Clinical trials
Low Back Pain clinical trials
Below are recruiting low back pain clinical trials, each written for real people, not researchers. We’re tracking 345 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07590050Recruiting
Catgut Embedding for Lower Back Pain and Blood Stasis
This trial tests catgut embedding (a traditional acupuncture technique using absorbable material) to treat chronic lower back pain caused by spine wear-and-tear, particularly for patients whose condition matches a traditional medicine pattern called 'blood stasis.' The goal is to see if this approach relieves pain and improves movement.
Ho Chi Minh City, Ho Chi Minh CityAges 18–65 - NCT05641948Recruiting
Tested nerve ablation plus brain scans for ongoing back pain
This trial studies a procedure called radiofrequency denervation to reduce long-lasting, mostly “pain-from-joints/structures” low back pain, and it uses brain imaging to understand what changes during treatment. It may help people who already showed they respond well to a similar diagnostic nerve block.
Aberdeen, ScotlandAges 18 years+ - NCT06751160Recruiting
Dry needling vs. soft tissue massage for tight hamstrings
This study compares two treatments—dry needling and soft tissue massage—to see which works better for relieving tight hamstring muscles in people with low back pain.
Lahore, Punjab ProvinceAges 20–40 - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55 - NCT06715085RecruitingPhase 4
PRGF injections for chronic low back pain
This trial tests whether injections of a blood-based treatment called PRGF can help people with long-term low back pain caused by worn discs. It is for those who haven't gotten relief from standard treatments like medication.
Vitoria-Gasteiz, AlavaAges 18 years+ - NCT07414017Recruiting
Virtual reality exercise for older adults with low back pain
This study tests if using virtual reality during exercise helps older adults with long-term low back pain. You'll do exercises while focusing your attention in different ways, and researchers will see which method works best for reducing pain and improving movement.
Center, Kirşehi̇rAges 65–80 - NCT07313566Recruiting
Rehab pathway vs usual care after lumbar spine surgery
This trial compares a new rehab program called R3 (which includes pre-surgery preparation and post-surgery recovery support) with standard care for people having lumbar spine surgery. It aims to see if the R3 pathway helps you recover better and return to work faster.
AntwerpAges 18–65 - NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55 - NCT07224945Recruiting
Emergency room physical therapy for low back pain
This study tests whether physical therapy in the emergency room can help people with new or recent low back pain. If you have back pain that started in the last month, you may be able to join.
Chicago, IllinoisAges 18 years+ - NCT06347991Recruiting
Chiropractic self-care app study for back pain in Alberta
This study tests an app called SelfBack that helps chiropractic patients manage their own long-term low back pain. You will use your smartphone to receive personalized exercises and tips. It may help you take control of your back pain between chiropractic visits.
Edmonton, AlbertaAges 18 years+ - NCT07205991Recruiting
Ways to stick with a back-pain mobile app
This trial tests strategies to help people with chronic low back pain use a mobile health app consistently. If you have ongoing back pain and participated in the NOTUS trial, this study might show you better ways to stay engaged with the app.
Sydney, New South WalesAges 18 years+ - NCT07173413Recruiting
Quality of phone check-ins after spine surgery
This study checks how well telephone follow-ups work for patients who had lower back surgery at a Danish hospital. It may help improve future care.
Aalborg, AalborgAges 18 years+ - NCT07094997Recruiting
Massage therapy for healthcare workers with low back pain
This study tests if massage therapy can help healthcare workers with ongoing low back pain. If you qualify, you would receive several massage sessions to see if they reduce your pain and improve your well-being.
Wroclaw, Lower Silesian VoivodeshipAges 30–65 - NCT07085247Recruiting
Role of bacteria in lower back disc disease
This trial looks at whether a specific bacteria, Cutibacterium acnes, is linked to disc problems in the lower back. If you're having surgery for a herniated disc, your tissue sample may help researchers understand the cause.
BrnoAges 18 years+ - NCT06666621RecruitingPhase 4
Naloxone injection for low back pain
This trial tests whether naloxone, a drug that blocks opioid effects, can change how your body responds to pain injections in the lower back. It may help find new ways to treat low back pain that hasn't improved with physical therapy or oral medications.
Nashville, TennesseeAges 18 years+ - NCT06053255Recruiting
Testing a new device for low back pain from sacroiliitis
This trial tests a device called the Neurolyser XR to treat chronic low back pain caused by inflammation of the sacroiliac joint. It may help if you've had pain for over a year and other treatments haven't worked.
Charlottesville, VirginiaAges 18 years+ - NCT07003802Enrolling by invitation
Understanding back muscle control in disc injury
This study looks at how the brain controls back muscles in people with chronic disc injuries. It compares patients before surgery or physical therapy to healthy controls to better understand muscle function.
La Jolla, CaliforniaAges 18–60 - NCT07010991Recruiting
AI teaching to improve clinical reasoning skills
This trial tests if an AI-based educational method helps undergraduate students develop better clinical reasoning skills. It compares this approach to standard learning.
Istanbul, Kavacık BeykozAges Any age - NCT06977958Enrolling by invitation
Gluteal enhancement trial for non-active women
This trial tests a program called NASM OPT to see if it can improve hip appearance in women who haven't exercised for the last 6 months. It might help you if you're looking to reshape your hips safely.
Ferdows, South Khorasan ProvinceAges 20–45 - NCT06982573Recruiting
Magnetic Stimulation for Low Back Pain in Dialysis Patients
This trial tests whether magnetic stimulation can help relieve low back pain and help maintain muscle mass in people with end-stage kidney disease who are on dialysis. It is for those who have moderate to severe low back pain and are otherwise healthy enough for the procedure.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06977919Enrolling by invitation
New exercise method for chest firmness and shape
This trial tests a new technique (called NASM OPT) to help improve the shape and firmness of your chest. It is for women who have not been exercising and who want to enhance their chest appearance without using surgery.
Zahedan, Sistan and BaluchestanAges 20–45 - NCT06965920Enrolling by invitation
Spinal pain and balance study using gentle chiropractic care
This study tests a gentle chiropractic technique called flexion distraction to see if it improves how well you move and balance while standing. It may help if you have spinal pain and can stand with mild to moderate pain.
West Palm Beach, FloridaAges 18–100 - NCT06956664Recruiting
Exercise after steroid injection for herniated disc
This study tests whether adding a structured exercise program after a steroid injection for a herniated disc in the lower back helps reduce pain and improve function better than the injection alone. You may be eligible if you recently had the injection but still have significant pain.
ÇankırıAges 18–70 - NCT06928740Recruiting
Music app vs. gas for anxiety during back injection
This trial tests whether listening to a digital music app can reduce anxiety as well as a standard gas (laughing gas) does in people getting a CT-guided back injection for low back pain.
NîmesAges 18 years+
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Common questions
- Are there clinical trials for low back pain?
- Yes. Clin2 currently lists 345 recruiting low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.