Clinical trials
Melanoma (Skin Cancer) clinical trials
Below are recruiting melanoma (skin cancer) clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07410494RecruitingPhase 1/Phase 2
Personalized donor cell therapy for advanced solid tumors
This trial tests a personalized cell therapy (CAR-NK) using donor immune cells that are engineered to find and attack one or two markers on advanced solid tumors. It may be an option for people whose tumors have these specific markers and have exhausted other treatments.
Beijing, Beijing MunicipalityAges 8–85 - NCT07410676RecruitingPhase 1/Phase 2
Donor NK cells with IL-15 and pembrolizumab for advanced solid tumors
This trial tests a new type of cell therapy (natural killer cells) made from a donor, combined with low-dose IL-15 (a protein that helps these cells work) and sometimes with pembrolizumab (Keytruda), for people with advanced solid tumors that have not responded to standard treatments. The goal is to see if this combination can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges Any age - NCT07406087Recruiting
Navigation support for young adults after cancer
This study tests a navigation program to help cancer survivors ages 21-45 get the follow-up care they need. It may be a good fit if you were diagnosed with certain cancers as a teen or young adult.
Pasadena, CaliforniaAges 21–45 - NCT07376707RecruitingPhase 1
Study of TGI-5 alone or with nivolumab for advanced solid tumors
This trial tests a new drug called TGI-5, either by itself or combined with another drug (nivolumab), for people with advanced cancer that hasn't responded to standard treatments. It's looking for patients with certain types of solid tumors, especially colorectal, melanoma, lung, or others that have stopped responding to therapy.
ShanghaiAges 18 years+ - NCT06605443Recruiting
Precision medicine for large/giant congenital nevus and melanoma
This trial uses a precision medicine approach for people with melanoma. It studies how volatile organic compounds (substances your body releases) might help guide treatment for stage II, III, or IV melanoma.
BarcelonaAges 18 years+ - NCT06608420Recruiting
Precision Medicine Study for Melanoma
This study looks at using precision medicine to better understand and treat melanoma. Patients with a confirmed melanoma diagnosis can join, helping doctors learn more about the disease and improve care.
Barcelona, CataloniaAges Any age - NCT06784778Recruiting
Testing a blood test to predict immunotherapy response
This study is testing a new blood test called IOpener®-Melanoma to see if it can predict which patients with advanced melanoma will respond well to immunotherapy. The goal is to better match treatments to people who will benefit most.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07349940Recruiting
Early skin cancer detection via telemedicine in primary care
This study tests if a telemedicine tool can help find skin tumors early. It may be a good fit if you have a suspicious spot and light skin that burns easily.
BrnoAges 50 years+ - NCT07349303RecruitingPhase 2
Pembrolizumab Before Surgery for Stage IIb/c Melanoma
This trial tests whether giving pembrolizumab (Keytruda) before surgery helps people with a certain type of advanced melanoma (stage IIb/c). The goal is to see if this treatment can improve outcomes before the tumor is removed.
GothenburgAges 18 years+ - NCT07347392Enrolling by invitation
Radiation therapy for head and neck skin cancer study
This study looks at the role of radiation therapy in treating non-melanoma skin cancers (like basal cell carcinoma or squamous cell carcinoma) on the head and neck. It may help doctors better understand how well this treatment works and who benefits most.
Aarhus NAges 18 years+ - NCT07341737RecruitingPhase 1/Phase 2
SL-28 for advanced solid tumors that haven’t responded to treatment
This trial tests a new drug, SL-28, for people with advanced solid tumors that haven’t responded to or cannot be treated with standard therapies. It aims to find a safe dose and see if the drug can help shrink or slow the growth of your cancer.
Sydney, New South WalesAges 18 years+ - NCT07327489Recruiting
Live tumor biopsy study to predict immunotherapy response
This trial studies how well immunotherapy might work by analyzing fresh tumor biopsies. It may help predict which treatments are best for your cancer.
