Clinical trials
Infectious Disease clinical trials
Below are recruiting infectious disease clinical trials, each written for real people, not researchers. We’re tracking 260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03394053Recruiting
Studying the causes of primary immunodeficiency disorders
This study looks at blood samples and genetic information from people with primary immunodeficiency (a condition where the immune system doesn't work properly), their relatives, and healthy volunteers. The goal is to learn more about what causes these disorders, which could help improve future treatments.
Washington D.C., District of ColumbiaAges 1 day–90 years - NCT02504853Recruiting
Study food allergy patterns and genetics over time
This study follows people with food allergy and some closely related or healthy people to learn how food allergy (and related conditions) develops over time. It may help researchers find causes and better ways to predict and treat food allergy.
Bethesda, MarylandAges 1 day–99 years - NCT00004317RecruitingPhase 4
Treating Congenital Toxoplasmosis With Three Medications
This study tests a combination of three medications (pyrimethamine, sulfadiazine, and leucovorin) to treat toxoplasmosis—a parasitic infection passed from mother to baby during pregnancy. The goal is to see if early treatment prevents serious complications in infected infants.
Chicago, IllinoisAges Any age - NCT04020536Recruiting
Real-world study for several infectious diseases
This study follows people with confirmed brucellosis, epidemic hemorrhagic fever, or kala-azar (visceral leishmaniasis) to understand how these infections behave in real life. It may help improve care by collecting evidence on diagnosis and treatment outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04526431Recruiting
Tacrolimus dose study in early kidney transplant patients
This study looks at how tacrolimus (a rejection-preventing medicine) should be dosed in the first days to years after a kidney transplant. It may help personalize dosing by comparing different patient groups, including using genetic testing.
Grenoble, Auvergne-Rhône-AlpesAges 18 years+ - NCT05139524Recruiting
Fever and bleeding illness study in East and Central Africa
This study looks at people with fever or unexplained bleeding in East and Central Africa to learn more about illnesses like Rift Valley fever. By joining, you can help doctors understand and better treat these conditions.
Goma, North KivuAges 2 years+ - NCT04471493Recruiting
Study of children’s common infections in a clinic program
This trial is for children under 16 who have one of several common infections seen in outpatient or clinic visits. It aims to better study and manage these illnesses using a specific clinical documentation software.
CréteilAges 1 day–16 years - NCT07778459Recruiting
Liver transplant study for people with HIV
This study tests whether it's safe and effective for people with HIV to receive a liver transplant from a donor who also has HIV. It aims to expand access to transplants for people with HIV.
Baltimore, MarylandAges 18 years+ - NCT06004739Recruiting
Antibiotics for older adults with delirium and abnormal urine tests
This trial tests whether giving antibiotics helps older adults in the hospital who have delirium (sudden confusion) and signs of bacteria in their urine but no clear urinary infection. It aims to see if treatment can improve confusion and avoid unnecessary antibiotics.
Chicago, IllinoisAges 60 years+ - NCT07757802RecruitingPhase 1
HIV vaccine nanoparticle and mRNA booster for healthy adults
This study tests a new HIV vaccine that uses tiny particles (nanoparticles) and an mRNA booster — similar to some COVID vaccines. The goal is to see if it is safe and helps your body fight HIV. It's for healthy adults who do not have HIV.
San Francisco, CaliforniaAges 18–55 - NCT05515770RecruitingPhase 3
Injectable PrEP shot for HIV prevention in higher-risk adults
This Phase 3 study tests whether an injectable HIV prevention medicine (cabotegravir) given before exposure can help prevent HIV in people at higher risk. You may join if you are HIV-negative and meet specific sexual health, medication, and health-testing requirements.
Rio de JaneiroAges 18–30 - NCT07706686RecruitingPhase 1
Dengue challenge study in people with prior infection
This study tests how the body responds to a mild, lab-made dengue virus in people who have had dengue before. It looks at how the immune system reacts to a second infection, which may help improve future vaccines and treatments.
