Clinical trials
Metabolic Disease clinical trials
Below are recruiting metabolic disease clinical trials, each written for real people, not researchers. We’re tracking 347 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06953830Enrolling by invitation
Measuring spleen stiffness in veterans with fatty liver disease
This study tests a new way to measure spleen stiffness in veterans with metabolic-dysfunction fatty liver disease. It may help doctors better understand and monitor this condition without invasive procedures.
Columbia, South CarolinaAges 18 years+ - NCT06994871Enrolling by invitation
Exercise and liver fat in fatty liver disease
This study tests if different types of exercise can reduce fat in the liver for people with metabolic fatty liver disease. It might help if you are looking for a non-drug way to improve your liver health.
Nanjing, JiangsuAges 18–45 - NCT06506513Recruiting
Can exercise help fatty liver disease?
This study tests whether a program of physical activity can reduce fat in the muscles and liver of people with MASLD, a type of fatty liver disease linked to metabolism. It looks at how exercise might help improve liver health.
BrusselsAges 18–70 - NCT07456332Enrolling by invitation
Digital lifestyle program for weight loss with HIV and fatty liver
This trial tests a digital lifestyle program (diet and activity coaching) to help people with HIV and fatty liver disease lose weight. It aims to see if the program can reduce body fat in the liver and improve overall health.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT06939569Recruiting
Studying fatty liver disease in people with inflammatory bowel disease
This study looks at how common non-alcoholic fatty liver disease is in people with inflammatory bowel disease (Crohn's or colitis). Researchers want to learn more about the link between the two conditions.
ShanghaiAges 18 years+ - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT06952348Recruiting
Stair climbing vs brisk walking for blood pressure
This study tests whether climbing stairs regularly can lower blood pressure better than brisk walking. It is for people who have high blood pressure, are overweight, and are not very active right now.
StockholmAges 35 years+ - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT06357728Recruiting
Tracking blood sugar during pregnancy
This study uses a continuous glucose monitor to track blood sugar levels during pregnancy in women of Chinese or Indian ethnicity. It aims to better understand glucose patterns in pregnancy.
Singapore, SingaporeAges 21–45 - NCT05236374Recruiting
Daily beef in a heart-healthy diet to study zinc cells
This study tests whether eating daily beef as part of a heart-healthy diet changes how your body’s cells handle zinc, a mineral important for many functions. It’s designed for older adults and includes strict diet and medication rules to keep results accurate.
Davis, CaliforniaAges 55–70 - NCT00628199Enrolling by invitation
Skin sample study to create future cell therapies
This study collects skin cells from people with certain long-term conditions (or specific genetic disorders). Researchers use the cells to try to build new treatments for human disease and disability in the future.
Stanford, CaliforniaAges 1–75 - NCT07062198RecruitingPhase 3
Metabolic supplement for Alzheimer's disease
This trial tests a special supplement combination designed to support brain energy use in people with Alzheimer's. It aims to see if the supplement can help slow cognitive decline.
AlanyaAges 50 years+ - NCT03794531Recruiting
Study of health, stress, and lifestyle changes in Puerto Rico
This study looks at how people’s health, day-to-day stress, and living conditions in Puerto Rico change over time. You might help researchers understand what trends are happening and what could be improved.
San JuanAges 30–75 - NCT06908473Enrolling by invitationPhase 3
Tongmai Jiangtang capsule for heart risks in metabolic syndrome
This trial tests whether the Tongmai Jiangtang capsule can reduce serious heart and stroke problems in older adults with metabolic syndrome who are also at high risk for heart disease. It focuses on people with a specific traditional Chinese medicine pattern called Qi-deficiency and Blood Stasis.
Guangzhou, GuangdongAges 65 years+ - NCT07390422Recruiting
PulsENDO for diabetes and fatty liver
This trial tests a new endoscopic procedure (pulsENDO) for people with type 2 diabetes and fatty liver disease whose blood sugar remains high despite taking diabetes pills. It aims to see if this treatment can improve blood sugar control and liver health.
ShatinAges 18–70 - NCT07330830Recruiting
Genetics and fatty liver disease in Caribbean and Indian Ocean populations
This study looks at how a specific gene (PNPLA3) might affect non-alcoholic fatty liver disease (MASLD) in people from Guadeloupe, French Guiana, and Réunion Island. It aims to understand genetic differences that could explain why some people get the disease.
CayenneAges 18 years+ - NCT07321925Recruiting
Using sound waves to measure liver fat
This study tests a new method that uses sound waves to measure fat in your liver. It could help doctors check liver health without a biopsy.
Ann Arbor, MichiganAges 18 years+ - NCT06798948RecruitingPhase 2
Can a mix of herbs improve mild fatty liver?
This study is testing if a combination of four herbs (artichoke, milk thistle, turmeric, and licorice root) can help people with non-alcoholic mild to moderate fatty liver disease (also called metabolic-associated fatty liver disease). It's a randomized trial, meaning participants are assigned to either the herbal mix or a comparison group. This may offer a natural option to support liver health.
Hangzhou, Select...Ages 18–65 - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07026370Enrolling by invitation
Chinese Health Study: Long-term health follow-up
This study is following up with people who already took part in a large health survey in China. It looks at how multiple health conditions develop over time and why some people stay healthier than others.
Beijing, Beijing MunicipalityAges 20 years+ - NCT05576038Recruiting
Tryptophan to help celiac symptoms improve
This trial tests whether tryptophan (a natural amino acid) can improve symptoms in people with celiac disease who still have symptoms despite following a gluten-free diet. It may help by supporting an internal body signal pathway researchers believe is impaired in some people with celiac disease.
Hamilton, OntarioAges 18–75 - NCT06939985Recruiting
Heart health and metabolism registry for heart failure
This trial is a registry that will follow people with different types of chronic heart failure to better understand how heart health and metabolism are linked. It may help doctors improve care for future patients.
ShanghaiAges 18 years+ - NCT06756789Recruiting
Comparing standard vs. tailored limb lengths in gastric bypass
This study compares two different ways of measuring the length of the small intestine during a type of weight loss surgery called gastric bypass. If you are eligible, you may help determine which approach leads to better weight loss results.
Coimbatore, Tamil NaduAges 18–65 - NCT04407780Recruiting
Cardio-oncology patient registry
This is a registry (a research database) for people who are being followed in cardio-oncology, which means care for heart problems related to cancer or cancer treatments. It may help doctors better understand these conditions and improve future care.
ParisAges 18 years+
Hear when a new Metabolic Disease trial opens
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Common questions
- Are there clinical trials for metabolic disease?
- Yes. Clin2 currently lists 347 recruiting metabolic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.