Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,254 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06061276Recruiting
Combined therapy for large liver cancer with limited spread
This trial tests a combination of treatments—bland transarterial embolization (bTAE), hepatic artery infusion chemotherapy (HAIC), and systemic therapy—for people with large liver cancers that have limited spread. It might be an option if you have a big tumor and your liver is still working well.
Guanzhou, GuangdongAges 18–75 - NCT06070636Recruiting
Triple therapy for aggressive liver cancer
This trial tests a combination of three treatments for a specific type of aggressive liver cancer called infiltrative hepatocellular carcinoma (HCC). It combines targeted therapy (lenvatinib), immunotherapy (sintilimab), and a procedure that delivers chemotherapy directly to the liver (bTAE-HAIC). The goal is to see if this triple approach works better for people with large tumors or those that have spread to the portal vein.
Guangzhou, GuangdongAges 18–75 - NCT06078098Recruiting
Autoimmune Hepatitis Database and Biobank Study
This study is building a database and collection of samples from people with autoimmune hepatitis in Italy. It aims to learn more about the disease and improve care.
Monza, MBAges 1 year+ - NCT06091423RecruitingPhase 2
XELOX plus fruquintinib and sintilimab for stomach cancer with liver or lymph node spread
This trial tests a combination of chemotherapy (XELOX), a targeted therapy (fruquintinib), and an immunotherapy (sintilimab) to shrink stomach cancer that has spread only to the liver or retroperitoneal lymph nodes. The goal is to make the cancer removable by surgery.
NanjinAges 18–75 - NCT06092385Recruiting
Swiss cirrhosis study for liver patients and controls
This study compares patients with advanced liver scarring (cirrhosis) to healthy controls to learn more about the condition. It may help researchers better understand and manage liver disease.
Lugano, Canton TicinoAges 18 years+ - NCT06093022Recruiting
Treatment options for breast cancer that has spread to the liver
This study looks at how breast cancer that has spread to the liver responds to different treatments, including surgery and medicines. The goal is to learn which approach works best for patients with this condition.
Rome, LazioAges 18 years+ - NCT06095466Recruiting
Heart check with ultrasound in severe liver disease
This study tests if a simple bedside heart ultrasound (echocardiogram) and blood tests can spot early heart problems in people with severe liver disease (cirrhosis) who are in the intensive care unit. It may help doctors better understand and manage heart complications in cirrhosis.
Sector-12, ChandigarhAges 18–65 - NCT06111105Recruiting
Comparing blood tests to guide colon cancer treatment
This study compares different blood tests to find the best way to detect tiny bits of cancer DNA after surgery for stage III colorectal cancer. It aims to help doctors decide if additional chemotherapy is needed to prevent the cancer from coming back.
Graz, StyriaAges 18 years+ - NCT06115876Recruiting
Kuwait diabetes long-term follow-up study
This study checks in on people with prediabetes or type 2 diabetes who were part of an earlier Kuwait diabetes study. It aims to understand how their condition has changed and what health care they may need.
Kuwait CityAges 21–75 - NCT06119997Recruiting
Liver fibrosis screening using simple blood tests in primary care
This trial uses a blood test (FIB-4) to find liver scarring (fibrosis) in people who haven't been tested before. It aims to catch advanced liver disease early, which can help you get treatment sooner.
GrenobleAges 18–70 - NCT06124456Recruiting
Vigorous vs. moderate exercise for liver fat reduction
This study compares high-intensity exercise to moderate-intensity exercise to see which is better at reducing fat in the liver for people with obesity and fatty liver disease.
Hong KongAges 18–69 - NCT06144593Recruiting
Carb cutting for people with type 2 diabetes
This study looks at whether cutting carbs on certain days can improve metabolism for people with type 2 diabetes. It may help if you have mild to moderate diabetes and are overweight or obese.
