Clinical trials
Male clinical trials
Below are recruiting male clinical trials, each written for real people, not researchers. We’re tracking 233 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05620940RecruitingPhase 1
IV drug safety and absorption study in healthy men
This Phase 1 study tests two experimental medicines given by IV to healthy men. It checks safety and how the body absorbs and processes the drugs (their “pharmacokinetic” profile).
Herston, QueenslandAges 18–55 - NCT06422455Recruiting
Genetic testing for underserved cancer patients
This study offers free genetic testing to cancer patients and their healthcare providers. It aims to help people who may not have easy access to genetic testing understand their cancer risk.
Los Angeles, CaliforniaAges 18 years+ - NCT06419127Enrolling by invitation
Embryo time-lapse imaging with genetic testing in IVF
This trial tests whether using a special time-lapse camera to watch embryos develop, together with genetic testing (PGT), can help choose the healthiest embryos for IVF. It may help improve the chances of a successful pregnancy.
Fort Lauderdale, FloridaAges 18–50 - NCT06391684Recruiting
Brain flexibility in autistic and non-autistic adults
This study looks at how the brain predicts and adapts in autistic and non-autistic people. Participants will have MRI scans and do simple tasks to help researchers understand flexibility in thinking.
GrenobleAges 18–50 - NCT06353906RecruitingPhase 2
Chemo plus immunotherapy for advanced penile cancer
This trial tests a combination of two chemotherapy drugs (carboplatin and paclitaxel) plus the immunotherapy drug pembrolizumab (Keytruda) for penile cancer that has spread to nearby lymph nodes. The goal is to see if this combination can shrink or control the cancer before or after surgery.
LeuvenAges 18 years+ - NCT06352736Recruiting
Study on urinary symptoms in Chinese men over 40
This study looks at how common lower urinary tract symptoms are in Chinese men aged 40 and older. By participating, you can help researchers understand the impact of these symptoms and find better ways to help people like you.
BeijingAges 40 years+ - NCT06318767Recruiting
Foot Blood Flow Measurements to Predict Limb and Heart Events
This study measures how blood flows through your foot using ultrasound to see if it can predict serious problems with your leg or heart in people with severe circulation problems. The goal is to find a simple test that helps doctors decide the best treatment for you.
AmiensAges 18 years+ - NCT06307977Recruiting
Couples counseling to reduce drug use and HIV risk
This study tests a couple-focused counseling approach to help male couples reduce drug use and lower the risk of HIV. You and your partner would join sessions together to talk about safer choices and support each other.
Detroit, MichiganAges 18–55 - NCT06275620Enrolling by invitationPhase 2
Testing a gene therapy for X-linked retinitis pigmentosa in males
This trial tests two doses of a gene therapy (AGTC-501) in males who already had one eye treated with a similar gene therapy for X-linked retinitis pigmentosa caused by RPGR mutations. The goal is to see if the treatment is safe and can help preserve or improve vision.
Jacksonville, FloridaAges 12 years+ - NCT05874375Recruiting
Study for overactive bladder symptoms in men
This trial looks at a treatment for overactive bladder in adult men. If you qualify, you may be asked to follow study instructions and report symptom changes during treatment.
MaastrichtAges 18 years+ - NCT06217874Recruiting
Collecting Samples and Data for Recurrent or Metastatic Breast Cancer
This study collects tissue samples and health information from people with breast cancer that has spread or come back. It aims to help researchers learn more about the disease and may lead to better treatments.
Rochester, MinnesotaAges 18 years+ - NCT04342026Recruiting
Study environment and hormones in undescended testicles
This study looks at whether environmental exposures and hormone disruption are linked to undescended testicles in children. It may help researchers better understand causes and risk factors, which could improve future care for affected families.
MontpellierAges 1 month–18 years - NCT06179212Recruiting
Comparing exercise tests for men and women with heart disease
This study compares two different exercise test methods to see which works better for men and women with heart disease. The goal is to find a test that can help doctors design better exercise programs for you.
Ottawa, OntarioAges 18 years+ - NCT06092034RecruitingPhase 2
Gene therapy for Danon disease in males
This trial tests a gene therapy called RP-A501 for males with Danon disease, a genetic condition that affects the heart. The treatment aims to fix the faulty gene to help improve heart function and slow disease progression.
La Jolla, CaliforniaAges 8 years+ - NCT06045702Recruiting
Study of CFTR gene in epididymal cells from surgery
This study collects a small tissue sample from the epididymis during planned surgery. The sample is used to study how the CFTR gene works, which may help understand fertility problems in men with cystic fibrosis.
BrestAges 18 years+ - NCT05989243Recruiting
Improving prosthetic socket fit for veterans with leg amputations
This trial tests a new way to make prosthetic sockets fit better for veterans with a leg amputation below or above the knee. If you can walk with your prosthesis, even if it's limited to curbs or stairs, you may be able to join.
Aurora, ColoradoAges 18–65 - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT05962398Enrolling by invitation
Follow-up study for men previously treated with CSL222
This study checks long-term safety and outcomes in men with hemophilia B who previously received CSL222. It may help your care team better understand how well the treatment lasts over many years.
Phoenix, ArizonaAges 18 years+ - NCT05903859RecruitingPhase 3
Study to improve fertility in men after spinal cord injury
This phase 3 study tests a treatment to improve reproductive function (fertility-related measures) in men who have had a traumatic spinal cord injury. If you may be eligible, it could help researchers see whether the treatment improves reproductive outcomes for men with spinal cord injury.
Miami, FloridaAges 18 years+ - NCT05833074Enrolling by invitation
Testing HIV risk again each year for male couples
This study looks at whether repeating HIV testing once a year for male couples at higher risk helps results stay on track over time. It includes couples who previously took part in an earlier study and are willing to keep participating.
Ann Arbor, MichiganAges 17–65 - NCT05611307Recruiting
Heart Health in Testicular Cancer Survivors
This study looks at heart health in men who have survived testicular cancer. It compares those who had different treatments (surgery, chemotherapy, or chemotherapy plus a stem cell transplant) to see if there are hidden signs of heart or blood vessel problems.
Indianapolis, IndianaAges 18–99 - NCT05514223Recruiting
Testing sperm samples to understand lifestyle, gut, and sperm quality
This study measures “free radicals” in sperm to see how lifestyle and the microbiota (gut/community of microbes) may relate to sperm health. You may be asked to provide a semen sample as part of standard fertility testing, unless certain health factors apply.
Groningen, Provincie GroningenAges 18–55 - NCT05479474Recruiting
PRP treatment study for men with testicular infertility
This trial studies whether platelet-rich plasma (PRP) can improve fertility in men with a specific cause of infertility called NOA who have not had success with prior procedures. It may help improve the chance of getting usable sperm for conception.
Stanford, CaliforniaAges 18 years+ - NCT05378347Recruiting
Compare two aortic stent graft types for AAA
This study compares two commercially used stent graft devices to treat an enlarged abdominal aorta (AAA). It aims to see which device works better and is safer over follow-up visits.
Loma Linda, CaliforniaAges 20 years+
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Common questions
- Are there clinical trials for male?
- Yes. Clin2 currently lists 233 recruiting male studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a male trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a male trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.