Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,252 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06265350Recruiting
Freezing lung tumors plus immunotherapy for liver cancer with lung spread
This study tests a combination of treatments—freezing the lung tumors (cryoablation) plus two drugs (cardonilizumab and bevacizumab)—for people with liver cancer that has spread only to their lungs. It may be an option if your first treatment stopped working but your liver tumors are under control.
Guanzhou, GuangdongAges 18–75 - NCT06266260Recruiting
Measuring liver pressure with ultrasound for advanced liver disease
This trial uses a minimally invasive ultrasound technique to directly measure blood pressure in the liver's main vein. It may help doctors decide if patients with severe scarred livers need medication to prevent variceal bleeding.
RomaAges 18–99 - NCT06280495RecruitingPhase 2/Phase 3
Targeted drugs plus chemo before surgery for colon cancer with liver spread
This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.
Guangzhou, GuangdongAges 18–75 - NCT06290154Recruiting
Heart health after liver transplant study
This study looks at factors that affect heart health after a liver transplant. It may help doctors better predict and manage heart problems in people with end-stage liver disease who are getting a new liver.
Guangzhou, GuangdongAges 18 years+ - NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT06307080Recruiting
Combined ablation and immunotherapy for pancreatic cancer with liver spread
This study tests a new treatment combining tumor destruction with heat/cold (ablation) and an immunotherapy drug (PD-1) for people whose pancreatic cancer has spread to the liver. The goal is to help the immune system fight the cancer better.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06307964Recruiting
Gut bacteria in alcoholic hepatitis
This trial is looking at bacteria inside the liver of people with alcoholic hepatitis. It may help understand how these bacteria affect the disease and lead to better treatments.
LyonAges 18 years+ - NCT06308757Recruiting
Studying a very low calorie keto diet for fatty liver disease with scarring
This trial tests whether a very low calorie ketogenic diet (a strict low-carb, high-fat diet) can help people with non-alcoholic steatohepatitis (NASH) who have liver scarring. Participants will follow this diet for a year and have two liver biopsies to see if their liver health improves.
BolognaAges 18 years+ - NCT06316154Recruiting
Liver cyst wall study during echinococcosis surgery
This study looks at parts of the liver cyst wall during surgery for echinococcosis. It aims to learn more about the infection to help future treatments.
Tashkent, UzbekistanAges 18–80 - NCT07694843RecruitingPhase 1
Study of ammoxetine for people with mild to moderate liver problems
This trial tests how the body processes ammoxetine in people with mild or moderate liver impairment compared to people with normal liver function. It aims to find out if the drug is safe and how it works in these groups.
Suzhou, JiangsuAges 18–75 - NCT05181826Recruiting
Blood collection study for cancer and benign diseases
This study collects blood samples from people with different health conditions (cancer, diabetes, liver disease, etc.) and from healthy volunteers. The goal is to find markers in the blood that could help detect or monitor diseases.
Redondo Beach, CaliforniaAges 18 years+ - NCT03942328RecruitingPhase 1/Phase 2
Immune cell vaccine plus checkpoint treatment after liver radiation
This trial tests a combination of a personalized immune cell treatment (made from your own cells) and a pneumococcal vaccine along with an “immune checkpoint” drug after high-dose radiation for certain unresectable liver cancers. The goal is to help your immune system better attack the cancer and to see how safe and effective this approach is.
Rochester, MinnesotaAges 18 years+ - NCT05881005Recruiting
NAC for fatty liver in people with active Cushing’s
This study tests whether NAC (a supplement/medicine) can improve liver health in adults who have active Cushing’s syndrome and fatty liver disease. It may help if your excess stress hormone levels are affecting your liver.
AngersAges 18 years+ - NCT07341737RecruitingPhase 1/Phase 2
SL-28 for advanced solid tumors that haven’t responded to treatment
This trial tests a new drug, SL-28, for people with advanced solid tumors that haven’t responded to or cannot be treated with standard therapies. It aims to find a safe dose and see if the drug can help shrink or slow the growth of your cancer.
Adelaide, South AustraliaAges 18 years+ - NCT06326502RecruitingPhase 1
A study of ETN101 for advanced liver cancer
This trial tests an experimental oral drug (ETN101) for adults with advanced liver cancer (hepatocellular carcinoma) that has gotten worse after standard treatments or can't be treated with standard therapy. It aims to see if the drug is safe and effective.
SeoulAges 19–65 - NCT06328517Recruiting
Nutrition and liver cirrhosis: a study of outcomes
This study looks at how nutrition affects the health of people with liver cirrhosis (scarred liver) and aims to build a tool to predict their outcomes. If you have cirrhosis, joining may help researchers find better ways to support your health.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06341270Recruiting
Electric acupressure for pain after liver surgery
This trial tests if a gentle electric stimulation on the skin (TEAS) can reduce pain and speed up recovery after liver surgery. The treatment is non-invasive and may be an alternative to pain medicines.
Chengdu, SichuanAges 18–80 - NCT06341543Recruiting
CMV blood test to guide treatment after organ transplant
This study uses a blood test (QuantiFERON-CMV) to help decide whether people with a silent (no symptoms) CMV infection after a solid organ transplant need treatment. If you have a low-to-moderate level of CMV in your blood without fever or organ issues, this trial may help your doctor choose the safest approach.
Grenoble, MarylandAges 18 years+ - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06364930RecruitingPhase 4
SGLT2 inhibitor to prevent liver problems in hepatitis B and diabetes
This study tests if adding a diabetes medicine called an SGLT2 inhibitor to your current treatment can help prevent liver complications in people with chronic hepatitis B and type 2 diabetes or prediabetes. If you have early liver scarring and stable diabetes treatment, this could offer extra protection for your liver.
Hong KongAges 18 years+ - NCT06367244Recruiting
Wellness Program for Transplant Wait-List Patients
This trial offers a wellness program to help people waiting for a kidney or liver transplant improve their health and fitness. You'll receive support and guidance through virtual sessions.
Calgary, AlbertaAges 18 years+ - NCT06372015Recruiting
Diet program vs bariatric surgery for liver health
This study compares two ways to help people with obesity and liver problems: a special diet program or weight-loss surgery. Researchers will look at changes in fats, immune system, and genetic markers to see which approach works better.
Castellana Grotte, BariAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,252 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.