Clinical trials
Malaria clinical trials
Below are recruiting malaria clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05911828RecruitingPhase 1
Oral malaria pill study in adults without symptoms
This Phase 1 study tests how safe a combination oral medicine (ZY19489 with ferroquine) is in adults who carry malaria in their blood but have no symptoms. It also studies how the body absorbs and processes the medicines.
LambarénéAges 18–55 - NCT06148792RecruitingPhase 3
Testing a new dose of tafenoquine for vivax malaria
This trial tests a revised dose of a medicine called tafenoquine to more effectively cure vivax malaria (a type of malaria that can come back). It is for people with normal G6PD enzyme levels and a current fever from vivax malaria.
ManausAges 18 years+ - NCT06232954Recruiting
Testing a mosquito-repelling device to prevent malaria in kids
This trial is testing a special device that releases a scent to repel mosquitoes, aiming to reduce malaria in young children in Uganda. If you have a child under 5 and are willing to use the device in your home, this study could help protect your child from malaria.
JinjaAges Up to 5 years - NCT06555809Recruiting
Artesunate study for infants with severe malaria
This trial studies how artesunate works in infants under 2 years old being treated for severe malaria. It aims to learn more about the medicine to help improve treatment for babies.
ParisAges 1 minute–1.9 years - NCT06578572RecruitingPhase 3
Seasonal malaria vaccine study for elimination
This trial tests a seasonal vaccination schedule with the R21 malaria vaccine to help eliminate malaria in your community. It may be a good fit if you are looking for a way to protect yourself or your child from malaria during peak transmission seasons.
NanoroAges 5 months–99 years - NCT06666491RecruitingPhase 3
Comparing two malaria treatments for P. vivax in people 2 and older
This study compares two medicines (tafenoquine and primaquine) taken with chloroquine to treat P. vivax malaria. It aims to see which is safer and works better in Indian participants aged 2 to 64.
AhmedabadAges 2–64 - NCT06862453RecruitingPhase 1
Safety of a new malaria vaccine in healthy adults
This study tests a new malaria vaccine in healthy adults. You will receive the vaccine and then be exposed to the malaria parasite in a controlled setting to check if the vaccine protects you.
TübingenAges 18–45 - NCT06967519RecruitingPhase 4
Optimizing malaria and HIV treatment in Africa
This study aims to find the best way to treat or prevent malaria in children with HIV. It may also help children without HIV who live in areas where malaria is common.
KampalaAges 5–17 - NCT07011511RecruitingPhase 1
Testing a new malaria drug in healthy volunteers
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
NottinghamAges 18–60 - NCT07036159RecruitingPhase 2
Malaria vaccine safety study for children ages 5 months to 5 years
This trial tests a new malaria vaccine in healthy children. It aims to see if the vaccine is safe and how well it works in children who have had their regular childhood shots.
KigaliAges 5 months–5 years - NCT01168271Recruiting
Study malaria risk factors in pregnancy and young children
This study looks at why some people get malaria during pregnancy, and how young children’s bodies respond early in life. It may help researchers understand who is more likely to get malaria and why, which could guide future prevention and care.
BamakoAges 1 day–45 years - NCT07468513RecruitingPhase 4
Primaquine for vivax malaria in G6PD-intermediate or deficient adults
This trial tests how well the drug primaquine works for people with vivax malaria who have intermediate or low levels of an enzyme called G6PD. It aims to find safe and effective treatment options for this group.
ManausAges 18 years+ - NCT05478720RecruitingPhase 1/Phase 2
Tested medicine for children with cerebral malaria
This early-stage study tests how a medicine (involving ondansetron and ceftriaxone) works in people with malaria. It especially focuses on children with cerebral malaria to see if it can improve safety and early effectiveness.
BlantyreAges 1 year+ - NCT07559370RecruitingPhase 2
Imatinib Plus Artemether-Lumefantrine for Uncomplicated Malaria
This trial tests whether adding a cancer drug called imatinib to standard malaria treatment works better and is safe. Researchers will enroll adults and children with uncomplicated malaria caused by P. falciparum parasites and monitor them in the hospital for 2–3 days.
KisumuAges 1–55 - NCT04704999RecruitingPhase 4
Testing the right tafenoquine dose for malaria prevention
This study tests the best dose of tafenoquine to treat people with symptoms from a malaria type called P. vivax and to help prevent it from coming back. You may be eligible if you recently had fever and meet specific blood and safety checks, especially G6PD level.
Siem ReapAges 2 years+ - NCT07675785RecruitingPhase 2
Malaria Vaccine Study for Women Who Could Become Pregnant in Mali
This study tests an experimental malaria vaccine called PfSPZ-LARC2. Researchers want to learn if it is safe and effective for women who could become pregnant, especially in Mali where malaria is common. You would receive several doses of the vaccine and be followed for a few months.
BamakoAges 18–38 - NCT07670377RecruitingPhase 1
Drug interaction study of GSK3772701 in healthy adults aged 18-55
This trial tests how a new drug (GSK3772701) interacts with another common drug (midazolam) in healthy volunteers. It aims to see if one affects how the other works in the body and will help determine safe dosing for future studies.
Miami, FloridaAges 18–55 - NCT07708714RecruitingPhase 1/Phase 2
Hydroxyurea study for teens with sickle cell anemia
This study tests how well a higher dose of hydroxyurea works for teenagers with sickle cell anemia living in areas where malaria is common. It looks at safety and how the treatment affects their daily lives.
KampalaAges 11–18 - NCT03937817Recruiting
Donate samples to study globin gene variants
This study collects common body samples to learn how different globin gene variants work and how they relate to health. Your samples may also be used later for new research, including genetic testing.
Bethesda, MarylandAges 18–70 - NCT05285735Recruiting
Safety study for IV artesunate during pregnancy
This study follows people who were pregnant while receiving IV artesunate to better understand the treatment’s safety for both the mother and the baby. It does not test a new treatment—it collects safety information from real-world care.
Piscataway, New JerseyAges 15–100 - NCT05934318Recruiting
Arginine supplements to help prevent pregnancy complications
This study tests whether taking an arginine-based supplement during pregnancy can help lower the risk of bad pregnancy outcomes. You may be eligible if you are pregnant in the early-to-mid period and meet safety and location requirements.
KisumuAges 16–40 - NCT06068530RecruitingPhase 4
Mass malaria vaccine and drug campaign in Bangladesh villages
This trial is testing whether giving a malaria vaccine and a malaria drug together to whole villages in Bangladesh can help stop the spread of malaria and protect the entire community. It is open to nearly everyone living in selected villages, including children and adults.
BāndarbanAges 6 months+ - NCT06468319Recruiting
Pregnancy Registry in Mali
This registry is collecting information about pregnancies in Mali to help improve health for mothers and babies. You can join either as part of a general community survey or as a pregnant woman receiving care at a health center in Kalifabougou.
Kalifabougou, KoulikoroAges 15–49 - NCT06624631RecruitingPhase 4
Malaria treatment study for children with severe anemia
This study tests a malaria treatment called PDMC in children under 10 who are in the hospital with severe anemia or severe malaria. It aims to see if this treatment can help prevent further health problems.
KisumuAges Up to 9 years
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Common questions
- Are there clinical trials for malaria?
- Yes. Clin2 currently lists 55 recruiting malaria studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malaria trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malaria trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.