Clinical trials
Malignancy clinical trials
Below are recruiting malignancy clinical trials, each written for real people, not researchers. We’re tracking 1,543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04811703RecruitingPhase 1
Testing aerosol chemotherapy through the belly for advanced ovarian cancer
This Phase 1 study tests a new way to deliver chemotherapy inside the abdomen (belly) using a pressurized aerosol during a procedure, along with standard blood (IV) chemotherapy. It may help people with advanced ovarian cancer whose tumors have not progressed but are not removable with surgery yet.
LilleAges 18–75 - NCT04829136Recruiting
Fiber supplement for blood cancer treatment
This trial tests whether taking a daily fiber supplement can help people undergoing treatment for blood cancers. It aims to improve gut health and possibly reduce treatment side effects.
Seattle, WashingtonAges 18 years+ - NCT04840264RecruitingPhase 2
Chemotherapy for stomach cancer with blocked intestines
This Phase 2 trial tests a chemotherapy combination (docetaxel, oxaliplatin, and 5-FU) in people with stomach or gastroesophageal cancer that has spread to the lining of the abdomen and is causing an inoperable bowel blockage. It aims to shrink or control the blockage and cancer when surgery cannot be done.
Guangzhou, GuangdongAges 18–75 - NCT04771806Recruiting
MRI-guided adaptive radiation for high-grade brain tumors
This study uses repeated MRI scans with a contrast dye to help doctors tailor (adapt) your radiation treatment over time for a high-grade glioma. It may help improve how accurately radiation targets the tumor as it changes.
Houston, TexasAges 18 years+ - NCT04832698Recruiting
Survey of radiology residents after endovascular simulator training
This study is a survey that asks current interventional and diagnostic radiology residents about their experience after training with an endovascular simulator. Your answers may help improve the simulator training program for future residents.
Houston, TexasAges 18 years+ - NCT04797039Recruiting
MRI-guided freezing treatment for localized prostate cancer
This trial studies a treatment where doctors use MRI pictures to guide freezing of a prostate tumor. It may help men with smaller, well-placed prostate cancers who cannot or do not want surgery or radiation right now.
Rochester, MinnesotaAges 30–100 - NCT04796818Recruiting
MRI scan to track response in colorectal liver metastases
This study uses a special MRI scan to see how colorectal cancer in the liver responds to planned chemotherapy before and after surgery. It may help doctors better measure treatment success and plan care.
Houston, TexasAges 18 years+ - NCT04775745RecruitingPhase 1
Oral drug test for relapsed or refractory B-cell blood cancers
This Phase 1 trial studies LP-168 taken by mouth in people whose B-cell cancers have come back or did not respond to treatment. The study aims to find how the drug works, the right dose, and what side effects to expect.
Durham, North CarolinaAges 18 years+ - NCT04830137RecruitingPhase 1
Test drug NX-2127 for hard-to-treat B-cell blood cancers
This Phase 1 trial tests the safety and early effectiveness of NX-2127 in adults with relapsed or refractory B-cell cancers. If you qualify, you may receive a new targeted treatment because your cancer has returned or not responded to prior therapies.
Duarte, CaliforniaAges 18 years+ - NCT04771130RecruitingPhase 1/Phase 2
Study of BGB-11417 for blood cancers
This early-phase study tests BGB-11417 in people with certain bone-marrow (blood) cancers such as AML, MDS, or MDS/MPN. The goal is to find out how the medicine works and whether it can control the cancer.
Duarte, CaliforniaAges 18 years+ - NCT04686682RecruitingPhase 1/Phase 2
Study drug for adults with advanced cancers or AML
This early study (Phase 1/2) tests a new medicine (JAB-8263) in adults with advanced solid tumors or recurrent/refractory AML. It aims to find a safe dose and see whether it can shrink tumors or control the cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT04684368RecruitingPhase 2
New treatment for children and young adults with a brain tumor
This trial tests a new treatment approach for a rare brain tumor called NGGCT. It aims to see if a different way of treating the tumor can be effective and safe for children and young adults.