Bethesda, MarylandAges 18–50 - NCT07626606Recruiting
Gut Health and Rotavirus Vaccine Response in Adults
This study examines how the health of your digestive system affects how well your body responds to an oral rotavirus vaccine (a vaccine given by mouth to protect against rotavirus infection). You'll have two endoscopy procedures—a camera test to look inside your digestive tract—and provide samples to help researchers understand this connection.
Lusaka, Lusaka ProvinceAges 18–50 - NCT07611435RecruitingPhase 2
Testing a Safe Control for Alpha-Gal Syndrome Food Challenges
This study helps researchers understand the best way to safely test whether people with alpha-gal syndrome (an allergy to red meat) can tolerate pork. You'll undergo a controlled food challenge with medical supervision and access to emergency medications.
Little Rock, ArkansasAges 12–50 - NCT07605520RecruitingEarly Phase 1
COVID-19 Booster Vaccine Study for Previously Vaccinated Adults
This study tests new COVID-19 booster vaccine candidates in healthy adults who previously received mRNA COVID-19 vaccines. Researchers will monitor safety and how well your immune system responds to help develop better COVID-19 protection.
CréteilAges 18–65 - NCT06711575Recruiting
Personalized antibiotics for spinal infections
This trial is studying how to personalize the dose of anti-infection drugs for people with spinal infections. The goal is to find the best treatment for each patient to improve outcomes and reduce side effects.
JinanAges Any age - NCT07569029RecruitingPhase 1
HIV vaccine with treatment break to boost immune response
This Phase 1 trial tests two new HIV vaccines (DV700P-RNA and DV701B1.1-RNA) combined with a monitored break from HIV medications in people with well-controlled HIV. The goal is to see if this approach safely strengthens the immune system's ability to fight HIV.
Birmingham, AlabamaAges 18–60 - NCT07559318Recruiting
Optimizing Antibiotic Choice for Urinary Tract Infections
This study helps doctors choose the best antibiotic for urinary tract infections (UTIs) by looking at urine culture results. You'll be treated as an outpatient (at home) and monitored to see if your antibiotic is working well.
MelunAges 18 years+ - NCT07549503RecruitingPhase 2
Liver Transplant Immune Changes Study
This research study tracks early signs of immune system changes in children who received a liver transplant 3–7 years ago and are doing well. By studying blood and liver samples, researchers hope to better understand how to prevent rejection and improve long-term transplant survival.
San Francisco, CaliforniaAges 3–13 - NCT05300035RecruitingPhase 2
HIV treatment add-on antibodies during early infection
This study tests whether adding two antibody medicines to standard HIV treatment helps people control HIV better after stopping treatment. It focuses on people with recently diagnosed (“primary”) HIV infection, aiming to improve long-term control after ART is interrupted.
BobignyAges 18–70 - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Decatur, GeorgiaAges 18–64 - NCT07447869RecruitingEarly Phase 1
Lymph Node Exam in Cat Allergy Treatment Study
This study looks at lymph nodes in the neck to understand how the body responds to cat allergy treatments. It may help researchers improve allergy shots or other therapies for people with cat allergies.
Boston, MassachusettsAges 18–45 - NCT05655702Recruiting
Drug use and infections study for tuberculosis control in Vietnam
This study looks at how injecting drug use is linked with infections, including tuberculosis, and aims to improve TB control. You may be asked to share information and provide tests related to recent drug use and injection sites.
HaiphongAges 18 years+ - NCT04166266Recruiting
Study of adults with hepatitis D and hepatitis B coinfection
This study follows adults who have ongoing hepatitis D infection along with hepatitis B. It aims to better understand this mixed infection and how these patients do over time.
AngersAges 18 years+
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Common questions
- Are there clinical trials for infectious disease?
- Yes. Clin2 currently lists 260 recruiting infectious disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a infectious disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a infectious disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.