Fort Smith, ArkansasAges 18 years+ - NCT07318051Recruiting
Sample collection for cancer research study
This study collects blood and tumor tissue samples from patients with certain untreated cancers to help researchers develop and improve tests. You may be eligible if you have one of the listed cancer types and have not yet started treatment.
Austin, TexasAges 18 years+ - NCT07280715Recruiting
Tracking immunotherapy side effects in real time
This study uses a smartphone app to track side effects from immunotherapy (a type of cancer treatment that helps your immune system fight cancer) in people with melanoma. The goal is to better understand and manage these side effects as they happen.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07266142Recruiting
Skin cancer research biobank study
This study collects data and samples from people with skin cancer and healthy volunteers to help research. It may be a way to contribute to future treatments.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07201376Recruiting
Testing a skin imaging device for non-melanoma skin cancer
This study tests a device that uses a special light to image skin lesions after applying an FDA-approved cream. It aims to see if the device can help doctors see benign skin growths more clearly before they are removed.
Lebanon, New HampshireAges 18 years+ - NCT07144306Recruiting
AI-powered skin cancer detection study
This trial tests an artificial intelligence system designed to spot skin cancer early. You may be able to join if you are an adult with a suspicious skin spot and can give permission to participate.
LondonAges 1.5 years+ - NCT07136181RecruitingPhase 1/Phase 2
Study of NBM-BMX for advanced uveal melanoma that has spread
This trial tests a new oral drug, NBM-BMX, for people with metastatic uveal melanoma (melanoma of the eye that has spread). It aims to see if the drug is safe and effective. You may join if you have already tried some treatments, including tebentafusp if you are HLA-A*02:01 positive.
Scottsdale, ArizonaAges 18 years+ - NCT07138222Recruiting
Immune therapy and fertility in women and men with melanoma
This study looks at how immune checkpoint inhibitors (a type of immunotherapy) affect fertility and hormone health in premenopausal women and men with melanoma. It aims to understand and manage these side effects while you receive treatment.
Sydney, New South WalesAges 18–60 - NCT07072728RecruitingPhase 2
Psilocybin therapy for anxiety in cancer patients
This trial tests whether psilocybin (a psychedelic drug given with talk therapy) can help people with cancer who have adjustment disorder—a condition where a cancer diagnosis causes severe anxiety or stress. It focuses on reducing anxiety and improving emotional well-being.
Abbotsford, VictoriaAges 18–80 - NCT07042243Recruiting
Florida ASCENT cancer study for patients and providers
This study looks at cancer care in Florida. If you have had cancer in the past and are not currently getting active treatment (like chemotherapy or radiation), this study may help researchers understand how to improve care.
Gainesville, FloridaAges 18–100 - NCT06384053Recruiting
Heat plus radiation for skin cancer in older adults
This trial tests whether adding heat therapy (hyperthermia) to radiation therapy works well for older adults with larger non-melanoma skin cancers. It may help shrink tumors without needing surgery.
Aarau, Canton of AargauAges 65 years+ - NCT06910657RecruitingPhase 1
IDOV-Immune vaccine for advanced solid tumors
This trial tests an experimental virus-based treatment for people with advanced solid tumors that have stopped responding to standard therapies. The treatment is designed to infect and destroy cancer cells while boosting the immune system.
St Louis, MissouriAges 18 years+ - NCT06753136Recruiting
Electrochemotherapy for internal organ tumors
This trial tests a treatment called electrochemotherapy for tumors in internal organs (like the liver or pancreas) when standard treatments are no longer possible. It uses a drug called bleomycin plus electric pulses to target cancer cells.
PadovaAges 18–99
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Common questions
- Are there clinical trials for melanoma (skin cancer)?
- Yes. Clin2 currently lists 153 recruiting melanoma (skin cancer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a melanoma (skin cancer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a melanoma (skin cancer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.