Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04036357Recruiting
Study of liver fat disease with heart and metabolism problems
This study looks at people with fatty liver disease and common health issues like obesity, diabetes, high blood pressure, or abnormal cholesterol. It may help researchers understand how liver fat and heart/metabolism problems relate and how they affect health over time.
RomeAges 18–80 - NCT04037995Recruiting
Real-world study of advanced liver disease in China
This study looks at people with very advanced liver problems to better understand what happens in real life. It may help doctors improve care for advanced cirrhosis and certain liver cancers.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04054310Recruiting
Test MRI to measure liver fat and NASH using biopsy
This study checks whether an MRI scan can measure liver health in people with suspected fatty liver disease that may have progressed to NASH. Everyone in the study is also scheduled for a standard liver biopsy, which is used to compare the scan results.
Chandler, ArizonaAges 18–75 - NCT04073290RecruitingPhase 4
Rifaximin and lactulose to prevent confusion after TIPS
This trial studies whether taking rifaximin plus lactulose can prevent a brain problem called hepatic encephalopathy (confusion) after TIPS, a procedure to reduce pressure in the liver. It may help people who are having TIPS planned and are at risk of this complication.
LeuvenAges 18–80 - NCT04079049RecruitingPhase 3
Local treatment for breast cancer spread to the liver
This study tests a local (targeted) approach for breast cancer that has spread to the liver. It looks at whether treating liver metastases with planned liver surgery, along with standard cancer treatment before and after, can improve outcomes.
UmeåAges 18 years+ - NCT04106518Recruiting
Genetics study of alcohol-related liver disease and cirrhosis
This study looks at genetic differences in people with alcohol-related liver illness, including a recent jaundice episode (alcoholic hepatitis). By following people over time, it may help doctors better predict illness and understand why some people develop worse liver problems.
AngersAges 18 years+ - NCT04134559RecruitingPhase 2
Pembrolizumab for kids with liver cancer that came back
This trial studies pembrolizumab (an immune therapy) in children and young people with hepatocellular carcinoma (HCC) that has returned or did not respond to earlier treatment. The goal is to see whether it can shrink tumors and help control the cancer.
San Francisco, CaliforniaAges birth–30 years - NCT04141592Recruiting
Study immune and disease changes in fatty liver
This study looks at what drives non-alcoholic fatty liver disease and how it affects the body, including immune-related changes. You may be invited if you have confirmed fatty liver disease or, alternatively, if you are a healthy person with no liver disease.
London, Greater LondonAges 18 years+ - NCT04204850RecruitingPhase 2
Cabozantinib for liver cancer that returns after liver transplant
This trial studies cabozantinib, a cancer medicine, for liver cancer that has come back after a liver transplant. It’s for people whose cancer can’t be cured with more surgery or local procedures, to see if the treatment can help control the disease.
Toronto, OntarioAges 18 years+ - NCT04310787Recruiting
Tracking outcomes in adults with hepatitis B liver failure
This study looks at long-term survival in people ages 18–65 who are hospitalized with hepatitis B–related acute-on-chronic liver failure. It may help doctors better predict prognosis and improve care for people with this serious condition.
Guangzhou, GuangdongAges 18–65 - NCT04320199Recruiting
Fermented beetle powder for alcohol-related liver problems
This trial tests whether a fermented powder made from a specific beetle can improve or protect the liver after alcohol-related liver injury. It’s looking for people with certain liver blood test levels, and it excludes several conditions and recent herbal or liver-affecting treatments.
Pusan, Ami-dongAges 19 years+ - NCT04340817Recruiting
Study of fatty liver in Nordic countries
This study looks at people with non-alcoholic fatty liver disease (fat buildup in the liver without heavy alcohol use). It may also include healthy volunteers for comparison, helping researchers understand the condition better.
Hvidovre, Capital Region DenmarkAges 18 years+ - NCT04365855Recruiting
Study of fatty liver risk in local adults
This study looks at how common fatty liver disease is and what factors may be linked to it in adults in Olmsted County. You may be asked about health history, alcohol use, and possibly to undergo MRI scans.
Rochester, MinnesotaAges 18 years+ - NCT04400604Recruiting
Study of liver disease risk from heavy alcohol use
This study looks at people with heavy alcohol use who may have alcohol-related liver damage. It aims to better understand liver disease risk and how it changes over time, using blood tests, some scans, and possibly stored tissue.
LilleAges 18–75 - NCT04429100Recruiting
Breath-hold MRI test to measure liver scar levels
This study tests an MRI technique that briefly holds your breath to measure how scarred your liver tissue is. It may help doctors better spot and track liver fibrosis (scarring).
Hong Kong, ShatinAges Any age - NCT04442334Recruiting
European registry for people with fatty liver
This registry collects health and lifestyle information from adults with suspected or confirmed fatty liver (NAFLD) to help researchers better understand the condition. You may be asked about diet, exercise, alcohol intake, and some liver-related tests.
AntwerpAges 18–100 - NCT04446832Recruiting
Vaccine study for people waiting for liver transplant
This study tests a vaccine strategy for people who are being evaluated and waiting for a liver transplant. The goal is to see how well the immune system responds and how the results are interpreted before transplant.
LyonAges 18 years+ - NCT04448028RecruitingPhase 4
Stopping acid pills in liver cirrhosis: test placebo effect
This study tests whether stopping proton-pump inhibitor (PPI) acid-reducing medication is safe and works as expected for people with liver cirrhosis. Participants switch to either the study medication or a placebo (inactive pill) under close monitoring.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT04455932Recruiting
Test shorter MRI versus ultrasound for liver cancer screening
This study compares a shorter, non-contrast MRI and ultrasound to monitor for liver cancer in people with cirrhosis whose ultrasound images aren’t clear enough. It aims to see which method works better and may help you get safer, more reliable follow-up.
Camperdown, New South WalesAges 20–85 - NCT04499833Recruiting
Test an AI score to guide liver transplant decisions
This study looks at a prediction tool that estimates outcomes for people with liver cancer and cirrhosis, to help decide whether a liver transplant is a good option. It may help doctors choose the right timing and patients who could benefit most from transplantation.
LisbonAges 18–70 - NCT04502719Recruiting
Testing nutrition screening in people with liver cirrhosis
This study compares different ways of checking nutrition problems in people with liver cirrhosis. It may help doctors choose the best screening tool to spot risk earlier and guide care.
Barcelona, CataloniaAges 18–100 - NCT04556214Recruiting
Liver transplant test for certain bile duct cancers
This trial studies whether a liver transplant can help people with a non-removable type of bile duct cancer in the liver. To be eligible, the cancer must be in the liver only (no spread), and you typically must already have had at least 6 months of treatment before being listed for transplant.
OsloAges 18 years+ - NCT04573283Recruiting
Study of fatty liver in adults in China
This study follows adults with fatty liver to learn more about how it progresses and what patterns are common. It may help improve future ways of identifying and monitoring fatty liver.
Guangzhou, GuangdongAges 18–80 - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.