Clinical trials
Knee Injuries clinical trials
Below are recruiting knee injuries clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06419920Recruiting
Prosthetic performance enhancement trial
This study tests whether a new prosthetic foot can help people with a lower-limb amputation walk better. You will use your current foot and the new foot, and we will measure how well you walk.
Las Vegas, NevadaAges 18 years+ - NCT04953364Recruiting
Tech-based self-management support after a leg amputation
This study tests a technology-based program to help people manage rehabilitation after a lower-limb amputation. It may help by giving structured support for day-to-day care and prosthesis use.
Vancouver, British ColumbiaAges 50 years+ - NCT06442319Recruiting
PRP after ACL reconstruction
This trial tests if injecting platelet-rich plasma (a concentration of your own blood platelets) after ACL reconstruction helps with healing and reduces pain. It's for people who recently had ACL surgery and want to try an extra treatment to improve recovery.
TorunAges 18–45 - NCT06999057RecruitingEarly Phase 1
Knee injury study for healthy active adults
This trial studies how your thigh muscle adapts after a simulated knee injury. It uses mild electrical stimulation and a small needle to measure muscle signals, and may help improve recovery after knee injuries.
Orlando, FloridaAges 18–30 - NCT05848622Recruiting
Gait retraining after ACL surgery for fast knee recovery
This trial tests a walking (gait) rehabilitation program to improve how you move after ACL reconstruction. It may help if you are still having walking mechanics issues in the months to years after surgery.
Chapel Hill, North CarolinaAges 16–35 - NCT06933706RecruitingPhase 2
Losartan for better recovery after multi-ligament knee injury
This trial tests if losartan, a blood pressure medication, can improve healing and recovery after surgery for a multi-ligament knee injury. Taking losartan for 30 days after surgery may reduce stiffness and help you get back to your normal activities sooner.
Lexington, KentuckyAges 18–40 - NCT07201597Recruiting
Readiness and knee function after ACL surgery
This study looks at how your mental readiness, knee function, and strength relate after ACL reconstruction using a specific type of tendon graft. It may help you understand if you're ready to return to sports.
Cairo, Cairo GovernorateAges 18–35 - NCT06320925Recruiting
SportsPro study after joint surgery
This study follows patients who had joint repair with specific Stryker devices to see how well the procedure works in daily life.
Phoenix, ArizonaAges 18 years+ - NCT06916728Enrolling by invitation
10-year knee implant follow-up study
This study follows patients who already took part in a previous trial for a knee implant (MP01). It checks how well the implant is working over 10 years compared to standard knee surgery.
La Mesa, CaliforniaAges 21–75 - NCT07174219Recruiting
Return to sports after MCL knee surgery
This study tracks people who had surgery to reattach the medial collateral ligament (MCL) in the knee, alone or with other repairs. It measures how well and how safely they return to sports. If you had this surgery, you may help improve future care.
Bologna, BolognaAges 12–65 - NCT04554212Recruiting
Blood flow restriction therapy after kneecap instability
This trial tests whether a special exercise method called blood flow restriction training can help people recover faster and get back to running and pivoting activities after a kneecap (patella) that slips out of place. It may help strengthen the knee while you go through physical therapy.
Lexington, KentuckyAges 14–40 - NCT06451510Recruiting
Knee osteoarthritis study in Northern Sweden
This trial studies knee osteoarthritis in people from Norrbotten, Sweden, who broke their tibial plateau between 2001 and 2015. It aims to understand how the injury affects the knee over time.
Luleå, Norrbotten CountyAges 18 years+ - NCT07212920Recruiting
Video physiotherapy for recent knee injuries
This study tests whether a video-based physiotherapy assessment works as well as an in-person exam for people with recent knee injuries. If you have a knee injury that started 1 to 12 weeks ago and haven't been treated yet, you may be able to participate from home using your phone or computer.
AlingsåsAges 18 years+ - NCT03932838Recruiting
Study of knee ligament reconstruction outcomes after injury
This study looks at how people do after one-time surgery to repair multiple knee ligaments using either donor tissue or their own tissue. It helps doctors better understand what to expect after multiligament knee reconstruction.
Le ChesnayAges 18 years+ - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT07501013Recruiting
Shoulder and knee surgery outcomes study
This study looks at how well different types of shoulder and knee surgeries work for sports injuries. It aims to help improve future care by following patients' recovery after common procedures like fixing torn cartilage or repairing ligaments.
Hangzhou, ZhejiangAges 8–80 - NCT05344001Recruiting
Study links past sports injuries and low activity to later health
This study looks at how an earlier sports injury and time spent being inactive may relate to later health problems. It mainly needs specific age groups and either current/former collegiate athletes or non-athlete comparison participants.
Milwaukee, WisconsinAges 18–64 - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT06571227Recruiting
Understanding knee scores after ACL surgery
This study aims to find what a 'normal' knee score (Lysholm score) means for people after ACL surgery. It will help doctors know if your recovery is on track.
AnkaraAges 18 years+ - NCT06770153Recruiting
A trial comparing two knee replacement balancing techniques
This study compares a special tensioning tool to the standard method for balancing a new knee joint during total knee replacement. It aims to see which technique provides better outcomes.
BolognaAges 50–85 - NCT06562634Enrolling by invitation
Ultrasound-guided nerve block for knee surgery pain relief
This study tests a nerve block (erector spinae plane block) to see if it reduces pain after open knee surgery. It aims to find a better way to manage pain with fewer side effects.
CairoAges 18–65 - NCT06893302Recruiting
Bone marrow injection during knee scope for cartilage or meniscus
This trial tests if adding a bone marrow injection to standard knee arthroscopy helps your knee heal better. It is for people with a torn meniscus or damaged cartilage who have healthy knee joints without arthritis.
New York, New YorkAges 18–64 - NCT06937242Recruiting
Testing a smarter prosthetic knee for safer walking
This study tests whether a microprocessor-controlled knee can reduce falls in people who walk limited distances. If you use a regular mechanical knee and have a moderate activity level, this trial might help you walk more safely.
Austin, TexasAges 18 years+ - NCT03858231RecruitingPhase 4
Opioid vs non-opioid pain relief after knee arthroscopy
This study compares opioid pain medicine with non-opioid pain medicine after arthroscopic (keyhole) knee surgery. It aims to see which approach controls pain well while keeping side effects and risks lower.
Fargo, North DakotaAges 18–80
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Common questions
- Are there clinical trials for knee injuries?
- Yes. Clin2 currently lists 70 recruiting knee injuries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a knee injuries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a knee injuries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.