Clinical trials
Lower Back Pain clinical trials
Below are recruiting lower back pain clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07166952Recruiting
Nerve Stimulation for Chronic Sacroiliac Joint Pain
This study tests whether the SPRINT system, a device that uses mild electrical pulses to block pain signals from the sacroiliac joint, can help people with chronic pain in that area. It aims to see if this treatment works well for those who have not improved with other therapies.
Charleston, South CarolinaAges 18 years+ - NCT06938568Recruiting
Personalized back training for low back pain
This study tests a personalized back exercise program for people with long-lasting low back pain that limits their daily activities. The goal is to see if it helps improve physical function and reduce pain.
Lucerne, Canton of LucerneAges 18–65 - NCT07137715Recruiting
Wellness and recovery for veterans with chronic back or neck pain
This study tests a psychological program to help veterans manage chronic back or neck pain. It aims to improve your wellbeing and daily function through counseling or coaching sessions.
Aurora, ColoradoAges 18 years+ - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT07122453RecruitingPhase 1
Study of CNTX-3001 for severe chronic low back pain
This trial tests a medicine called CNTX-3001, given as a spinal injection, for people with long-term, severe low back pain that hasn't improved with other treatments.
Napa, CaliforniaAges 18–75 - NCT07112404Recruiting
Dry Needling for Low Back Pain Study
This study tests a type of dry needling (inserting thin needles into muscles) to see if it helps people with and without chronic low back pain. You may join if you have no recent low back pain or if you have had low back pain for at least 3 months, as long as you have not had major back surgery or certain treatments.
Galveston, TexasAges 18–65 - NCT07011537Enrolling by invitation
Digital health program and TENS for chronic low back pain
This trial tests a digital health program combined with a TENS device (a small device that sends gentle electrical pulses to help with pain) for people with ongoing low back pain. It compares this approach to standard care, and you would be randomly assigned to one of the two groups.
Eden Prairie, MinnesotaAges 18 years+ - NCT06963658Recruiting
Isometric Exercise and Pain Sensitivity in Chronic Low Back Pain
This study tests whether a simple, still (isometric) exercise can reduce how sensitive you are to pain. It is for adults with long-term low back pain who can safely do physical therapy exercises.
Bisha, 'Asir RegionAges 18 years+ - NCT06921694Recruiting
Exercise program for lower back pain
This trial tests a combined exercise program with stretching, strength, and aerobic exercises to help relieve chronic lower back pain. It looks at whether specific movements can reduce pain and improve daily function.
Nottingham, NottsAges 18–45 - NCT06906211Recruiting
Ultrasound for chronic back pain in veterans
This trial tests if a gentle ultrasound treatment to a specific part of the brain can help veterans with chronic back pain. It aims to see if targeting the insula can reduce pain that spreads to other areas of the body.
Washington D.C., District of ColumbiaAges 21–75 - NCT06894355Recruiting
Hydrotherapy for athletes with long-term back pain
This trial tests whether group hydrotherapy (water-based exercise) can help athletes with long-term low back pain. It may be a good fit if you are an active athlete, have had back pain for at least 3 months, and train frequently.
NetanyaAges 18 years+ - NCT06818175Recruiting
Study of back muscle tissue and treatment for low back pain
This study looks at the tissue in your lower back using ultrasound and physical exams. It tests a treatment to see if it helps people with new or long-term low back pain, and also compares results to people without pain.
Blacksburg, VirginiaAges 18–50 - NCT06825390Recruiting
Ear stimulation and brain imaging for chronic low back pain
This study tests if a non-invasive ear stimulation technique can change brain activity linked to chronic low back pain. You would have a brain scan before and after the treatment to see how your brain responds.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06619418Recruiting
Home Device Using Sound and Body Stimulation for Back Pain
This study is testing a take-home device that uses sound and gentle body stimulation to help with long-term back pain. It is for adults with chronic low back pain who live near the University of Minnesota and are not taking certain sleep or anxiety medications.
Minneapolis, MinnesotaAges 18 years+ - NCT06540456Enrolling by invitation
Capsaicin patch for nerve-related lower back pain
This study tests a medicated patch called Qutenza (capsaicin) to treat chronic lower back pain that involves nerve damage. The patch is placed on the skin to help reduce pain signals.
Summerville, South CarolinaAges 18 years+ - NCT03707288Recruiting
Exercise study for neck and low back pain in medical students
This study looks at neck and low back pain in medical students and asks participants to follow a set exercise plan for a period of time. It may help researchers understand what kind of exercise support could improve symptoms in students.
Kingston, KingstonAges Any age - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT06282770Recruiting
Light therapy belt for lower back pain after spine surgery
This trial tests whether a special light therapy belt can help reduce long-term lower back pain you still have 1 to 5 years after spinal fusion or decompression surgery.
Los Angeles, CaliforniaAges 18–75 - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99 - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT05843890Recruiting
Personalized pain guide for chronic low back pain
This study tests a tailored (personalized) pain guide to help people with long-lasting lower back pain. It may help by teaching strategies to reduce how pain interferes with daily life.
Ann Arbor, MichiganAges 18 years+ - NCT05721027RecruitingPhase 4
Ibuprofen alone or with a steroid for new sciatica pain
This trial compares ibuprofen alone versus ibuprofen plus dexamethasone (a steroid) for short-term relief of acute nerve-related low back pain that shoots into the buttock or leg. It aims to see which approach reduces pain and improves function after an emergency visit.
The Bronx, New YorkAges 18–70 - NCT04982965RecruitingEarly Phase 1
Study brain changes behind cannabis pain relief
This early study looks at how the brain may respond to cannabis to reduce long-lasting lower back pain. You may be asked to follow strict rules about cannabis, opioids, and safety checks (including MRI) to help researchers understand the brain mechanisms.
La Jolla, CaliforniaAges 21–65 - NCT07760103Recruiting
Core exercises for lower back pain in recreational athletes
This trial compares two sets of core-strengthening exercises to see which works better for athletes with recurring lower back pain. It may help you find a routine that reduces pain and lets you keep being active.
IstanbulAges 18–45
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Common questions
- Are there clinical trials for lower back pain?
- Yes. Clin2 currently lists 126 recruiting lower back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.