Clinical trials
Infertile Females or Females With Ovarian Insufficiency clinical trials
Below are recruiting infertile females or females with ovarian insufficiency clinical trials, each written for real people, not researchers. We’re tracking 166 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06956287Recruiting
New sperm-wash device for infertility couples
This trial tests a new device that cleans sperm before it's used in intrauterine insemination (IUI), a common fertility treatment. It aims to see if this device improves sperm quality and pregnancy chances for couples struggling with infertility.
Taichung, Taichung CityAges 25–50 - NCT06742788Recruiting
Vagus nerve stimulation for IVF patients with anxiety or depression
This trial tests whether a gentle form of nerve stimulation (taVNS) can improve pregnancy rates in women undergoing IVF who also have mild-to-moderate anxiety or depression. It aims to see if this treatment is both helpful and practical for this group.
Xi'an, ShaanxiAges 20–40 - NCT06975683Recruiting
PRGF ovarian injection for low ovarian reserve
This study tests a special injection of growth factors from your own blood into the ovary to see if it can improve egg quality and quantity for women with low ovarian reserve. It may be an option if you have been trying to conceive for over a year and have low egg reserve.
MadridAges 18–50 - NCT05263076Recruiting
Uterus transplant trial for women born without a working uterus
This trial studies uterus transplant surgery to help people with “absolute uterine factor infertility” (no working uterus) become pregnant using embryos made by IVF. It checks whether the donated uterus can support pregnancy and safe delivery for participants who meet strict medical and health requirements.
Houston, TexasAges 20–65 - NCT05726305Recruiting
Uterus transplant for women who cannot carry a pregnancy
This trial studies transplanting a uterus to allow people with uterine infertility to try pregnancy. It may help some patients who cannot carry a baby because their uterus is missing or nonfunctional, but it requires careful matching and strict health screening for both recipients and donors.
RennesAges 18 years+ - NCT06717802Recruiting
AI to predict when the womb is ready for IVF
This study uses artificial intelligence to find the best time to transfer an embryo during IVF. It may help people who have had up to 3 unsuccessful transfers before.
BudapestAges 18–40 - NCT06481696Recruiting
Resveratrol to improve IVF outcomes for unexplained infertility
This study tests whether a natural supplement called resveratrol can improve the success of IVF or ICSI for couples with unexplained infertility. You will take resveratrol during your IVF cycle to see if it helps with egg quality and pregnancy rates.
PalermoAges 18–40 - NCT07376824RecruitingPhase 3
Acupoint light therapy and Chinese medicine for ovarian reserve
This trial tests whether combining acupoint photodynamic therapy with traditional Chinese medicine can improve ovarian reserve in women with diminished ovarian reserve. It aims to find a gentle, non-hormonal way to support fertility.
Beijing, Beijing MunicipalityAges 25–40 - NCT07002346RecruitingPhase 3
Immunotherapy and bevacizumab for advanced ovarian clear cell cancer
This trial tests a combination of an immunotherapy drug (QL1706) and a targeted therapy (bevacizumab) for women with newly diagnosed advanced ovarian clear cell carcinoma. The goal is to see if this combination works better than standard treatment after surgery.
Wuhan, HubeiAges 18–75 - NCT07494877Recruiting
Anticoagulant therapy for infertility in women aged 20-45
This study looks at whether blood-thinning medication can improve the chance of pregnancy in women who have trouble conceiving. It focuses on how the medication affects the lining of the womb and its ability to accept an embryo.
Xi'an, ShaanxiAges 20–45 - NCT06622798Recruiting
Study on HRD test and PARP inhibitor for ovarian cancer
This trial looks at a genetic test called HRD to see if it can predict how well PARP inhibitors (a type of targeted therapy) work for ovarian cancer patients. It is for women who have been treated with platinum chemotherapy and are now on PARP inhibitor maintenance therapy.
Guangzhou, GuangdongAges 18 years+ - NCT05646992RecruitingPhase 2/Phase 3
Uterus transplant study to help infertility
This study tests whether transplanting a uterus can help people who cannot carry a pregnancy become pregnant and give birth. It involves surgery plus medicines to help the body accept the new organ, and then embryo transfer to try to achieve pregnancy.
Baltimore, MarylandAges 18–38 - NCT06491251Recruiting
Varicocele surgery for unexplained infertility in men
This trial tests whether surgery to remove a varicocele (enlarged veins in the scrotum) can help men with unexplained infertility and a normal sperm count become fathers. It's for men who have no other known cause of infertility.
