Clinical trials
Low Back Pain clinical trials
Below are recruiting low back pain clinical trials, each written for real people, not researchers. We’re tracking 345 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
Birmingham, AlabamaAges 18 years+ - NCT07645859Recruiting
High-Intensity vs. Moderate Exercise for Chronic Lower Back Pain
This trial compares two types of exercise programs—one with short, intense bursts of activity and one with steady, moderate activity—to see which works better for people with long-lasting lower back pain that has no clear medical cause. You would participate in supervised exercise sessions over several weeks.
KarachiAges 20–48 - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT07615816Recruiting
Medical massage therapy for active-duty service members with recent lower back pain
This study tests whether massage therapy can help active-duty service members who have had lower back pain for 1–3 months. Researchers want to see if massage reduces pain and improves function.
Joint Base Lewis McChord, WashingtonAges 18–64 - NCT04081896Recruiting
Rehab program for adults with spine pain
This trial studies whether a prescribed physical therapy (rehab) program helps people with spine pain. It may help by improving pain and function when a clinician has already recommended rehabilitation.
San Diego, CaliforniaAges 18–89 - NCT07603609Recruiting
Balance Platform Training for Chronic Low Back Pain
This study tests whether training on a special moving balance platform can help reduce chronic low back pain. You'll practice exercises designed to improve your balance and core stability over several weeks.
AnkaraAges 18–55 - NCT07610044Enrolling by invitation
Pelvic Floor vs. Swiss Ball Exercises for Chronic Low Back Pain
This study tests two exercise approaches—pelvic floor exercises and Swiss ball exercises—to see which better reduces long-term lower back pain in women. Both aim to strengthen core muscles that support your spine.
Lahore, Punjab ProvinceAges 18–35 - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07589790Recruiting
Virtual Reality and Mindfulness for Chronic Low Back Pain
This study tests whether virtual reality combined with mindfulness-based cognitive therapy can help reduce chronic low back pain lasting 3+ months. The trial aims to see if this newer approach eases pain and improves quality of life.
Suzhou, JiangsuAges 20–70 - NCT07588490Recruiting
TENS for sudden severe lower back pain in the emergency room
This trial tests a pain-relief device called TENS (a small machine that sends mild electrical pulses through your skin) for people with sudden, severe lower back pain in the emergency department. Researchers want to see if TENS can help reduce your pain quickly without extra medications.
BrusselsAges 18 years+ - NCT06715761Recruiting
Myofascial release for chronic low back pain in CrossFit athletes
This trial tests if a hands-on or tool-assisted muscle release technique can reduce long-term low back pain and improve posture in people who do CrossFit. If you have had low back pain for at least 12 weeks and do CrossFit regularly, this study may help you find relief.
Goiânia, GoiásAges 18–59 - NCT07579182RecruitingPhase 1
How Exercise and Hormones Affect Pain in Women
This study looks at how exercise affects pain and hormone levels in women. Researchers will ask you about your activity level, do some physical tests, and measure how your body responds to exercise over several visits.
Houston, TexasAges 18–60 - NCT07579039Recruiting
Stretching and tape for pregnancy back pain
This study tests whether combining stretching exercises with special therapeutic tape can safely reduce lower back pain during pregnancy. If it works, it could offer pregnant women a non-medication option to feel better.
Rahim Yar Khan, Punjab ProvinceAges 18–35 - NCT07578181Enrolling by invitation
Aromatherapy Massage for Chronic Lower Back Pain
This study tests whether massage combined with essential oils (lavender, orange, and almond oil) can help reduce chronic lower back pain that has lasted at least 6 months. Researchers want to see if aromatherapy massage is a safe and helpful treatment option.
Kırşehir, MerkezAges 18–65 - NCT07576101Recruiting
Blood Flow Restriction Training for Lower Back Pain
This study tests whether a special exercise technique that carefully reduces blood flow to your legs while exercising can help reduce chronic lower back pain. The goal is to see if this method combined with training can strengthen your muscles and relieve pain more effectively.
IslamabadAges 18–45 - NCT07576244Recruiting
Core exercises and massage therapy for postpartum back pain
This study tests whether core-strengthening exercises combined with a hands-on massage technique called myofascial induction therapy can help reduce back pain after vaginal delivery. It may help you recover faster and manage pain without medication.
Sialkot, Punjab ProvinceAges 20–45 - NCT07559890Recruiting
Nerve ablation for low back pain with Modic changes
This study tests a procedure that uses heat to stop a nerve in the lower back from sending pain signals. It may help people with long-term central low back pain who have not gotten better with other treatments and have Modic changes on MRI.
PragueAges 18 years+ - NCT07567300Recruiting
Understanding Pain Patterns in Migraine and Neck or Back Pain
This study explores how migraine headaches, neck pain, and lower back pain may share similar pain mechanisms in the body. Researchers will ask you questions to understand your pain patterns and help identify connections between these conditions.
Gaziantep, MerkezAges 18–65 - NCT07555496Recruiting
Back Pain Treatment After Spine Surgery: Injection vs. Needling
This study compares two ways to treat long-lasting back pain in people who have had spine surgery: injections into the back muscles versus dry needling (inserting thin needles into tight muscles). Both are combined with physical therapy to see which helps reduce pain better.
St-MaloAges 18 years+ - NCT07555795Recruiting
Game-Based Wearable Sensors to Help Core Muscles and Back Pain
This study tests a wearable belt with sensors and haptic feedback (gentle vibrations) combined with interactive gaming to help strengthen your core muscles and reduce lower back pain. The goal is to make exercise more engaging and effective for chronic back pain.
LondonAges 18 years+ - NCT07543835Recruiting
Yoga and Yoga Nidra for Chronic Low Back Pain
This study compares two types of yoga practices—traditional yoga and a deep relaxation technique called Yoga Nidra—to see which works best for chronic low back pain. You'll attend sessions over several weeks and track how your pain changes.
Orlando, FloridaAges 18–65 - NCT07551323Recruiting
Myofascial Release vs. Pilates for Chronic Low Back Pain
This study compares two hands-on treatment approaches—myofascial release (deep tissue massage) and Pilates exercises—to see which works better for chronic low back pain that isn't caused by nerve damage. If you have persistent lower-back pain, this trial might help you find relief through one of these therapies.
Istanbul, IstanbulAges 18–45
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Common questions
- Are there clinical trials for low back pain?
- Yes. Clin2 currently lists 345 recruiting low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.