Clinical trials
Light clinical trials
Below are recruiting light clinical trials, each written for real people, not researchers. We’re tracking 277 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07457749RecruitingEarly Phase 1
Comparing two tooth-colored fillings for back teeth cavities
This study tests a new self-hardening filling material against a light-activated bioactive filling for cavities between back teeth. The goal is to see which material works better and lasts longer.
Cairo, El Sherouk CityAges 18–47 - NCT07176429Enrolling by invitation
Comparing two light adjustable lenses after cataract surgery
This study compares how well two types of light adjustable lenses (LAL and LAL Plus) help you see at different distances after cataract surgery, compared to a standard lens. It aims to see if the light adjustable lens can reduce the need for glasses.
Valencia, CaliforniaAges 18 years+ - NCT06735014Recruiting
ALS imaging study to track disease progression
This study uses MRI brain scans to understand how ALS affects the brain over time. It may help researchers develop better ways to measure the disease.
Gainesville, FloridaAges 18 years+ - NCT06382324Recruiting
Mindfulness for knee recovery after ACL surgery
This study tests whether practicing mindfulness within the first month after ACL (anterior cruciate ligament) surgery can help with your mental well-being during recovery. You'll learn techniques to stay calm and focused.
Keelung, TaiwanAges Any age - NCT06088355Recruiting
Comparing exercise amounts for moderate Parkinson's
This study compares two different amounts of light-to-moderate exercise to see which is better for people with moderate Parkinson's disease. It involves walking or doing similar activities at a comfortable pace, either a moderate amount or a higher volume, over several weeks.
Decatur, GeorgiaAges 40 years+ - NCT07425119Recruiting
Quit smoking trial for people who smoke a little each day
This study tests a text message program to help people who smoke 1-10 cigarettes most days but not daily quit. It uses cues and reminders sent to your phone to support your quit attempt.
Durham, North CarolinaAges 18 years+ - NCT07719140RecruitingPhase 4
Lower steroid dose study for children with lupus nephritis
This trial tests whether a lower starting dose of steroids can control kidney inflammation in children with lupus nephritis. It aims to reduce side effects while still treating the disease effectively.
Beijing, Beijing MunicipalityAges 6–18 - NCT07224672RecruitingPhase 2
Study of a drug combo for newly diagnosed AL amyloidosis
This trial tests a combination of four drugs (belantamab mafodotin, cyclophosphamide, bortezomib, and dexamethasone) for people newly diagnosed with AL amyloidosis who cannot have a stem cell transplant. The goal is to see if this combination is safe and effective at stopping the abnormal proteins from damaging your organs.
Rochester, MinnesotaAges 18 years+ - NCT06780150Recruiting
Ocrelizumab effects on nerve health and satisfaction in MS
This study looks at how ocrelizumab treatment affects a nerve health marker called neurofilament light chain (NfL) and how satisfied you are with the treatment. It may help doctors understand if this medicine works well for people with multiple sclerosis.
AachenAges 18 years+ - NCT03482245Recruiting
Study how body clock proteins affect immune responses in infections
This study looks at how your body’s daily “clock” proteins may influence your immune response during certain serious infections requiring hospital care. If you qualify, researchers will compare immune signals during treatment to better understand what could improve care.
St Louis, MissouriAges 18–65 - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT03717844Recruiting
Registry for adults with plasma cell disorders
This study is a registry that collects information about adults with plasma cell disorders (conditions involving abnormal antibody-producing cells). It may help researchers understand these diseases better and improve future care by tracking patients over time.
Chapel Hill, North CarolinaAges 18 years+ - NCT03981003Recruiting
Blood tests to track brain and nerve changes in MS
This study measures blood markers (from a serum blood sample) to see how nerve and brain changes relate to MS disease activity and disability over time. It may help researchers better monitor MS, especially in people followed in the OFSEP program.
AmiensAges 15 years+ - NCT04114994Recruiting
Memory testing study for adults 50 and older
This study checks how people’s thinking and memory change over time using a specific cognitive test. It may help researchers understand patterns of memory change and supports future research on brain health.
Miami, FloridaAges 50 years+ - NCT04358913Recruiting
MRI scan study during radiation treatment planning
This study looks at how an MRI scanner can be used alongside a radiation treatment machine to plan therapy. It may help improve how radiation is targeted, though joining is mainly about whether you can safely and comfortably complete the MRI scans.
Edmonton, AlbertaAges 18 years+ - NCT07110844RecruitingPhase 2
Teclistamab with Daratumumab for Newly Diagnosed AL Amyloidosis
This trial tests a combination of two drugs (teclistamab and daratumumab) for people with AL amyloidosis who have not had prior treatment. The goal is to see if this combination can safely and effectively reduce the abnormal protein deposits in organs.
Boston, MassachusettsAges 18–100 - NCT04946916Recruiting
Testing blood/brain marker levels and thinking problems in psychiatric illness
This study looks at neurofilament light (a brain/nerve injury marker) and how it relates to thinking and memory problems in people with certain psychiatric conditions. It may help researchers understand brain changes and cognitive impairment, which could guide better diagnosis in the future.
BronAges 45–80 - NCT05127265Recruiting
AI and sensors to monitor patients in the ICU
This study uses AI and sensor data to better monitor people while they are in an intensive care unit (ICU). It may help teams notice changes sooner and improve care for ICU patients.
Gainesville, FloridaAges 18 years+ - NCT05268887Recruiting
Light, sound, and touch therapy for Parkinson’s symptoms
This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.
Cambridge, MassachusettsAges 45–90 - NCT05283993Recruiting
Hospital study following people with plasma cell disorders
This is a hospital-based study that follows people with plasma cell disorders to better understand these conditions. It mainly gathers information from patients who are confirmed to have one of several related diseases.
BeijingAges Any age - NCT05403554RecruitingPhase 1
Testing a new mesothelin-targeting drug for certain solid cancers
This Phase 1 study tests NI-1801, a drug designed to attach to a target on cancer cells (mesothelin). It may be given alone or with pembrolizumab to help shrink tumors in advanced cancers that have enough mesothelin on their cells.
ParisAges 18 years+ - NCT05413473RecruitingPhase 1/Phase 2
Testing image-guided radiotherapy using MRI scans
This trial studies a way of planning and delivering radiation using MRI pictures to help target tumors more accurately. It may benefit people by improving how radiation is aligned, and it’s being tested for safety and effectiveness compared with the usual CT-based planning.
Edmonton, AlbertaAges 18 years+ - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT05655195Recruiting
At-home light and sound therapy for mild Alzheimer’s
This study tests whether regular at-home “gamma” light and sound stimulation can help people with mild Alzheimer’s. Participants start with a month at home and are followed to see how they do during treatment.
Cambridge, MassachusettsAges 65–100
Hear when a new Light trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for light?
- Yes. Clin2 currently lists 277 recruiting light studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a light trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a light trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.