Clinical trials
Metabolic Health clinical trials
Below are recruiting metabolic health clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06535789RecruitingPhase 2/Phase 3
Inhaled insulin vs injections for gestational diabetes
This trial compares an inhaled insulin (Afrezza) to insulin injections for managing blood sugar after meals in women with gestational diabetes. The goal is to see if the inhaled option works as well and is easier to use.
Santa Barbara, CaliforniaAges 18–40 - NCT07646197Recruiting
Peanut Consumption and Fatty Liver Disease in Adults
This study tests whether eating peanuts regularly can help improve fatty liver disease (a condition where fat builds up in the liver). You'll be asked to eat peanuts as part of your diet while researchers track changes in your liver health.
Detroit, MichiganAges 30–70 - NCT05533749Recruiting
E-Health coaching to improve health habits in severe mental illness
This study tests an online (eHealth) program to help people with severe mental illness improve physical health and everyday lifestyle behaviors. If you’re eligible, you’ll be asked to use the internet program and complete questionnaires.
The Hague, South HollandAges 18–65 - NCT05775627Recruiting
Study how sleep affects metabolism in healthy adults
This trial studies how changes in sleep and the body’s daily rhythm may affect metabolism (how your body handles energy and sugar). It is for generally healthy, medication-free young adults who follow a controlled diet and sleep schedule.
Portland, OregonAges 18–40 - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT00109174Recruiting
Brain scan study measuring glutamate and GABA
This study uses MRI to measure certain chemicals in the brain (glutamate and GABA) and see how they are metabolized. You may be able to join if you are healthy, can safely have an MRI, and meet the specific enrollment requirements.
Bethesda, MarylandAges 18–65 - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05748990Recruiting
Brain insulin differences in schizophrenia and thinking
This study tests whether unusual insulin action in the brain is linked to thinking problems and body/metabolic issues in schizophrenia. It may help researchers understand the cause and identify targets for future treatments.
Toronto, OntarioAges 17–45 - NCT06993103RecruitingPhase 4
Pasteurized donor milk for newborns of mothers with diabetes
This trial tests if giving pasteurized donor human milk to newborns of mothers with diabetes can help their health. It compares donor milk to regular baby formula as a supplement when extra feeding is needed soon after birth.
Brisbane, QueenslandAges birth–2 days - NCT07295600Recruiting
Fruits and vegetables for blood sugar control in type 2 diabetes
This study tests whether meals made with local fruits and vegetables can help control blood sugar in people with type 2 diabetes. You will eat special test meals and have your blood sugar checked afterward.
WakisoAges 30–60 - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07026370Enrolling by invitation
Chinese Health Study: Long-term health follow-up
This study is following up with people who already took part in a large health survey in China. It looks at how multiple health conditions develop over time and why some people stay healthier than others.
Beijing, Beijing MunicipalityAges 20 years+ - NCT07202247RecruitingPhase 2
Improving heart health in prostate cancer patients on hormone therapy
This study tests whether combining a time-restricted eating plan, a heart-healthy diet, and a weight-loss medication (GLP-1 receptor agonist) can help improve heart health and weight in men with prostate cancer who are receiving hormone therapy. It aims to reduce the risk of heart problems caused by hormone treatment.
Duarte, CaliforniaAges 30–79 - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT07199491Enrolling by invitation
Healthy lifestyle program for Hispanics with fatty liver disease
This trial tests a culturally tailored lifestyle program for Hispanic adults with fatty liver disease (MASLD). It aims to help improve liver health through diet and activity changes with support from a family member.
Houston, TexasAges 18 years+ - NCT01803451RecruitingEarly Phase 1
Tested after gastric bypass for low blood sugar
This early study looks at a gut hormone–based treatment (GLP-1) and how it affects blood sugar and digestion after gastric bypass. It may help people who are having repeated low blood sugar episodes after surgery.
San Antonio, TexasAges 18–65 - NCT02648009RecruitingPhase 1
Heart metabolic MRI using a special injected tracer
This Phase 1 study tests whether a specialized heart MRI injection can show how the heart uses energy. It may help researchers better understand heart muscle thickening and related conditions, and identify heart-related changes early.
Toronto, OntarioAges 19–75 - NCT05691036Recruiting
Studying bile acid levels and genes in pregnancy itching
This study looks at bile acid levels and possible genetic changes in people with persistent pregnancy itching. The goal is to better understand the cause of intrahepatic cholestasis of pregnancy and related pregnancy outcomes.
Chandigarh, ChandigarhAges 21–45 - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65 - NCT07122700Recruiting
Better tests for fatty liver disease in people with metabolic issues
This study compares new, non-invasive tests to standard liver biopsy for diagnosing fatty liver disease in people with type 2 diabetes or other signs of metabolic syndrome. It aims to see if these simpler tests can replace biopsies.
Miami, FloridaAges 18–75 - NCT06689800Recruiting
Family communication tool for kids getting transplant or cell therapy
This study looks at a family communication tool for children and teens getting stem cell transplants or cellular therapy. It helps families talk about treatment together.
St Louis, MissouriAges 8 years+ - NCT06315725Recruiting
Artificial sweeteners and blood sugar in type 1 diabetes
This study tests whether artificial sweeteners affect blood sugar levels in people with type 1 diabetes. If you use an insulin pump and have well-controlled diabetes, you may be able to join.
Montreal, QuebecAges 18–45 - NCT07212868RecruitingPhase 1
How glucagon affects blood sugar after weight loss surgery
This study looks at how the hormone glucagon affects blood sugar in people who have had gastric bypass or sleeve gastrectomy surgery more than a year ago, compared to people who have not had any gastrointestinal surgery. It aims to understand glucose metabolism better and may help improve care for people after bariatric surgery.
San Antonio, TexasAges 18–65
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Common questions
- Are there clinical trials for metabolic health?
- Yes. Clin2 currently lists 152 recruiting metabolic health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.