Clinical trials
Metabolic Health clinical trials
Below are recruiting metabolic health clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05216042Recruiting
Study of genetics and heart/metabolic health in adults
This study looks at how genetic markers (DNA) relate to heart health and “metabolic” health (how your body manages sugar and fat). You may be asked to provide genetic samples and follow study health checks and protocols to help researchers understand who is at higher risk.
Birmingham, AlabamaAges 18 years+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+ - NCT07646197Recruiting
Peanut Consumption and Fatty Liver Disease in Adults
This study tests whether eating peanuts regularly can help improve fatty liver disease (a condition where fat builds up in the liver). You'll be asked to eat peanuts as part of your diet while researchers track changes in your liver health.
Detroit, MichiganAges 30–70 - NCT06535789RecruitingPhase 2/Phase 3
Inhaled insulin vs injections for gestational diabetes
This trial compares an inhaled insulin (Afrezza) to insulin injections for managing blood sugar after meals in women with gestational diabetes. The goal is to see if the inhaled option works as well and is easier to use.
Santa Barbara, CaliforniaAges 18–40 - NCT06866119Recruiting
Estrogen and heart health in women with early menopause
This study looks at how estrogen therapy affects heart health in women with primary ovarian insufficiency (early menopause). Participants will take a standard estrogen patch and progesterone pill, and researchers will monitor their heart function over time.
Boston, MassachusettsAges 30–40 - NCT05600946Recruiting
Study of body differences in creatine transporter deficiency
This study looks at physical and body features in people with creatine transporter deficiency caused by a specific gene change (SLC6A8). It may help doctors better understand the condition and how it shows up, which can improve future care.
Bethesda, MarylandAges 2–40 - NCT07808619Recruiting
AI health data study for adults
This study is collecting health data to train an AI system that may help predict or improve health outcomes. By joining, you help develop technology that could benefit patients in the future.
Boulder, ColoradoAges 18 years+ - NCT05775627Recruiting
Study how sleep affects metabolism in healthy adults
This trial studies how changes in sleep and the body’s daily rhythm may affect metabolism (how your body handles energy and sugar). It is for generally healthy, medication-free young adults who follow a controlled diet and sleep schedule.
Portland, OregonAges 18–40 - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT00109174Recruiting
Brain chemical scan for healthy participants
This study uses a special MRI scan to measure natural brain chemicals. It helps researchers understand how the brain works in healthy people, which may inform future treatments.
Bethesda, MarylandAges 18–65 - NCT04708431Recruiting
Study of health and wellbeing in people with androgen insensitivity
This study looks at the long-term health and wellbeing of people with androgen insensitivity, a genetic condition that affects how the body responds to androgens (male-type hormones). It may help your care team understand what to watch for over time and improve future guidance for patients and families.
Bethesda, MarylandAges 8–99 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07026370Enrolling by invitation
Chinese Health Study: Long-term health follow-up
This study is following up with people who already took part in a large health survey in China. It looks at how multiple health conditions develop over time and why some people stay healthier than others.
Beijing, Beijing MunicipalityAges 20 years+ - NCT06993103RecruitingPhase 4
Pasteurized donor milk for newborns of mothers with diabetes
This trial tests if giving pasteurized donor human milk to newborns of mothers with diabetes can help their health. It compares donor milk to regular baby formula as a supplement when extra feeding is needed soon after birth.
Brisbane, QueenslandAges birth–2 days - NCT07202247RecruitingPhase 2
Improving heart health in prostate cancer patients on hormone therapy
This study tests whether combining a time-restricted eating plan, a heart-healthy diet, and a weight-loss medication (GLP-1 receptor agonist) can help improve heart health and weight in men with prostate cancer who are receiving hormone therapy. It aims to reduce the risk of heart problems caused by hormone treatment.
Duarte, CaliforniaAges 30–79 - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT07710274Recruiting
Personalized Program for Insulin Resistance in Metabolic Syndrome
This pilot study tests a personalized program called PRISM to help improve how your body responds to insulin. If you have metabolic syndrome (a cluster of conditions like large waist size, high blood pressure, or high blood sugar) and insulin resistance, the study will use a continuous glucose monitor, smart ring, and food logging app to give you tailored feedback.
SingaporeAges 21–70 - NCT07199491Enrolling by invitation
Healthy lifestyle program for Hispanics with fatty liver disease
This trial tests a culturally tailored lifestyle program for Hispanic adults with fatty liver disease (MASLD). It aims to help improve liver health through diet and activity changes with support from a family member.
Houston, TexasAges 18 years+ - NCT01803451RecruitingEarly Phase 1
Tested after gastric bypass for low blood sugar
This early study looks at a gut hormone–based treatment (GLP-1) and how it affects blood sugar and digestion after gastric bypass. It may help people who are having repeated low blood sugar episodes after surgery.
San Antonio, TexasAges 18–65 - NCT02648009RecruitingPhase 1
Heart metabolic MRI using a special injected tracer
This Phase 1 study tests whether a specialized heart MRI injection can show how the heart uses energy. It may help researchers better understand heart muscle thickening and related conditions, and identify heart-related changes early.
Toronto, OntarioAges 19–75 - NCT07461194Recruiting
Broccoli sprout drink timing for better exercise performance
This study looks at whether taking a drink made from broccoli sprouts at a specific time can improve your endurance performance. If you are a trained cyclist or runner, you might get a boost from this natural supplement.
Stockholm, Stockholm CountyAges 18–50 - NCT02823665RecruitingEarly Phase 1
Compare how bariatric surgery affects blood sugar changes
This early trial studies how blood sugar moves in people after certain weight-loss surgery compared with people without surgery. It may help researchers understand why blood sugar can drop too low and how treatments like atropine affect that process.
San Antonio, TexasAges 18–65 - NCT05691036Recruiting
Studying bile acid levels and genes in pregnancy itching
This study looks at bile acid levels and possible genetic changes in people with persistent pregnancy itching. The goal is to better understand the cause of intrahepatic cholestasis of pregnancy and related pregnancy outcomes.
Chandigarh, ChandigarhAges 21–45
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Common questions
- Are there clinical trials for metabolic health?
- Yes. Clin2 currently lists 154 recruiting metabolic health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.