Birmingham, AlabamaAges 3–29 - NCT04704648Recruiting
Surgery for a one-eye surface tumor in people with HIV
This study looks at whether removing a suspected pre-cancer/cancer growth on the surface of the eye can be done safely in people living with HIV. It is a feasibility (safety and practical) study, helping doctors refine the best surgical approach and follow-up.
KampalaAges 18 years+ - NCT04752137RecruitingPhase 2
ICG dye imaging during surgery to check tumor edges
This trial tests whether a special dye (ICG) seen during your surgery can help doctors better identify the edges of a tumor in bone or soft tissue. It may help ensure as much of the tumor is removed as safely as possible.
Boston, MassachusettsAges 18 years+ - NCT04763109Recruiting
MRI scan with AI to spot early changes in NF1 children
This study uses special MRI scans plus computer (AI) analysis to look for early, possibly cancer-related skin or tissue changes in children with neurofibromatosis type 1 (NF1). If it works, it could help doctors detect concerning changes earlier and plan care sooner.
Los Angeles, CaliforniaAges 5–17 - NCT04764357Recruiting
Scalp cooling to help prevent chemotherapy-related hair loss in kids
This study looks at whether “cold cap” scalp cooling can help prevent or reduce hair loss in children getting chemotherapy. It’s aimed at kids treated with certain chemotherapy medicines and who may be at risk for losing their hair.
Memphis, TennesseeAges 7 years+ - NCT04731610Recruiting
Radiation after thymoma surgery versus watchful waiting
This trial compares two approaches after complete surgical removal of stage IIb or III thymoma: targeted radiation (conformal post-operative radiotherapy) or no further treatment right away (surveillance). It aims to see whether adding radiation lowers the risk of the cancer coming back without causing unacceptable side effects.
CaenAges 18–75 - NCT04749108RecruitingPhase 2/Phase 3
Tailored treatment for locally advanced rectal cancer after FOLFIRINOX
This trial studies a more customized treatment plan for people with locally advanced rectal (bowel) cancer after they receive FOLFIRINOX chemotherapy. It aims to reduce tumor spread risk and improve outcomes by tailoring the next steps based on scan details and your health status.
Marseille, Bouches Du RhôneAges 18 years+ - NCT04715191RecruitingPhase 1
CAR T therapy for GPC3-positive pediatric solid tumors
This Phase 1 study tests a customized immune-cell treatment (CAR T cells) made to recognize GPC3, a marker found on some tumors. It’s designed for children and young people whose solid tumors have not been cured by standard treatment and who can safely receive this therapy.
Houston, TexasAges 1–21 - NCT04645160RecruitingPhase 1/Phase 2
Tivozanib for bile duct and gallbladder cancers after chemotherapy
This Phase 1/2 trial tests tivozanib (a targeted anti-cancer drug) in people with bile duct or gallbladder cancer that cannot be removed by surgery and has already been treated with first-line chemotherapy. The study looks at how well the drug works and how safe it is in this setting.
Bethesda, MarylandAges 18 years+ - NCT04654208Recruiting
Study people who took palbociclib prescriptions
This study uses prescription records to learn about real-world use of palbociclib (a cancer medicine). You may be included if you’re an adult and have filled at least one palbociclib prescription.
SollentunaAges 18 years+ - NCT04634552RecruitingPhase 2
Talquetamab study for relapsed or refractory multiple myeloma
This trial studies talquetamab, a medicine given to treat multiple myeloma that has come back or did not respond to prior treatment. It may help shrink tumors and improve disease control, depending on how your myeloma measures and your health status.
Birmingham, AlabamaAges 18 years+ - NCT04611087Recruiting
Weight-loss program participants: self-monitoring focus group
This trial is looking to learn from people who finished a specific weight-loss program recently and ask them to share their experiences. The goal is to improve how weight-loss support and tracking work for participants.
Houston, TexasAges Any age - NCT04629677Recruiting
Portal vein stent for narrowed portal blood vessels
This trial looks at whether placing a small metal stent in the portal vein and nearby veins can improve problems caused by major narrowing (or clotting) of these vessels in people with gastrointestinal cancers. If you have significant vessel narrowing, the study may offer a targeted way to relieve pressure and symptoms that are not caused by the tumor directly.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for malignancy?
- Yes. Clin2 currently lists 1,543 recruiting malignancy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignancy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignancy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.