofibroma in children and teens, and checks its safety. It may help families who cannot rely only on surgery, especially for larger or hard-to-treat tumors.
MoscowAges 7–18 - NCT04824040Enrolling by invitation
Study of immune, muscle, and genetic features in LGMD 2B
This study looks at immune function, muscle appearance, and genetic information in people with limb-girdle muscular dystrophy type 2B. It may help researchers understand the condition better, which can support future treatments.
MoscowAges 18–85 - NCT04335773Recruiting
Study of COVID-19 in hospitalized children
This study looks at children (ages 0 to 18) who are in the hospital with suspected COVID-19. It aims to understand what factors affect outcomes and how the immune system responds.
LørenskogAges Up to 18 years - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT06356012RecruitingPhase 4
Imiquimod for high-risk HPV cervical lesions
This trial tests if imiquimod cream can help clear high-grade cervical lesions caused by high-risk HPV. It may be an option for people who want to avoid surgery.
BarretosAges 25–45 - NCT07456358Recruiting
Immune attack targets in brain disease
This study looks at the immune system's role in neurological problems caused by cancer immunotherapy or autoimmune diseases. Researchers will collect spinal fluid to find out which immune targets are involved, which may help improve diagnosis and treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT06759831Recruiting
Clinical outcomes of living and deceased donor kidney transplants
This study looks at how well kidney transplants work from both living and deceased donors. It may help doctors better understand long-term outcomes for people who get a new kidney.
Bologna, BOAges 18 years+ - NCT07477925Recruiting
Studying immune markers for CMV in pregnancy
This study looks at how the immune system responds to a first-time cytomegalovirus (CMV) infection during pregnancy. The goal is to find better ways to predict if the virus will pass to the baby.
Pavia, LombardyAges 18 years+ - NCT05825183Recruiting
Ultrasound-guided vacuum procedure study after early pregnancy loss
This trial studies a medicine-product made from conception tissue (from an ultrasound-guided manual vacuum aspiration procedure) for people with an early miscarriage or termination. It may help researchers understand whether this approach is safe and potentially beneficial for recovery, but eligibility depends on specific medical and procedural factors.
Hong KongAges 18 years+ - NCT05132348Recruiting
Studying immune markers in people with osteoporosis
This study looks at immune system “fingerprints” (immunophenotyping) in adults who have been diagnosed with osteoporosis. It may help researchers understand what drives osteoporosis and could guide better future treatments.
Bonn, Northrhine WestfaliaAges 18 years+
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Common questions
- Are there clinical trials for immunology?
- Yes. Clin2 currently lists 135 recruiting immunology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a immunology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a immunology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.