Clinical trials
Infectious Disease clinical trials
Below are recruiting infectious disease clinical trials, each written for real people, not researchers. We’re tracking 254 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06680843Recruiting
Immune signatures from animal virus exposure in Cambodia
This study aims to understand how people's immune systems respond to viruses that spread from animals to humans (zoonotic viruses). If you have had recent contact with potentially infected animals in Cambodia, your participation can help researchers find ways to detect and prevent future outbreaks.
BattambangAges 18–65 - NCT06071767RecruitingPhase 1/Phase 2
Immune therapy trial for early-treated HIV
This study tests whether a combination of three immune therapies can help control HIV without daily medication. You may qualify if you started HIV treatment very early and have had a suppressed viral load for at least a year.
San Diego, CaliforniaAges 18 years+ - NCT06280950RecruitingPhase 2
Reducing immune-suppressing drugs after liver transplant with everolimus
This study tests if adding everolimus can allow liver transplant recipients to safely reduce their usual immune-suppressing medicines. It aims to protect kidney function while preventing organ rejection.
Phoenix, ArizonaAges 18 years+ - NCT06033196RecruitingPhase 2
Tocilizumab to prevent lung transplant rejection
This trial tests a drug called tocilizumab (brand name Actemra) to see if it helps prevent rejection after lung transplantation. Tocilizumab targets part of the immune system that may otherwise attack the new lungs.
Phoenix, ArizonaAges 12–75 - NCT06055608RecruitingPhase 2
Improving kidney transplant outcomes in teens and young adults
This trial tests a new approach to help teenagers and young adults keep their first kidney transplant working well. It looks at how to improve long-term success by carefully managing the immune system around the time of transplant.
Birmingham, AlabamaAges 13–20 - NCT07271381Recruiting
Testing how allergens and everyday toxins affect your body
This study looks at how common allergens and everyday toxins from things like cleaning products affect your skin, gut, and airways. It may help find ways to prevent or manage allergies and related health issues.
Bethesda, MarylandAges 18–80 - NCT00767312Enrolling by invitation
Study how HIV multiplies during HIV drug treatment
This study looks at how HIV continues to multiply (or stays suppressed) while you are taking antiretroviral therapy, using blood samples. It may help researchers better understand what HIV is doing during treatment and why some people experience changes like viral rebound.
Bethesda, MarylandAges 18–99 - NCT05719441RecruitingPhase 2
Antibodies plus early HIV treatment to try for HIV remission
This study tests whether giving special HIV-fighting antibodies along with starting standard HIV medicine soon after infection can help you reach “HIV remission.” It may reduce or delay the return of detectable virus, but you must be willing to follow close monitoring and specific study steps.
Birmingham, AlabamaAges 18–70 - NCT07626606Recruiting
Gut Health and Rotavirus Vaccine Response in Adults
This study examines how the health of your digestive system affects how well your body responds to an oral rotavirus vaccine (a vaccine given by mouth to protect against rotavirus infection). You'll have two endoscopy procedures—a camera test to look inside your digestive tract—and provide samples to help researchers understand this connection.
Lusaka, Lusaka ProvinceAges 18–50 - NCT05917522RecruitingPhase 2
Biomarker-guided changes to anti-rejection medicines after kidney transplant
This Phase 2 study looks at whether blood test “biomarkers” can guide safely changing anti-rejection medicines after an ABO-compatible kidney transplant. It may help some people reduce certain medicines while keeping the new kidney protected from rejection.
Birmingham, AlabamaAges 18–70 - NCT07390474RecruitingPhase 1
HIV vaccine safety and immune response study for healthy adults
This study tests two experimental mRNA-based HIV vaccines to see if they are safe and create an immune response. It is for healthy adults aged 18 to 55 who do not have HIV.
Atlanta, GeorgiaAges 18–55 - NCT06517693RecruitingPhase 1
HIV antibody safety study for newborns at risk
This study tests whether giving a combination of two lab-made antibodies (PGT121.414.LS and VRC07-523LS) to newborns exposed to HIV during pregnancy is safe and how the body processes them. It may help protect infants from getting HIV after birth.