HvidovreAges 35–75 - NCT06160635Recruiting
D-SOLVE: Study of Hepatitis D treatments
This trial is testing treatments for people with chronic hepatitis D, a serious liver infection. If you have antibodies to the hepatitis D virus (HDV), you may be able to join and help find better ways to manage this condition.
HanoverAges 18 years+ - NCT06174272Recruiting
Better care after hospital for liver swelling
This trial tests a program to help people with cirrhosis and severe fluid swelling get better care after leaving the hospital. It focuses on guiding you through treatment with water pills and managing fluid buildup at home.
Hershey, PennsylvaniaAges 18 years+ - NCT06184152Recruiting
Comparing two scans to find liver cancer early
This trial compares two types of imaging scans (CEUS and AMRI) to see which one is better at finding liver cancer (HCC) in patients who have an unclear spot on their liver (an indeterminate nodule). It is for people with cirrhosis who have at least one such nodule but no confirmed liver cancer yet.
Ann Arbor, MichiganAges 18 years+ - NCT06191120Recruiting
FAPI PET scan for aggressive colorectal cancer liver metastases
This trial uses a special PET scan (FAPI) to detect a specific, more aggressive type of colorectal cancer (CMS4) in people who have liver tumors that can be surgically removed. The goal is to see if the scan can help doctors choose the best treatment for you.
Utrecht, UtrechtAges 18 years+ - NCT06196294RecruitingPhase 1
Engineered immune cells for cancers with GPC3 or mesothelin
This trial tests a new type of immune cell therapy made from your own cells (gamma-delta T cells) that are engineered to find and attack cancers that have GPC3 or mesothelin proteins. It may be an option for people with advanced cancer who have not had gene therapy before and are in generally good health.
Guangzhou, GuangdongAges 18–75 - NCT06198296RecruitingPhase 1
Armored CAR T cells for GPC3-positive solid tumors
This trial tests a new type of immunotherapy called CAR T cells that are trained to find and attack cancer cells with a specific marker (GPC3). The CAR T cells are also 'armored' with extra proteins (IL-15 and IL-21) to help them work better. It might be an option for adults with advanced solid tumors, especially liver cancer, that have not responded to standard treatments.
Houston, TexasAges Up to 21 years - NCT06203548Recruiting
Tracking liver fat with a continuous monitor
This study looks at a new way to track how much fat is in your liver using a simple, continuous device. It may help people with fatty liver disease and related metabolic issues (like being overweight or having high blood sugar) avoid frequent MRI scans.
Hong KongAges 18–65 - NCT06208397Recruiting
MRI study to understand liver tumor growth patterns
This trial uses MRI scans to study how colorectal cancer that has spread to the liver grows. It may help doctors choose better treatments.
Shenyang, LiaoningAges 18–80 - NCT06211556Recruiting
Reducing liver fat in type 2 diabetes
This study tests whether reducing liver fat can improve health in people with type 2 diabetes. It looks at the effects of a specific medication combined with exercise, tailored for those who are not very active.
Copenhagen, Capital RegionAges 30–70 - NCT06211868Recruiting
Early heart disease risk study for adults 40-70
This study looks at whether changing your immune system, fats, and metabolism can lower your risk of early heart disease. It is for people with an intermediate to high risk score but who have not yet had a heart attack or stroke.
SingaporeAges 40–70 - NCT06218420RecruitingPhase 2
Radiation to bridge to liver transplant
This study tests whether a precise type of radiation (called stereotactic body radiotherapy or SBRT) can be used as a 'bridge' to keep your liver cancer from growing while you wait for a liver transplant. It may help more people stay healthy enough to receive a transplant.
ParisAges 18 years+ - NCT06225843RecruitingPhase 2
Testing a new drug combo before liver surgery for colorectal cancer
This trial is for people with colorectal cancer that has spread to the liver. It tests whether adding a new drug (sotevtamab) to standard chemotherapy (FOLFOX) before surgery can help shrink tumors and improve outcomes.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,254 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.