Clinical trials
Low Back Pain clinical trials
Below are recruiting low back pain clinical trials, each written for real people, not researchers. We’re tracking 348 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06965920Enrolling by invitation
Spinal pain and balance study using gentle chiropractic care
This study tests a gentle chiropractic technique called flexion distraction to see if it improves how well you move and balance while standing. It may help if you have spinal pain and can stand with mild to moderate pain.
West Palm Beach, FloridaAges 18–100 - NCT06956664Recruiting
Exercise after steroid injection for herniated disc
This study tests whether adding a structured exercise program after a steroid injection for a herniated disc in the lower back helps reduce pain and improve function better than the injection alone. You may be eligible if you recently had the injection but still have significant pain.
ÇankırıAges 18–70 - NCT06928740Recruiting
Music app vs. gas for anxiety during back injection
This trial tests whether listening to a digital music app can reduce anxiety as well as a standard gas (laughing gas) does in people getting a CT-guided back injection for low back pain.
NîmesAges 18 years+ - NCT06860867Recruiting
Nucleus replacement for single-level discogenic low back pain
This trial tests a new device called PerQdisc for people with chronic low back pain from a single damaged disc in the lower spine. The goal is to see if the device can safely replace the inner gel of the disc without major surgery.
Glendale, ArizonaAges 22–70 - NCT04085406Recruiting
Deep brain stimulation for hard-to-treat low back pain
This trial studies deep brain stimulation (DBS) to reduce severe low back pain that hasn’t improved after many standard treatments and procedures. It may help people whose pain is long-lasting and not fixable with another surgery.
Los Angeles, CaliforniaAges 40–75 - NCT06715969Enrolling by invitation
Comparing two treatments for low back pain
This study compares two different hands-on treatments for low back pain. It may be a good fit if you have ongoing back pain and haven't had recent therapy or medication.
Gaziantep, sehitkamilAges 35–60 - NCT04893954Recruiting
Study of spine changes after weight loss from bariatric surgery
This study looks at how rapid weight loss after bariatric surgery may affect your spine over the following year or more. It may help doctors better predict who gets spine-related problems or improvements after surgery.
ParisAges 18 years+ - NCT06030570Recruiting
Spine rehab program: how well does it work?
This trial tests a spine rehabilitation program that combines different types of care (like physical therapy and counseling) for adults with spine problems that haven't gotten better on their own. It aims to see if this program helps improve function and quality of life.
LeuvenAges 18 years+ - NCT06169488Recruiting
Comparing fusion surgery to rehab for chronic low back pain
This trial compares two approaches for chronic low back pain caused by worn discs: lumbar fusion surgery versus a structured multidisciplinary rehabilitation program. It aims to see which treatment provides better long-term relief and function.
DrammenAges 20–65 - NCT06080464Recruiting
Doctor satisfaction with VERABAND™ for chronic low back pain
This study tests how satisfied doctors are with a wearable device called VERABAND™ that monitors movement in people with chronic low back pain. If your pain limits your ability to move, you may be able to help researchers understand if this device is useful during your regular non-surgical treatment.
La Jolla, CaliforniaAges 18–85 - NCT06013878Recruiting
Testing a tool for caregivers who help with transfers
This study tests a special instrument to measure how caregivers help people with physical disabilities move from one place to another (transfers). It may help improve safety and technique for both caregivers and care recipients.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06009263Recruiting
Exercises for chronic low back pain
This study compares two types of exercises to see which one better strengthens a key lower back muscle. It may help if you have ongoing back pain.
Giza, DokkiAges 25–55 - NCT05880212Recruiting
STOPS low back and leg pain approach for Bangladesh
This trial tests a specific physiotherapy program (“STOPS approach”) for people with long-lasting low back pain or leg pain from the back. It aims to see if the structured treatment, delivered by trained physiotherapists, improves pain and function over about 10 weeks.
Dhaka, UttaraAges 18–65 - NCT05851976RecruitingPhase 4
Duloxetine for short-term non-radiating low back pain
This trial tests duloxetine (a medicine used for certain pain conditions and mood) for easing low back pain that started recently and doesn’t shoot down your leg. It may help reduce pain and improve daily function after an ER visit, but you must meet several safety and medication-use criteria.
The Bronx, New YorkAges 18–64 - NCT05556902Recruiting
Testing how epidural spinal cord stimulation may help chronic pain
This study looks at how a device that sends mild signals to the area around your spinal cord may work for long-lasting (chronic) pain. You may be asked to visit a research lab, have blood taken, and follow the study plan so researchers can understand the treatment’s effects.
Birmingham, AlabamaAges 18–89 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT04730700Recruiting
Radiofrequency treatment test for facet back pain
This study compares a nerve procedure (radiofrequency “neurotomy” using an expandable electrode) to non-procedure medical care for long-lasting low back pain from facet joints. It aims to see whether the procedure helps more safely than conservative treatment.
Kansas City, KansasAges 18 years+ - NCT04381208Recruiting
Using health and movement data to diagnose sacroiliac pain
This study looks at medical records and physical/neurological exam findings to help diagnose sacroiliac joint dysfunction, a common source of chronic low back or buttock pain. It may help your care team better sort out what’s causing your pain and choose the right next steps.
Valencia, ValenciaAges 18 years+ - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99 - NCT07373808Recruiting
Nerve stimulation and exercise for sciatica leg pain
This study tests whether combining a mild electrical stimulation of the sciatic nerve with specific exercises can reduce leg pain from sciatica. It is for people whose nerve-related leg pain has lasted over 6 months and is at least a 3 out of 10 in intensity.
Madrid, MadridAges 18–70 - NCT07377357Recruiting
Electrical stimulation for chronic back-related leg pain
This trial tests if a single session of electrical stimulation to the sciatic nerve can quickly reduce leg pain related to low back problems. It may help if you have had chronic sciatica (leg pain from your back) for more than 6 months and your pain has recently been interfering with daily life.
Madrid, MadridAges 18–70 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for low back pain?
- Yes. Clin2 currently lists 348 recruiting low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.