Kafr ash ShaykhAges 18–45 - NCT04298255Recruiting
Testicular injection therapy for certain causes of male infertility
This trial studies a special lab procedure where selected immature sperm cells are injected to help infertile couples achieve pregnancy. It is designed for couples where the man has a specific type of sperm-making problem found during a testicular sperm extraction.
Winston-Salem, North CarolinaAges 18 years+ - NCT05460000RecruitingPhase 2
Niraparib after early ovarian cancer chemo—short vs long
This trial tests whether taking niraparib (a maintenance anti-cancer pill) for a shorter time after 3 cycles of platinum chemotherapy works as well as taking it after 6 cycles. It is for people with advanced ovarian cancer that has been fully removed (no visible tumor) and is “HRD-positive,” meaning it has certain DNA repair weaknesses.
InnsbruckAges 18 years+ - NCT07469007Recruiting
How surgery for deep endometriosis affects egg supply
This trial looks at how surgery for deep endometriosis behind the uterus affects a woman's egg supply (ovarian reserve). It is for women with severe deep endometriosis but without large ovarian cysts or previous surgery for this condition.
Quint-FonsegrivesAges 18–39 - NCT05071937RecruitingPhase 2
Talazoparib plus ZEN003694 for recurrent ovarian cancer
This Phase 2 trial tests whether combining ZEN003694 with talazoparib can slow or shrink recurrent ovarian, fallopian tube, or primary peritoneal cancer. It is designed for people who have already been treated with a PARP inhibitor before, and it may help if that cancer comes back.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05952453RecruitingPhase 2
New ovarian cancer treatment with chemo plus maintenance medicines
This Phase 2 trial tests giving chemotherapy before surgery, then continuing two medicines afterward (olaparib and pembrolizumab). It’s designed for people with newly diagnosed Stage III/IV ovarian, fallopian tube, or primary peritoneal cancer who may benefit from tighter control of the disease.
Birmingham, AlabamaAges 18 years+ - NCT06083844RecruitingPhase 2
Keytruda + Avastin + chemo for ovarian cancer with minimal remaining disease
This trial tests a combination of three drugs—pembrolizumab (Keytruda, an immunotherapy), bevacizumab (Avastin, a blood-vessel blocker), and oral cyclophosphamide (a chemotherapy pill)—for women with high-grade ovarian cancer who have only tiny bits of disease left after finishing their initial treatment.
New York, New YorkAges 18 years+ - NCT06234423RecruitingPhase 1
A study of CUSP06 for advanced solid tumors
This study tests a new drug called CUSP06 for people with advanced solid tumors, especially ovarian cancer that has stopped responding to platinum chemotherapy. It may help if standard treatments no longer work.
Denver, ColoradoAges 18 years+ - NCT06760923Recruiting
Urine test for ovarian cancer detection and tracking
This study looks at proteins in urine to help find ovarian cancer earlier and track how the disease changes. It aims to provide a non-invasive way to tell the difference between benign and malignant pelvic masses.
Changsha, HunanAges 18 years+ - NCT07171528RecruitingPhase 2
Surgery after chemo for recurrent ovarian cancer
This trial is for people with recurrent ovarian cancer whose disease came back more than 6 months after platinum chemo. It tests whether removing the recurrent tumor with surgery (after more chemo) can help—even if surgery wasn't an option before.
Goyang-si, Gyeonggi-doAges 19–80 - NCT07456397Recruiting
AI to predict sperm success in IVF
This trial tests a new AI system that analyzes sperm to predict how well they might work in fertility treatments like IVF or ICSI. It aims to help doctors choose the best sperm for a successful pregnancy.
Barcelona, BarcelonaAges 18–60 - NCT07669584RecruitingPhase 2/Phase 3
Testing PKB171 for mild male infertility in couples
This study tests a new oral medication (PKB171) compared to a placebo for couples who have mild male infertility and have not tried IVF/ICSI before. The goal is to see if PKB171 can help them conceive naturally.
Pamplona, NavarreAges 18–38
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Common questions
- Are there clinical trials for infertile females or females with ovarian insufficiency?
- Yes. Clin2 currently lists 166 recruiting infertile females or females with ovarian insufficiency studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a infertile females or females with ovarian insufficiency trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a infertile females or females with ovarian insufficiency trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.