Clinical trials
Malaria clinical trials
Below are recruiting malaria clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07456969Recruiting
Breath test for malaria diagnosis in Ethiopia
This trial is testing a new, non-invasive way to diagnose malaria by collecting and analyzing your breath. If you have a fever and are at least 12 years old, you may be able to help researchers see if this breath test works well.
Gonder, AmharaAges 12 years+ - NCT05041556Recruiting
Study of RTS,S malaria vaccine evidence in local areas
This study checks how well evidence about the RTS,S/AS01 malaria vaccine helps inform health policy. You may be included if you live in a specific local area and your child is the right age for the vaccine schedule, and you agree to participate.
KintampoAges 6 months–4.9 years - NCT05790889RecruitingPhase 1/Phase 2
Study of an experimental malaria vaccine in babies in Burkina Faso
This Phase 1/2 study tests a new vaccine meant to protect young children against malaria. If you qualify, your baby would get the study vaccine and be followed for about 12 months to check safety and early signs of protection.
Siglé, Boulkiemdé ProvinceAges 5 months–1.4 years - NCT07036159RecruitingPhase 2
Malaria vaccine safety study for children ages 5 months to 5 years
This trial tests a new malaria vaccine in healthy children. It aims to see if the vaccine is safe and how well it works in children who have had their regular childhood shots.
KigaliAges 5 months–5 years - NCT07021430RecruitingEarly Phase 1
Preventing Malaria in Pregnancy with Focal Drug Treatment
This trial tests whether giving a malaria prevention drug (DHA-PQP) to pregnant women in Kasese District can reduce malaria in pregnancy. Pregnant women at Bugoye Health Center who are less than 22 weeks along may join.
KaseseAges Any age - NCT07011511RecruitingPhase 1
Testing a new malaria drug in healthy volunteers
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
NottinghamAges 18–60 - NCT06967519RecruitingPhase 4
Optimizing malaria and HIV treatment in Africa
This study aims to find the best way to treat or prevent malaria in children with HIV. It may also help children without HIV who live in areas where malaria is common.
KampalaAges 5–17 - NCT06862453RecruitingPhase 1
Safety of a new malaria vaccine in healthy adults
This study tests a new malaria vaccine in healthy adults. You will receive the vaccine and then be exposed to the malaria parasite in a controlled setting to check if the vaccine protects you.
TübingenAges 18–45 - NCT06148792RecruitingPhase 3
Testing a new dose of tafenoquine for vivax malaria
This trial tests a revised dose of a medicine called tafenoquine to more effectively cure vivax malaria (a type of malaria that can come back). It is for people with normal G6PD enzyme levels and a current fever from vivax malaria.
ManausAges 18 years+ - NCT05750628RecruitingPhase 2
Testing malaria medicines in uncomplicated falciparum malaria
This trial studies how well and how safely different anti-malaria medicines work for people who have uncomplicated malaria caused by Plasmodium falciparum. You may be eligible if you have a confirmed infection with a certain parasite level and do not have signs of severe disease or major health conditions.
BanforaAges 2–100 - NCT06666491RecruitingPhase 3
Comparing two malaria treatments for P. vivax in people 2 and older
This study compares two medicines (tafenoquine and primaquine) taken with chloroquine to treat P. vivax malaria. It aims to see which is safer and works better in Indian participants aged 2 to 64.
AhmedabadAges 2–64 - NCT06601712RecruitingPhase 4
Post-discharge malaria prevention in young children
This trial tests whether giving malaria prevention medicine after hospital discharge helps prevent another serious malaria episode in young children. If your child was hospitalized for severe anemia or severe malaria, this study may offer additional protection.
AbomeyAges Up to 9 years - NCT05951595RecruitingPhase 3
Testing three malaria medicines together versus two
This study compares a combination of three medicines to treat uncomplicated malaria, to see if it works as well and is as well tolerated as a two-medicine combination. You may join if you have a specific type of malaria infection in a mild form and meet safety requirements.
Ruhuha, Eastern ProvinceAges 6 months+ - NCT05711485Recruiting
Platelet-directed whole blood transfusion for malaria in young children
This study is testing a new way to use whole blood transfusions to treat severe malaria in young children. It might help children with very low platelet counts and low hemoglobin recover better.
Baltimore, MarylandAges 1 month–4.9 years - NCT05478720RecruitingPhase 1/Phase 2
Tested medicine for children with cerebral malaria
This early-stage study tests how a medicine (involving ondansetron and ceftriaxone) works in people with malaria. It especially focuses on children with cerebral malaria to see if it can improve safety and early effectiveness.
BlantyreAges 1 year+ - NCT05285735Recruiting
Safety study for IV artesunate during pregnancy
This study follows people who were pregnant while receiving IV artesunate to better understand the treatment’s safety for both the mother and the baby. It does not test a new treatment—it collects safety information from real-world care.
Piscataway, New JerseyAges 15–100 - NCT07708714RecruitingPhase 1/Phase 2
Hydroxyurea study for teens with sickle cell anemia
This study tests how well a higher dose of hydroxyurea works for teenagers with sickle cell anemia living in areas where malaria is common. It looks at safety and how the treatment affects their daily lives.
KampalaAges 11–18 - NCT07675785RecruitingPhase 2
Malaria Vaccine Study for Women Who Could Become Pregnant in Mali
This study tests an experimental malaria vaccine called PfSPZ-LARC2. Researchers want to learn if it is safe and effective for women who could become pregnant, especially in Mali where malaria is common. You would receive several doses of the vaccine and be followed for a few months.
BamakoAges 18–38 - NCT07646353RecruitingPhase 1
First-in-human safety study of an investigational drug in healthy adults
This study tests a new investigational drug (GSK4425689A) for the first time in humans. It is a healthy volunteer study to check the safety, side effects, and how the drug moves through the body. It may help in the future development of treatments for malaria.
ManchesterAges 18–65 - NCT07520279Enrolling by invitation
Rapid fever test for tropical diseases
This study tests a new rapid diagnostic tool that can quickly identify tropical fever-causing infections like malaria, dengue, Zika, chikungunya, or leptospirosis from a blood sample. The goal is to help doctors diagnose these infections faster so patients can get treatment sooner.
San Diego, CaliforniaAges 14 years+ - NCT07385287RecruitingPhase 2
Malaria vaccine trial for healthy adults in Burkina Faso
This study tests a new malaria vaccine called PfSPZ-LARC2 in healthy adults living in Burkina Faso. If you qualify, the vaccine is given to see if it can protect you from malaria.
OuagadougouAges 18–50 - NCT07358910Recruiting
Tracking infectious diseases in communities
This study looks at how infections spread in villages in Cambodia. If you live in a participating village, you might help us understand and prevent disease outbreaks.
Phnom Penh, Phnom PenhAges 2–75 - NCT07269314Recruiting
Comparing PCR tests to standard methods for infections
This trial uses stored samples to see if a newer test (PCR) is as good as standard tests at detecting three infections: Pneumocystis (a lung infection), malaria, and leishmaniasis. It does not involve new treatments.
Pavia, LombardyAges Any age - NCT07261280Recruiting
Using Biometric ID to improve malaria vaccine completion
This study is testing a new way to use biometric identification (like fingerprints) to help make sure women get all doses of the malaria vaccine. It is for pregnant women or new mothers who plan to stay in the area.
Oti RegionAges 15–49
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Common questions
- Are there clinical trials for malaria?
- Yes. Clin2 currently lists 55 recruiting malaria studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malaria trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malaria trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.