Clinical trials
Intermittent Claudication clinical trials
Below are recruiting intermittent claudication clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05132439RecruitingPhase 3
Metformin to improve walking in leg artery blockage
This Phase 3 study tests whether metformin can help people with intermittent claudication (leg pain when walking) walk farther. It compares how well metformin works on walking ability alongside standard (already recommended) heart and blood-vessel medicines.
Pittsburgh, PennsylvaniaAges 35–89 - NCT06299956Recruiting
Supervised exercise for leg pain due to blocked arteries
This trial tests whether a supervised exercise program can help people with leg pain caused by blocked arteries. It may improve your walking ability and reduce pain when you walk.
SlagelseAges 18 years+ - NCT06114732Recruiting
Walking improvement study for leg pain from PAD
This study tests if a combination of a behavioral program and electrical stimulation (TENS) can help people with peripheral artery disease walk farther with less pain. It aims to boost physical activity and quality of life.
Glasgow, LanarkshireAges 18 years+ - NCT05457738Recruiting
Home walking program using a smartphone app for leg artery pain
This trial tests whether a home-based walking (exercise) plan, guided by a new smartphone app, can help people with intermittent claudication caused by blocked leg arteries. It may help improve walking comfort and ability by using a structured, app-supported exercise routine.
ReimsAges 18 years+ - NCT06657976RecruitingPhase 2
Beetroot juice and exercise for PAD
This study tests whether beetroot juice, which contains natural nitrates that help blood vessels relax, combined with exercise, can improve walking ability in people with peripheral artery disease (PAD). You might be able to join if you have PAD, can walk without a walker, and are willing to avoid beet products for a while.
Chicago, IllinoisAges 50 years+ - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT06041880Recruiting
Calf Stretching for Better Walking in PAD
This study tests whether a simple daily calf-stretching routine can improve walking ability and blood flow in people with peripheral artery disease. It offers a non-drug, non-surgical approach that you can do at home.
University Park, PennsylvaniaAges 40–85 - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06410521Recruiting
Personalized exercise program for peripheral arterial disease
This trial tests a personalized exercise program for people with peripheral arterial disease (PAD), a condition that causes leg pain when walking. The goal is to see if a tailored exercise plan can help reduce pain, improve walking distance, and boost quality of life.
Vila RealAges 18 years+ - NCT06448390Recruiting
Exercise study for leg pain from blocked arteries
This trial tests if a supervised exercise program can improve walking ability in people with leg pain caused by blocked arteries (claudication). You may qualify if you have calf pain after walking short distances that goes away with rest.
ÅlesundAges 18 years+ - NCT06529185Recruiting
Breathing device for COPD patients with leg pain
This trial tests if a breathing device (Breather) can help men with COPD who also have leg pain from blocked leg arteries (intermittent claudication) walk farther without pain. If you have both conditions, this study may offer a new way to improve your walking ability.
DokkiAges 50–60 - NCT06686121RecruitingPhase 3
Improving walking after leg artery surgery for PAD
This trial tests whether drinking beetroot juice and doing home-based exercise can improve walking ability after you've had a procedure to open up blocked leg arteries. It's for people who are ready to start a walking program and want to avoid surgery.
Tucson, ArizonaAges 18 years+ - NCT03203239Recruiting
Red light treatment for circulation problems in leg arteries
This study tests whether a red-light therapy can improve symptoms or function in people with peripheral artery disease (poor blood flow to the legs). You may qualify if your leg circulation test is abnormal and you can safely take part in the study.
Milwaukee, WisconsinAges 18–85 - NCT07588295Recruiting
How immune cells respond in heart and leg blood vessel disease
This study examines how immune cells (macrophages) behave differently in patients with blocked arteries in the heart or legs. Understanding this may help doctors develop better treatments for these conditions.
Cotignola, RavennaAges 18 years+ - NCT07672249Recruiting
Study on iliac stenting to prevent major leg events
This study looks at people with narrowed or blocked arteries in the pelvis (iliac arteries) who receive a stent to improve blood flow. It aims to understand which factors might predict future serious problems in the legs, like worsening pain or amputation.
Milan, MiAges 18 years+
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Intermittent Claudication trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for intermittent claudication?
- Yes. Clin2 currently lists 15 recruiting intermittent claudication studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a intermittent claudication trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a intermittent claudication trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.