Clinical trials
Metabolic Syndrome (MetS) clinical trials
Below are recruiting metabolic syndrome (mets) clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05363059Recruiting
Bariatric surgery compared with standard treatment for metabolic syndrome
This trial compares bariatric (weight-loss) surgery with medical (non-surgery) treatment in people with metabolic syndrome, a cluster of risk factors that can affect heart and blood sugar. It aims to see which approach improves these health risks and overall metabolism.
Chongqing, Chongqing MunicipalityAges 18–65 - NCT06271200Recruiting
Lifestyle change and medication for metabolic syndrome
This trial tests a lifestyle program combined with two medications (semaglutide and dapagliflozin) to help people with metabolic syndrome lose weight and improve their health. It may be an option if you are an adult with a BMI of 27 to 45 and have metabolic syndrome.
Zhunan, Miaoli CountyAges 20–65 - NCT06506630Recruiting
Coenzyme Q10 for metabolic syndrome risk
This trial tests whether taking Coenzyme Q10, a natural supplement, can improve heart health markers in people who have or are at high risk for metabolic syndrome. Metabolic syndrome is a group of conditions like high blood sugar, high blood pressure, and belly fat that raise your risk for heart disease and diabetes.
ShenzhenAges 30–90 - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT07040748Recruiting
Virtual reality training to boost thinking skills
This trial tests if immersive virtual reality exercises can improve thinking and memory in adults with metabolic syndrome. It may help if you have noticed some cognitive changes and want to try a non-drug approach.
TerrassaAges 45–70 - NCT07096102Recruiting
Helping people with metabolic syndrome improve health knowledge
This trial tests a program to help people with metabolic syndrome learn how to find and use health information. The goal is to give you tools to better manage your health.
Beijing, Beijing MunicipalityAges 18–75 - NCT07219602RecruitingPhase 3
Study of obicetrapib and ezetimibe for diabetes and metabolic syndrome
This trial tests a combination medication (obicetrapib plus ezetimibe) taken daily to lower cholesterol and triglycerides in people with type 2 diabetes or metabolic syndrome who are already on standard cholesterol treatment. It may help reduce heart risks.
Sun City West, ArizonaAges 18 years+ - NCT07248371Recruiting
Validating multi-omics for metabolic syndrome diseases
This study is testing a new way to look at health information (multi-omics) to better understand conditions related to metabolic syndrome, like diabetes or heart disease. It may help doctors find more personalized treatments.
TaoyuanAges 20 years+ - NCT07410325Recruiting
Health coach and AI app study for metabolic syndrome
This study tests if a health coach supported by an AI-powered smartphone app can help people improve their metabolic syndrome. It is designed for adults who are willing to use the app and follow a structured lifestyle program.
SingaporeAges 21–65 - NCT07426172Recruiting
Lactate levels and metabolism in active adults
This trial looks at how high lactate levels (a natural chemical in your body) affect the way your body uses fat and sugar. It is for people with metabolic syndrome who are already physically active.
San Javier, MurciaAges 18–65 - NCT07659444Recruiting
Metformin withdrawal study for metabolic syndrome
This study looks at what happens when people with metabolic syndrome temporarily stop taking metformin. It aims to understand how their bodies respond when the medication is paused for 14 days.
Toledo, ToledoAges 18 years+ - NCT07051733Enrolling by invitation
Health literacy program for metabolic syndrome
This study tests a health information literacy program to help people with metabolic syndrome better understand and manage their health. It aims to see if the program improves how they take care of their condition.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06528639Recruiting
Exercise program to reduce heart and metabolic risk
This study tests whether a personalized exercise plan guided by a special breathing test can help lower your risk for heart disease and related conditions. You may qualify if you are not very active and have early signs of metabolic syndrome like a larger waist, higher blood sugar, or higher blood pressure.
Beijing, Beijing MunicipalityAges 30–65 - NCT07269847Recruiting
Beef-heavy diet study for adults with pre-diabetes
This study tests whether a diet rich in beef can improve metabolic health in adults with pre-diabetes or metabolic syndrome compared to a typical healthy U.S. diet. Eligible participants will follow one of two meal plans for several weeks.
Guelph, Ontario - onAges 18–74 - NCT05935904Recruiting
Tracking how pregnancy changes metabolic risk markers
This study follows pregnant women to see how common metabolic health markers (like blood sugar, cholesterol, blood pressure, and belly size) change during pregnancy. It may help doctors better understand who is at higher risk for complications during pregnancy.
JimmaAges 18–45 - NCT07229521Recruiting
Nattokinase for heart, gut, sleep, and brain health in metabolic syndrome with sleep issues
This study tests whether a supplement called nattokinase can improve heart health, sleep, thinking, and gut bacteria in people with metabolic syndrome and mild-to-moderate sleep apnea. If you have a larger waist, blood pressure or blood sugar issues, or imbalanced cholesterol, and have been diagnosed with mild or moderate sleep apnea, you may be eligible.
TaipeiAges 18 years+ - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT06072963RecruitingPhase 2
Combining insulin and semaglutide for memory in MCI with metabolic syndrome
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Ramat GanAges 60–90 - NCT06527768Recruiting
Helping with metabolic syndrome and kidney disease through lifestyle changes
This study tests a program that uses WeChat to help people with metabolic syndrome and chronic kidney disease make healthy lifestyle changes. They want to see if this support can improve health and slow down kidney problems.
Chengdu, SichuanAges 18 years+ - NCT06715735Recruiting
A health coaching program for metabolic syndrome with kidney disease
This trial tests if a personalized health coaching program can help people with metabolic syndrome and chronic kidney disease make lasting lifestyle changes. If you have both conditions and are not yet on dialysis, this program may help you manage your health.
Chengdu, SichuanAges 18 years+ - NCT07625332RecruitingPhase 2/Phase 3
Galantamine for Metabolic Syndrome in Spinal Cord Injury
This study tests whether a medication called galantamine can help improve metabolic syndrome (a cluster of health conditions including obesity, high blood sugar, and high cholesterol) in people with chronic spinal cord injury. The goal is to see if this treatment can reduce health risks and improve overall wellness.
West Orange, New JerseyAges 21–75 - NCT05574153Recruiting
Testing heart oxygen reserve in metabolic syndrome and healthy adults
This study measures how much oxygen your heart can use during stress and at rest using an MRI scan. It compares people with metabolic syndrome (a cluster of health risks) to people without those risks, to understand differences in heart function.
Montreal, QuebecAges 18–80 - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65
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Common questions
- Are there clinical trials for metabolic syndrome (mets)?
- Yes. Clin2 currently lists 24 recruiting metabolic syndrome (mets) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic syndrome (mets) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic syndrome (mets) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.