Los Angeles, CaliforniaAges Up to 3 days - NCT00114647Recruiting
Blood draw to collect plasma or white blood cells for lab tests
This trial uses a special blood-removal procedure called apheresis to collect either plasma or white blood cells for laboratory research. It may help scientists understand infection or immune-related processes by providing specific blood components for study.
Bethesda, MarylandAges 18–100 - NCT07030075Recruiting
Flu and respiratory infection study in Lusaka
This study looks at flu-like symptoms and other respiratory infections in adults in Lusaka, Zambia. It aims to understand how these infections affect people with and without HIV, and may help improve care.
Lusaka, Lusaka ProvinceAges 18 years+ - NCT00044122Recruiting
Study of mast cell growth in people with mastocytosis
This study looks at what causes mast cells to grow too much in people with mastocytosis. It may help researchers find better ways to diagnose or treat this condition. You can take part in person or by telehealth.
Bethesda, MarylandAges 1 day–80 years - NCT06422338Recruiting
Fast test to predict infection risk in febrile children
This study is testing a new, fast test to better identify which young children with fever are at risk for serious illness. If your child is eligible, they will be part of a group that helps doctors decide how to treat febrile children more accurately.
Lambaréné, Moyen-Ogooué ProvinceAges 2 months–5 years - NCT07107516RecruitingPhase 1
Testing an oral cholera vaccine in healthy adults
This study tests an oral cholera vaccine called PanChol in healthy adults. The goal is to see if it's safe and how the body responds. It may help protect against cholera, a serious diarrheal illness.
Lusaka, Lusaka ProvinceAges 18–55 - NCT03610802Recruiting
Send blood samples to study genetic and immune differences
This study collects blood (and sometimes related samples) to learn how genes and the immune system work in people with primary immunodeficiency (PID) or in family members who may not have it. The goal is to improve understanding of rare immune conditions and help guide future care.
Bethesda, MarylandAges 1 day–99 years - NCT00067054Recruiting
Collecting blood and samples for research
This study collects blood and other samples from healthy volunteers, children, and people with infectious diseases to help advance research. If you join, you may donate blood, urine, or skin samples that will be stored and used in future studies.
Bethesda, MarylandAges 3 years+ - NCT04364503Enrolling by invitation
Study that analyzes de-identified patient samples and records
This trial checks how well patient samples and health records can be analyzed when names are removed (“de-identified”) and privacy rules are followed. You might be included if you agree in writing and your sample data can be used for this research and/or your doctor requests it.
Los Angeles, CaliforniaAges Any age - NCT01306084Recruiting
Study of viral infections in healthy and immune-compromised people
This trial studies how viruses affect the body, and how the immune system responds, in both healthy people and people with weakened immunity. It may include people who currently have a suspected or recent viral infection, close contacts, people around the time of a viral vaccine, and healthy adults used for comparison.
Bethesda, MarylandAges 6 months–120 years - NCT07069400Recruiting
Observational study of adults with acute infection
This study observes adults hospitalized with a new or recent infection (symptoms started within 30 days). The goal is to learn more about how infections affect people in the hospital, without testing any new drugs or treatments.
Tucson, ArizonaAges 18 years+ - NCT07347015Recruiting
Antibiotic prescribing support for Belgian GP clinics
This trial tests a decision-support tool that helps doctors in Belgian primary care prescribe antibiotics more wisely. If your practice uses a compatible electronic health record system, you may be able to join.
Leuven, Vlaams-BrabantAges Any age - NCT03298334RecruitingPhase 1/Phase 2
Testing vaginal bacteria transfer to newborns after C-section
This study looks at whether they can safely place “healthy vaginal bacteria” from the mother into the newborn after a scheduled C-section, and whether it improves the baby’s health. It only enrolls certain mothers and babies based on infection testing and other health factors.
Falls Church, VirginiaAges birth–50 years
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Common questions
- Are there clinical trials for infectious disease?
- Yes. Clin2 currently lists 254 recruiting infectious disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a infectious disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a infectious disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.